2-Hydroxy-5-[(4-hydroxyphenyl)sulfanyl]benzaldehyde | 540748-59-2

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 2-Hydroxy-5-[(4-hydroxyphenyl)sulfanyl]benzaldehyde
• 英文别名: 2-hydroxy-5-(4-hydroxyphenyl)sulfanylbenzaldehyde
• CAS: 540748-59-2
• 化学式: C₁₃H₁₀O₃S
• 分子量: 246.28
• InChiKey: VTTVMBQAOWSJKS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  82.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] BISPHENOLS IN CANCER THERAPY<br/>[FR] BISPHÉNOLS UTILISÉS DANS LE TRAITEMENT DU CANCER
  申请人：UNIV MANITOBA

  公开号：WO2009072002A2

  公开（公告）日：2009-06-11

  The present invention generally relates to anticancer agents and methods of treating cancer. The anticancer agents described herein comprise a bisphenol core and generally act as topoisomerase II inhibitors, though their anticancer activity may be related to other mechanisms as well. The bisphenols discussed therein may also protect certain cells against detrimental effects of topoisomerase II poisons.