5-Chloro-4-fluoro-2-hydroxy-3-nitrobenzaldehyde

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-Chloro-4-fluoro-2-hydroxy-3-nitrobenzaldehyde
• 化学式: C7H3ClFNO4
• 分子量: 219.55
• InChiKey: YDOLGRHENAFHOP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  83.1
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• INHIBITORS OF STEAROYL-COA DESATURASE
  申请人：Gillespie Paul

  公开号：US20090149466A1

  公开（公告）日：2009-06-11

  Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity.

  提供以下式(I)化合物： 以及药用可接受的盐，其中取代基如说明书中所披露。这些化合物以及包含它们的药物组合物可用于治疗诸如肥胖等疾病。
• US7652013B2
  申请人：——

  公开号：US7652013B2

  公开（公告）日：2010-01-26
• [EN] INHIBITORS OF STEAROYL-COA DESATURASE<br/>[FR] INHIBITEURS DE LA STÉAROYL-COA DÉSATURASE
  申请人：HOFFMANN LA ROCHE

  公开号：WO2009074487A1

  公开（公告）日：2009-06-18

  Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as obesity.