(NE)-N-[(2,4-dichloro-5-nitrophenyl)methylidene]hydroxylamine | 1141894-65-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (NE)-N-[(2,4-dichloro-5-nitrophenyl)methylidene]hydroxylamine
• CAS: 1141894-65-6
• 化学式: C₇H₄Cl₂N₂O₃
• 分子量: 235.026
• InChiKey: DNRZDIOQVNSQPI-XCVCLJGOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  78.4
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (NE)-N-[(2,4-dichloro-5-nitrophenyl)methylidene]hydroxylamine 在 palladium diacetate 、 三苯基膦 作用下， 以 乙腈 为溶剂， 反应 1.0h， 以92%的产率得到2,4-dichloro-5-nitrobenzonitrile
  参考文献：
  名称：

  Highly efficient Pd-catalyzed synthesis of nitriles from aldoximes

  摘要：

  An expedient method of Pd-catalyzed conversion of aldoxime into nitrile was developed. The reaction was carried out under the influence of Pd(OAc)(2)/PPh3 in refluxing CH3CN to provide good to high yields. The use of Cs2CO3 (0.1-0.5 equiv) was crucial in some cases. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.01.150

文献信息

• [EN] HERBICIDAL COMPOUNDS<br/>[FR] COMPOSÉS HERBICIDES
  申请人：SYNGENTA CROP PROTECTION AG

  公开号：WO2020239607A1

  公开（公告）日：2020-12-03

  Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as a pesticides, especially as herbicides.

  式（I）中取代基如权利要求1所定义，作为杀虫剂特别是除草剂有用的化合物。
• HERBICIDAL COMPOUNDS
  申请人：Syngenta Crop Protection AG

  公开号：EP3976603A1

  公开（公告）日：2022-04-06
• Highly efficient Pd-catalyzed synthesis of nitriles from aldoximes
  作者：Hoo Sook Kim、Sung Hwan Kim、Jae Nyoung Kim

  DOI：10.1016/j.tetlet.2009.01.150

  日期：2009.4

  An expedient method of Pd-catalyzed conversion of aldoxime into nitrile was developed. The reaction was carried out under the influence of Pd(OAc)(2)/PPh3 in refluxing CH3CN to provide good to high yields. The use of Cs2CO3 (0.1-0.5 equiv) was crucial in some cases. (C) 2009 Elsevier Ltd. All rights reserved.