5-Amino[1,1a(2)-biphenyl]-2-sulfonic acid | 4371-24-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-Amino[1,1a(2)-biphenyl]-2-sulfonic acid
• 英文别名: 4-amino-2-phenylbenzenesulfonic acid
• CAS: 4371-24-8
• 化学式: C₁₂H₁₁NO₃S
• 分子量: 249.29
• InChiKey: PWHFNDCQGCRNCU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  88.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• A process for producing steroid derivatives
  申请人：NIPPON KAYAKU KABUSHIKI KAISHA

  公开号：EP0261656A1

  公开（公告）日：1988-03-30

  A process for producing a steroid compound which is useful as an intermediate for synthesizing plant growth regulators, brassinosteroids, and is represented by the general formula (4): wherein R₁ is in which R₂ is a methyl or ethyl, and * indicates the binding site of R₁ to a steroid nucleus, or general formula (5): where in R₁ is as defined above. According to the process disclosed herein, an intermediate for a brassinolide, epibrassinolide, homobrassinolide or derivatives thereof can be produced highly advantageously in the industries.

  一种类固醇化合物的生产工艺，该化合物可用作合成植物生长调节剂--铜生长激素的中间体，其通式为(4)： 其中 R₁ 是 其中 R₂ 是甲基或乙基，* 表示 R₁ 与类固醇核的结合位点，或 通式 (5)： 其中 R₁ 如上定义。 根据本文所公开的工艺，可以在工业中生产出非常有利的黄铜内酯、表黄铜内酯、同黄铜内酯或其衍生物的中间体。
• Biocompatible polymers, process for their preparation and compositions containing them
  申请人：——

  公开号：US20010021758A1

  公开（公告）日：2001-09-13

  A biocompatible polymer constituted by a sequence of identical or different components of the general formula (I): A a X x Y y , in which A represents a monomer, X represents a carboxyl group fixed on a monomer A, Y represents a sulfate or sulfonate group fixed on a monomer A; a represents the number of monomers A, x represents the substitution rate of the set of monomers A by the groups X, y represents the substitution rate of the set of monomers A by the groups Y. The invention also pertains to the pharmaceutical or diagnostic compositions containing at least one polymer of general formula (I).

  一种生物相容性聚合物，由通式(I)相同或不同的组分序列构成：A a X x Y y 其中，A 代表单体，X 代表固定在单体 A 上的羧基，Y 代表固定在单体 A 上的硫酸基或磺酸基；a 代表单体 A 的数量，x 代表一组单体 A 被基团 X 取代的比率，y 代表一组单体 A 被基团 Y 取代的比率。 本发明还涉及含有至少一种通式 (I) 聚合物的药物或诊断组合物。
• BIOCOMPATIBLE POLYMERS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM
  申请人：Barritault Denis

  公开号：US20090012040A1

  公开（公告）日：2009-01-08

  A process for treating fibroses including administering a therapeutically effective amount of a pharmaceutical composition which includes at least one biocompatible polymer of the following general formula (I): A a X x Y y wherein: A represents a monomer selected from the group consisting of a sugar or —(O—CH 2 —CH 2 —CO)—, X represents a carboxyl group bonded to monomer A and is contained within a group according to the following formula: —R—COO—R′, in which R is a bond or an aliphatic hydrocarbon chain, optionally branched and/or unsaturated, and which can contain one or more aromatic rings except for benzylamine and benzylamine sulfonate, and R′ represents a hydrogen atom or a cation, Y represents a sulfate or sulfonate group bonded to monomer A and is contained within a group according to one of the following formulas: —R—O—SO 3 —R′, —R—N—SO 3 —R′, —R—SO 3 —R′, in which R is a bond or an aliphatic hydrocarbon chain, optionally branched and/or unsaturated, and which can contain one or more aromatic rings except for benzylamine and benzylamine sulfonate, and R′ represents a hydrogen atom or a cation, a represents the number of monomers A such that the mass of the polymers of formula (I) is greater than approximately 5,000 da, x represents a substitution rate of the monomers A by the groups X, which is between approximately 20 and 150%, and y represents a substitution rate of the monomers A by the groups Y, which is between approximately 30 and 150%.
• US4891168A
  申请人：——

  公开号：US4891168A

  公开（公告）日：1990-01-02
• US6689741B2
  申请人：——

  公开号：US6689741B2

  公开（公告）日：2004-02-10