6-Bromo-11-oxa-14-selena-15,16-diazatetracyclo[8.7.0.02,7.013,17]heptadeca-1(10),2(7),3,5,8,13(17),15-heptaene | 1093743-36-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 萘并吡喃类
• 英文名称: 6-Bromo-11-oxa-14-selena-15,16-diazatetracyclo[8.7.0.02,7.013,17]heptadeca-1(10),2(7),3,5,8,13(17),15-heptaene
• CAS: 1093743-36-2
• 化学式: C₁₃H₇BrN₂OSe
• 分子量: 366.075
• InChiKey: CRDAYFNDQCYGCF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.01
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  35
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  [(7-bromo-2,3-dihydrobenzo[f]chromen-1-ylidene)amino]urea 在 selenium(IV) oxide 作用下， 以 溶剂黄146 为溶剂， 反应 12.0h， 以92%的产率得到6-Bromo-11-oxa-14-selena-15,16-diazatetracyclo[8.7.0.02,7.013,17]heptadeca-1(10),2(7),3,5,8,13(17),15-heptaene
  参考文献：
  名称：

  Synthesis and in vitro anti-bacterial evaluation of tetracyclic-ortho-fused 4H-naphtho[1′,2′–5,6]pyrano[3,4-d](1,2,3)selenadiazole and its derivatives

  摘要：

  Synthesis of new heterocyclic compounds 3a-e containing naphthopyran and selenadiazole as the heterocyclic sub-units in the molecule is achieved using high yielding synthetic protocol. These molecules 3a-e have shown moderate anti-bacterial activity against some gram-positive and grain-negative bacterias. (C) 2008 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2008.01.026

文献信息

• Synthesis and in vitro anti-bacterial evaluation of tetracyclic-ortho-fused 4H-naphtho[1′,2′–5,6]pyrano[3,4-d](1,2,3)selenadiazole and its derivatives
  作者：A.V. Karnik、A.M. Kulkarni、N.J. Malviya、B.R. Mourya、B.L. Jadhav

  DOI：10.1016/j.ejmech.2008.01.026

  日期：2008.11

  Synthesis of new heterocyclic compounds 3a-e containing naphthopyran and selenadiazole as the heterocyclic sub-units in the molecule is achieved using high yielding synthetic protocol. These molecules 3a-e have shown moderate anti-bacterial activity against some gram-positive and grain-negative bacterias. (C) 2008 Elsevier Masson SAS. All rights reserved.