3-(Pent-1-yn-1-yl)aniline | 923027-31-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(Pent-1-yn-1-yl)aniline
• 英文别名: 3-pent-1-ynylaniline
• CAS: 923027-31-0
• 化学式: C₁₁H₁₃N
• 分子量: 159.23
• InChiKey: HBOJSCDYROPCFA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Rod-shaped plant virus nanoparticles as imaging agent platforms
  申请人：CASE WESTERN RESERVE UNIVERSITY

  公开号：US11020497B2

  公开（公告）日：2021-06-01

  A rod-shaped plant virus having an interior surface and an exterior surface, and at least one imaging agent that is linked to the interior and/or exterior surface is described. The rod-shaped viruses can be combined into larger spherical nanoparticles. A rod-shaped plant virus or spherical nanoparticles including an imaging agent can be used in a method of generating an image of a tissue region of a subject such as a tumor or atherosclerotic tissue by administering the virus particle to the subject and generating an image of the tissue region of the subject to which the virus particle has been distributed.

  本文描述了一种具有内表面和外表面的杆状植物病毒，以及至少一种与内表面和/或外表面相连的成像剂。杆状病毒可组合成较大的球形纳米颗粒。杆状植物病毒或包括成像剂的球形纳米粒子可用于生成受试者组织区域（如肿瘤或动脉粥样硬化组织）图像的方法中，具体方法是将病毒颗粒施用于受试者，并生成受试者组织区域的图像，病毒颗粒已分布到该组织区域。