Β-碘化甲基胆碱 | 60154-19-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: Β-碘化甲基胆碱
• 中文别名: β-碘化甲基胆碱；碘甲胆碱
• 英文名称: Methylcholine iodide
• 英文别名: 2-hydroxypropyl(trimethyl)azanium;iodide
• CAS: 60154-19-0；26112-50-5
• 化学式: C6H16INO
• 分子量: 245.1
• InChiKey: FOILINVEQJRMPF-UHFFFAOYSA-M

物化性质

• 熔点：
  160 °C

计算性质

• 辛醇/水分配系数(LogP)：
  -2.92
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N,N-二甲基异丙醇胺 、 碘甲烷 以78%的产率得到
  参考文献：
  名称：

  RAJAGOPAL, SRINIVASAN;DIKSIC, MIRKO, J. LABELL. COMPOUNDS AND RADIOPHARM., 29,(1991) N, C. 231-236

  摘要：

  DOI：

文献信息

• Gypsum board with a fluorine-containing antifungal agent
  申请人：Toreki William

  公开号：US20090104144A1

  公开（公告）日：2009-04-23

  A novel gypsum board having improved antifungal properties is disclosed. The board comprises a gypsum core, front and back paper facings, and a polymeric antifungal agent effective at inhibiting fungal growth. A preferred polymeric antifungal agent is polyDADMAC or polyTMMC. The novel gypsum board further comprises a non-polymeric antifungal agent comprising a fluorine-containing quaternary ammonium compound. Preferred non-polymeric ammonium compounds include Tetra-n-butylammonium fluoride and Tetraethylammonium fluoride. The polymeric antifungal agent can be present in the gypsum core and/or on one or both of the paper facings. The non-polymeric antifungal agent may be encapsulated in a material or ionically associated with the polymeric antifungal agent to allow releases of the non-polymeric antifungal agent over time and/or upon exposure to moisture. Methods for preparing the aforementioned novel gypsum board are also disclosed.

  揭示了一种具有改进抗真菌性能的新型石膏板。该板包括石膏芯、正面和背面纸面以及一种聚合物抗真菌剂，有效地抑制真菌生长。首选的聚合物抗真菌剂是聚DADMAC或聚TMMC。该新型石膏板还包括一种非聚合物抗真菌剂，包括含氟季铵化合物。首选的非聚合物铵化合物包括四正丁基氟化铵和四乙基氟化铵。聚合物抗真菌剂可以存在于石膏芯中和/或在正面和/或背面纸面的一侧或两侧。非聚合物抗真菌剂可以封装在材料中或离子地与聚合物抗真菌剂结合，以允许随时间释放非聚合物抗真菌剂和/或在暴露于湿气时释放。还公开了制备上述新型石膏板的方法。
• 1-Amido-3-(2-hydroxyphenoxy)-2-propanol derivatives and a process for preparing 2-amidomethyl-1,4-benzodioxane derivatives
  申请人：Miki Yasushi

  公开号：US20060019993A1

  公开（公告）日：2006-01-26

  An 1-amido-3-(2-hydroxyphenoxy)-2-propanol derivative represented by the following formula (1), wherein cycle A may have further 1 to 4 substituents, and said substituent means a substituent selected from the group consisting of saturated or unsaturated C1-4 alkyl group, aralkyl group in which alkyl moiety has 1 to 4 carbon atoms, aryl group, halogen atom, halogenated C1-4 alkyl group, C2-5 alkanoyl group, mono or dialkylcarbamoyl group in which alkyl moiety has 1 to 4 carbon atoms, cyano group and nitro group, and the substituents at positions 3 and 6, or at positions 4 and 5 on the cycle A are different each other. Other ring may be fused at positions 3 and 4, or at positions 5 and 6 on the cycle A to form a condensed polycyclic hydrocarbon with the cycle A. R 1 is alkanoyl group or aroyl group, and R 2 is hydrogen atom, alkanoyl group or aroyl group, or R 1 and R 2 may be combined together with the N atom to form a cyclic imido group, which is useful as an intermediate of medicines, etc.

  由以下公式（1）表示的1-酰胺-3-(2-羟基苯氧基)-2-丙醇衍生物，其中环A可能有进一步的1到4个取代基，所述取代基是从饱和或不饱和的C1-4烷基，含有1到4个碳原子的芳基烷基，芳基，卤素原子，卤代C1-4烷基，C2-5烷酰基，单或二烷基氨基基，其中烷基部分含有1到4个碳原子，氰基和硝基中选择的取代基，并且在环A上的位置3和6，或在位置4和5上的取代基彼此不同。其他环可能在环A上的位置3和4，或在位置5和6上与环A融合，形成与环A的紧缩多环碳氢化合物。R1是烷酰基或芳酰基，R2是氢原子，烷酰基或芳酰基，或R1和R2可以与N原子结合在一起形成环亚胺基团，可用作药物等的中间体。
• PROCESS FOR THE PREPARATION OF APIXABAN
  申请人：Optimus Drugs Private Limited

  公开号：US20170313695A1

  公开（公告）日：2017-11-02

  The present invention relates to an improved process for the preparation of Apixaban and its intermediates.

  本发明涉及一种改进的阿匹沙班及其中间体的制备工艺。
• [EN] AN IMPROVED PROCESS FOR THE PREPARATION OF APIXABAN<br/>[FR] PROCÉDÉ AMÉLIORÉ POUR LA PRÉPARATION D'APIXABAN
  申请人：OPTIMUS DRUGS (P) LTD

  公开号：WO2017187245A1

  公开（公告）日：2017-11-02

  The present invention relates to an improved process for the preparation of Apixaban and its intermediates.

  本发明涉及一种改进的用于制备阿匹哌班及其中间体的工艺。
• Process for producing glycidyl ether
  申请人：Furukawa Yoshiro

  公开号：US20060030721A1

  公开（公告）日：2006-02-09

  A process for producing a glycidyl ether and an optically active compound thereof with high yield and an optically high purity comprising reacting an alcohol with epihalohydrin in a base to thereby produce a glycidyl ether, the reaction performed in a two-layer system of a nonaqueous organic solvent and an aqueous solvent.

  一种生产高收率和高光学纯度的环氧丙基醚和其光学活性化合物的方法，包括在碱性条件下将醇与环氧卤代丙烷反应以产生环氧丙基醚，反应在非水有机溶剂和水溶剂的两层体系中进行。

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