4-(5-amino-1,2,4-oxadiazol-3-yl)pyridine | 162704-85-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 4-(5-amino-1,2,4-oxadiazol-3-yl)pyridine
• 英文别名: 3-pyridin-4-yl-[1,2,4]oxadiazol-5-ylamine；3-(4-Pyridinyl)-1,2,4-oxadiazol-5-amine；3-pyridin-4-yl-1,2,4-oxadiazol-5-amine
• CAS: 162704-85-0
• 化学式: C₇H₆N₄O
• 分子量: 162.151
• InChiKey: XMOHGESNXFJGNF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  77.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Cephem derivatives and antimicrobial agents containing the same
  申请人：KATAYAMA SEIYAKUSYO CO. Ltd.

  公开号：EP0641797A1

  公开（公告）日：1995-03-08

  Herein disclosed are novel cephem compounds represented by the following general formula (I), and antimicrobial agents which contains at least one of such novel cephem compounds as an active ingredient.

  以下是表示为以下一般式（I）的新型头孢菌素化合物，以及至少含有这种新型头孢菌素化合物之一作为活性成分的抗微生物药物。
• Compositions useful as inhibitors of rock and other protein kinases
  申请人：Green Jeremy

  公开号：US20060019956A1

  公开（公告）日：2006-01-26

  The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

  本发明涉及作为蛋白激酶抑制剂有用的化合物。本发明还提供了包含所述化合物的药学上可接受的组合物，并且提供了使用这些组合物治疗各种疾病、状况或障碍的方法。
• COMPOSITIONS USEFUL AS INHIBITORS OF ROCK AND OTHER PROTEIN KINASES
  申请人：VERTEX PHARMACEUTICALS INCORPORATED

  公开号：EP1751133A2

  公开（公告）日：2007-02-14
• US7531556B2
  申请人：——

  公开号：US7531556B2

  公开（公告）日：2009-05-12
• [EN] COMPOSITIONS USEFUL AS INHIBITORS OF ROCK AND OTHER PROTEIN KINASES<br/>[FR] COMPOSITIONS UTILES EN TANT QU'INHIBITEURS DE LA ROCK ET D'AUTRES PROTEINES KINASES
  申请人：VERTEX PHARMA

  公开号：WO2005105780A2

  公开（公告）日：2005-11-10

  The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.