N-[3-(1-pyrrolidinyl)phenyl]-2-furamide | 1003709-08-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[3-(1-pyrrolidinyl)phenyl]-2-furamide
• 英文别名: N-(3-pyrrolidin-1-ylphenyl)furan-2-carboxamide
• CAS: 1003709-08-7
• 化学式: C₁₅H₁₆N₂O₂
• 分子量: 256.3
• InChiKey: XCYGIXDQCHLCCK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  45.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE ( NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS )
  申请人：PHARMACIA & UPJOHN COMPANY

  公开号：EP1311505A2

  公开（公告）日：2003-05-21
• [EN] QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE<br/>[FR] FRACTIONS HETEROARYLE SUBSTITUEES PAR QUINUCLIDINE DESTINEES AU TRAITEMENT DE MALADIES
  申请人：UPJOHN CO

  公开号：WO2002015662A2

  公开（公告）日：2002-02-28

  The invention provides compounds of Formula (I): These compounds may be in the form of pharmaceutical salts or compositions, and racemic mixtures or pure enantiomers thereof. The compounds of Formula (I) are useful in pharmaceuticals in which α7 is known to be involved.
• [EN] QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE<br/>[FR] FRAGMENTS HETEROARYLE A SUBSTITUTION QUINUCLIDINE DESTINES AU TRAITEMENT DE MALADIES
  申请人：UPJOHN CO

  公开号：WO2002016355A2

  公开（公告）日：2002-02-28

  The invention provides compound of Formula (I): These compounds may be in the form of pharmaceutical salts or compositions, and racemic mixtures or pure enantiomers thereof. The compounds of Formula (I) are useful in pharmaceuticals in which α7 is known to be involved.