1-(3-Bromophenyl)ethane-1,2-diamine | 69810-97-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(3-Bromophenyl)ethane-1,2-diamine
• CAS: 69810-97-5
• 化学式: C₈H₁₁BrN₂
• 分子量: 215.09
• InChiKey: SWWWAQPDPMNNLH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  52
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-(3-Bromophenyl)ethane-1,2-diamine 、 氢氧化钾 、 菲醌 在 乙醇 作用下， 以 乙醇 为溶剂， 反应 11.0h， 生成 2-(3-bromophenyl)dibenzo[f,h]quinoxaline
  参考文献：
  名称：

  Method of Synthesizing Pyrazine Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device

  摘要：

  提供了一种新颖的方法，可以在不使用卤代吡嗪衍生物的合成途径的情况下合成吡嗪衍生物，该卤代吡嗪衍生物是一种合成中间体，其吡嗪骨架被卤化。此外，提供了一种使用上述合成方法获得的吡嗪衍生物作为EL材料的发光元件、发光装置、电子装置或照明装置，具有高发射效率。在该方法中，合成了一种具有芳基或杂环芳基取代基的2-芳基吡嗪衍生物。

  公开号：

  US20130324729A1

文献信息

• Aryl piperidine amides
  申请人：Huang Q. Charles

  公开号：US20050049239A1

  公开（公告）日：2005-03-03

  The invention provides novel GlyT2 inhibiting compounds useful in modulating, treating, or preventing: anxiolytic disorders; a condition requiring treatment of injured mammalian nerve tissue; a condition amenable to treatment through administration of a neurotrophic factor; a neurological disorder; or obesity; an obesity-related disorder.

  该发明提供了新颖的GlyT2抑制化合物，可用于调节、治疗或预防：焦虑症；需要治疗受伤哺乳动物神经组织的状况；适合通过神经营养因子管理治疗的状况；神经系统紊乱；或肥胖症；与肥胖相关的疾病。
• Aryl Piperidine Amides
  申请人：Huang Q. Charles

  公开号：US20080009521A1

  公开（公告）日：2008-01-10

  The invention provides novel GlyT2 inhibiting compounds useful in modulating, treating, or preventing: anxiolytic disorders; a condition requiring treatment of injured mammalian nerve tissue; a condition amenable to treatment through administration of a neurotrophic factor; a neurological disorder; or obesity; an obesity-related disorder.

  本发明提供了新型GlyT2抑制化合物，可用于调节、治疗或预防：抗焦虑障碍；需要治疗受损哺乳动物神经组织的状况；可通过给予神经营养因子进行治疗的状况；神经系统疾病；或肥胖症；肥胖相关疾病。
• Organic Material, Light-Emitting Element, Light-Emitting Device, Electronic Appliance, and Lighting Device
  申请人：Semiconductor Energy Laboratory Co., Ltd.

  公开号：US20130323869A1

  公开（公告）日：2013-12-05

  A novel organic material with fewer impurities, a light-emitting element including the organic material, and a light-emitting device, an electronic appliance, and a lighting device each of which includes the light-emitting element are provided. The organic material is obtained by coupling an aryl halide and an aryl boronic acid or an aryl boronic acid ester. The aryl boronic acid or the aryl boronic acid ester includes at least one of a first impurity in which a boryl group of the aryl boronic acid or the aryl boronic acid ester is substituted by hydrogen and a second impurity in which a molecular mass of 16 or 17 is added to the molecular mass of the first impurity. The concentration of an impurity other than the first impurity and the second impurity is 1% or lower.

  本发明提供了一种具有更少杂质的新型有机材料、包括该有机材料的发光元素、以及包括该发光元素的发光装置、电子器件和照明装置。该有机材料是通过偶联芳基卤化物和芳基硼酸或芳基硼酸酯获得的。所述芳基硼酸或芳基硼酸酯包括以下至少一种杂质：第一杂质，即芳基硼酸或芳基硼酸酯的硼基团被氢取代；第二杂质，即在第一杂质的分子质量上加上16或17。除第一杂质和第二杂质外，其他杂质的浓度为1％或更低。
• Organic material, light-emitting element, light-emitting device, electronic appliance, and lighting device
  申请人：Semiconductor Energy Laboratory Co., Ltd.

  公开号：US09159934B2

  公开（公告）日：2015-10-13

  A novel organic material with fewer impurities, a light-emitting element including the organic material, and a light-emitting device, an electronic appliance, and a lighting device each of which includes the light-emitting element are provided. The organic material is obtained by coupling an aryl halide and an aryl boronic acid or an aryl boronic acid ester. The aryl boronic acid or the aryl boronic acid ester includes at least one of a first impurity in which a boryl group of the aryl boronic acid or the aryl boronic acid ester is substituted by hydrogen and a second impurity in which a molecular mass of 16 or 17 is added to the molecular mass of the first impurity. The concentration of an impurity other than the first impurity and the second impurity is 1% or lower.

  提供了一种新型有机材料，该材料具有较少的杂质，包括该有机材料的发光元素，以及包括该发光元素的发光装置、电子器件和照明装置。该有机材料是通过偶联芳基卤化物和芳基硼酸或芳基硼酸酯得到的。芳基硼酸或芳基硼酸酯包括第一杂质和第二杂质中的至少一种。第一杂质是指芳基硼酸或芳基硼酸酯的硼基团被氢替代的杂质，第二杂质是指分子量比第一杂质增加16或17的杂质。除第一杂质和第二杂质以外的杂质浓度为1％或更低。
• Method of synthesizing pyrazine derivative, and light-emitting element, light-emitting device, electronic device, and lighting device
  申请人：Semiconductor Energy Laboratory Co., Ltd.

  公开号：US09196844B2

  公开（公告）日：2015-11-24

  A novel method includes a synthetic pathway in which α-diketone and a 1-(haloaryl)ethane-1,2-diamine derivative are cyclized to each other to form a 2-(haloaryl)pyrazine derivative. Further, a 2-arylpyrazine derivative having an aryl group or a heteroaryl group as a substituent is synthesized by coupling the 2-(haloaryl)pyrazine derivative obtained by the above synthetic pathway and an arylboronic acid or a heteroarylboronic acid. The 2-arylpyrazine derivative obtained by the novel method is useful for a light-emitting element, a light-emitting device, an electronic device, or a lighting device with high emission efficiency.

  一种新的方法包括合成途径，其中α-二酮和1-(卤代芳基)乙烷-1,2-二胺衍生物相互环化以形成2-(卤代芳基)吡嗪衍生物。进一步，通过将上述合成途径获得的2-(卤代芳基)吡嗪衍生物与芳基硼酸或杂环芳基硼酸偶联，合成具有芳基基团或杂环基团作为取代基的2-芳基吡嗪衍生物。通过这种新方法获得的2-芳基吡嗪衍生物对于具有高发射效率的发光元件、发光装置、电子装置或照明装置非常有用。