(4S)-4-methyl-5-phenylpentan-2-one

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4S)-4-methyl-5-phenylpentan-2-one
• 化学式: C₁₂H₁₆O
• 分子量: 176.25
• InChiKey: CXICCRKAEZRHHD-SNVBAGLBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• BICYCLIC SULFONE COMPOUNDS FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE
  申请人：Merck Sharp & Dohme Corp.

  公开号：US20150126493A1

  公开（公告）日：2015-05-07

  The invention provides bicyclic sulfone compounds, pharmaceutical compositions, methods of inhibiting RORy activity, reducing the amount of iL-17 in a subject, and treating immune disorders and inflammatory disorders using such bicyclic sulfone compounds. Another aspect of the invention provides a method of treating a subject suffering from a medical disorder. The method comprises administering to the subject a therapeutically effective amount of one or more bicyclic sulfone compounds described herein. In certain other embodiments, the disorder is rheumatoid arthritis.

  本发明提供了双环磺酮化合物、制药组合物、抑制RORy活性、减少受试者中IL-17含量以及使用这些双环磺酮化合物治疗免疫障碍和炎症性疾病的方法。本发明的另一方面提供了治疗医学疾病的方法。该方法包括向受试者施用所述的一种或多种双环磺酮化合物的治疗有效量。在某些其他实施例中，该疾病是类风湿性关节炎。
• SILICONE COMPOUNDS
  申请人：The Procter & Gamble Company

  公开号：EP3649183A1

  公开（公告）日：2020-05-13
• PROTECTIVE AGENT FOR FOOD PRODUCTS AND THE LIKE AND FOR CURING AND/OR STORAGE ROOMS OF THE SAME
  申请人：PERPRIN S.R.L.

  公开号：EP3809876A1

  公开（公告）日：2021-04-28
• [EN] SILICONE COMPOUNDS<br/>[FR] COMPOSÉS DE SILICONE
  申请人：PROCTER & GAMBLE

  公开号：WO2019010263A1

  公开（公告）日：2019-01-10

  Silicone compounds, delivery compositions, compositions, packaged products and displays comprising such silicone compounds, and processes for making and using such benefit agent delivery compositions, compositions, packaged products and displays. Such compositions have improved deposition and retention properties that may impart improved benefit characteristics to a composition and/or situs. Such silicone compounds solve the further problem of malodor reduction as, in addition to maldor masking, such compounds block a malodor's access to a sensory cell, yet leave such sensor cell open to other molecules, for example scent molecules. Thus, the malodor control technologies disclosed herein do not unduly interfere with the scent of the perfumed or unperfumed situs that is treated with the malodor control technology.
• [EN] PROTECTIVE AGENT FOR FOOD PRODUCTS AND THE LIKE AND FOR CURING AND/OR STORAGE ROOMS OF THE SAME<br/>[FR] AGENT PROTECTEUR DESTINÉ À DES PRODUITS ALIMENTAIRES ET SIMILAIRES ET DESTINÉ À DES CHAMBRES DE TRAITEMENT ET/OU DE STOCKAGE DE CES DERNIERS
  申请人：PERPRIN S R L

  公开号：WO2019243869A1

  公开（公告）日：2019-12-26

  The present invention relates to a protective agent for food products and the like and for curing and/or storage rooms of the same, which includes at least one substance of the type preferably chosen among carboxylic acids and related derivatives, and normally used as a food additive and/or flavouring and/or excipient, and at least one substance, selected between a diluent and an emulsifying agent, preferably chosen among water, food additives, food flavourings and their combinations.