5-amino-2-nitrobenzoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-amino-2-nitrobenzoate
• 化学式: C7H5N2O4-
• 分子量: 181.13
• InChiKey: KZZWQCKYLNIOBT-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  112
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates
  申请人：NITTO BOSEKI CO., LTD.

  公开号：EP0347734A2

  公开（公告）日：1989-12-27

  Novel compounds represented by the following formula: wherein A and B each represents a specific amino acid residue and X represents hydrogen or a specific sub­stituent, are excellent as substrates for determination of enzyme activity such as trypsin, etc. The compounds can be synthesized from novel arginyl-3-tert-alkyloxy­carbonyl-4-nitroanilides.

  下式所代表的新型化合物： 其中 A 和 B 各代表一个特定的氨基酸残基，X 代表氢或一个特定的取代基，是测定胰蛋白酶等酶活性的极佳底物。这些化合物可由新型精氨酰-3-叔烷氧基羰基-4-硝基苯胺合成。
• QUANTITATIVE METHOD AND QUANTITATIVE CHIP FOR OBJECTIVE SUBSTANCE
  申请人：ROHM CO., LTD.

  公开号：EP1635175A1

  公开（公告）日：2006-03-15

  The present invention provides a quantitative measurement method and quantitative measurement chip which can perform quantitative measurement of a target substance in a short period of time. The invention provides a quantitative measurement method in which a three dimensional mesh structure material is formed, and quantitative measurements are taken of the target substance using a structure which contains a reagent that reacts with the target substance in the mesh. This method includes a contacting step in which a test specimen which includes the target substance is brought into contact with the structure; a detecting step which, in a process in which a substance whose quantity will increase or decrease by means of the reaction between the target substance and the reagent, detects the substance whose quantity is increasing or decreasing within the structure at a contact interface between the test specimen and the reagent; and a quantitative measurement step which performs quantitative measurement of the target substance based on the results of the detecting step. The mesh structure will allow at least the target substance to pass therethrough.

  本发明提供了一种可在短时间内对目标物质进行定量测量的定量测量方法和定量测量芯片。本发明提供了一种定量测量方法，在该方法中，形成了一种三维网状结构材料，并使用一种含有试剂的结构对目标物质进行定量测量，该试剂会与网状结构中的目标物质发生反应。该方法包括一个接触步骤，在该步骤中，包含目标物质的测试样本与该结构接触；一个检测步骤，在目标物质与试剂反应导致物质数量增加或减少的过程中，在测试样本与试剂的接触界面检测结构内数量增加或减少的物质；以及一个定量测量步骤，根据检测步骤的结果对目标物质进行定量测量。网状结构至少允许目标物质通过。
• METHOD FOR SELECTIVE, SIMULTANEOUS QUANTIFICATION OF TWO SUBSTANCES IN BIOLOGICAL SAMPLE
  申请人：DENKA SEIKEN Co., Ltd.

  公开号：EP1930443A1

  公开（公告）日：2008-06-11

  This invention provides a method for differentially and simultaneously quantifying two target analytes via a single assay operation with the use of a single type of reagent in each of the two steps, i.e., the first step and the second step. In this method, the reaction product associated with the first target analyte is detected at an early stage of the second step and the reaction product associated with the second target analyte is then detected.

  本发明提供了一种通过单一检测操作同时对两种目标分析物进行差异化定量的方法，在两个步骤（即第一步和第二步）中的每一步都使用单一类型的试剂。在该方法中，在第二步的早期阶段检测与第一目标分析物相关的反应产物，然后检测与第二目标分析物相关的反应产物。
• METHOD AND DEVICE FOR DETECTING ANALYTES IN FLUIDS
  申请人：IDEXX LABORATORIES, INC.

  公开号：EP1082614A1

  公开（公告）日：2001-03-14
• DIAGNOSTIC AND TREATMENT OF A MENTAL DISORDER
  申请人：NOVARTIS FORSCHUNGSSTIFTUNG

  公开号：EP1709201A1

  公开（公告）日：2006-10-11