三亚甲基双(三苯基溴化膦) | 7333-67-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 三亚甲基双(三苯基溴化膦)
• 英文名称: Trimethylenebis(triphenylphosphonium bromide)
• 英文别名: triphenyl(3-triphenylphosphaniumylpropyl)phosphanium;dibromide
• CAS: 7333-67-7
• 化学式: C39H36Br2P2
• 分子量: 726.5
• InChiKey: VHCYVFIHNUYVHU-UHFFFAOYSA-L

物化性质

• 熔点：
  333-335°C

计算性质

• 辛醇/水分配系数(LogP)：
  1.37
• 重原子数：
  43
• 可旋转键数：
  10
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 危险类别码：
  R36/37/38
• 安全说明：
  S26,S36
• 危险性防范说明：
  P261,P264,P271,P280,P302+P352,P304+P340,P305+P351+P338,P312,P362,P403+P233,P501
• 危险性描述：
  H315,H319,H335

文献信息

• Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins
  申请人：Iowa State University Research Foundation, Inc.

  公开号：US20030176740A1

  公开（公告）日：2003-09-18

  The present invention provides a method of preparing a phosphonium salt of the formula [R 1 R 2 R 3 P—CR 4 R 5 R 6 ]X, comprising ball-milling a phosphine of the formula R 1 R 2 R 3 P with a compound of the formula XCR 4 R 5 R 6 ; a method of preparing a phosphorus ylide of the formula R 1 R 2 R 3 P═CR 4 R 5 , comprising ball-milling a phosphonium salt of the formula [R 1 R 2 R 3 P—HCR 4 R 5 ]X in the presence of a base; and a method of preparing an olefin of the formula R 4 R 5 C═CR 7 H or R 4 R 5 C═CR 7 R 8 , comprising ball-milling a phosphorus ylide of the formula R 1 R 2 R 3 P═CR 4 R 5 with a compound of the formula R 7 C(O)H or R 7 C(O)R 8 . The inventive method produces phosphonium salts and phosphorus ylides by mechanical processing solid reagents under solvent-free conditions. The advantages of the present invention over conventional solution methods, include: (1) extremely high selectivity; (2) high yields; (3) low processing temperatures; (4) simple and scalable reactions using commercially available equipment; and (5) the complete elimination of solvents from the reaction.

  本发明提供了制备公式为[R1R2R3P-CR4R5R6]X的膦鎵盐的方法，包括将公式为R1R2R3P的膦与公式为XCR4R5R6的化合物进行球磨；制备公式为R1R2R3P═CR4R5的膦鎵叶立德的方法，包括在碱的存在下球磨公式为[R1R2R3P-HCR4R5]X的膦鎵盐；制备公式为R4R5C═CR7H或R4R5C═CR7R8的烯烃的方法，包括将公式为R1R2R3P═CR4R5的膦鎵叶立德与公式为R7C(O)H或R7C(O)R8的化合物进行球磨。本发明通过在无溶剂条件下机械加工固体试剂来生产膦鎵盐和膦鎵叶立德，相比传统的溶液方法，具有以下优点：（1）极高的选择性；（2）高收率；（3）低加工温度；（4）使用商业设备进行简单且可扩展的反应；（5）完全消除反应中的溶剂。
• PHOTOACTIVABLE NITROGEN BASES
  申请人：Dietliker Kurt

  公开号：US20100105794A1

  公开（公告）日：2010-04-29

  Compounds of the Formula (I), (II) and (III) wherein Ar is for example phenylene, biphenylene or naphthylene, all of which are unsubstituted or substituted by C 1 -C 4 -alkyl, C 2 -C 4 -alkenyl, CN, OR 11 , SR 11 , CH2OR 11 , COOR 12 , CONR 12 R 13 or halogen; R 1 , R 2 , R 7 and R 8 independently of one another other are hydrogen or C 1 -C 6 -alkyl; R 3 and R 5 together and R 4 and R 6 together form a C 2 -C 6 -alkylene bridge which is unsubstituted or substituted by one or more C 1 -C 4 -alkyl; R 11 is hydrogen or C 1 -C 6 -alkyl; R 12 and R 13 independently of one another for example are hydrogen, phenyl, C 1 -C 18 -alkyl, C 1 -C 18 -alkyl which is interrupted by one or more O; n is 1-10; X is O, S or NR 10 ; A and A 1 are suitable linking groups; are suitable as photolatent bases.

  公式(I)、(II)和(III)的化合物，其中Ar可以是苯基、联苯基或萘基，它们都可以是未取代或被C1-C4烷基、C2-C4烯基、CN、OR11、SR11、CH2OR11、COOR12、CONR12R13或卤素取代的；R1、R2、R7和R8独立地是氢或C1-C6烷基；R3和R5在一起，R4和R6在一起形成一个未取代或被一个或多个C1-C4烷基取代的C2-C6烷基桥；R11是氢或C1-C6烷基；R12和R13独立地可以是氢、苯基、C1-C18烷基、被一个或多个O中断的C1-C18烷基；n为1-10；X为O、S或NR10；A和A1是适当的连接基团；它们适用于光致潜基。
• NOVEL 15-MEMBERED CYCLIC AZALIDE, NOVEL 16-MEMBERED CYCLIC DIAZALIDE DERIVATIVE, AND PROCESS FOR PRODUCING THESE
  申请人：Meiji Seika Kaisha, Ltd.

  公开号：EP1479687A1

  公开（公告）日：2004-11-24

  A compound represented by the general formula (I) or a salt thereof which has excellent antibacterial activity (R1 represents hydrogen atom or an alkylcarbonyl group, R2 represents hydrogen atom, oxygen atom, hydroxyl group, or an alkylcarbonyloxy group, for example, when R2 is hydrogen atom, R3 represents group (a) (each of R5 and R6 represents hydrogen atom or an alkyl group), R4 represents hydrogen atom or group (c) (each of R8 and R9 represents hydrogen atom or an alkylcarbonyl group), and Me represents methyl group).

  通式 (I) 所代表的化合物或其盐，具有优异的抗菌活性（R1 代表氢原子或烷基羰基，R2 代表氢原子、氧原子、羟基或烷基羰氧基，例如，当 R2 为氢原子时，R3 代表 (a) 基团（R5 和 R6 各代表氢原子或烷基），R4 代表氢原子或 (c) 基团（R8 和 R9 各代表氢原子或烷基羰基），Me 代表甲基）。
• Photoactivable nitrogen bases
  申请人：BASF SE

  公开号：US10928728B2

  公开（公告）日：2021-02-23

  Compounds of the Formula (I), (II) and (III) wherein Ar is for example phenylene, biphenyleneor naphthylene, all of which are unsubstituted or substituted by C1-C4-alkyl, C2-C4-alkenyl, CN, OR11, SR11, CH 2OR11, COOR12, CONR12R13 or halogen; R1, R2, R7 and R8 independently of one another other are hydrogen or C1-C6-alkyl; R3 and R5 together and R4 and R6 together form a C2-C6-alkylene bridge which is unsubstituted or substituted by one ore more C1-C4-alkyl; R11 is hydrogen or C1-C6-alkyl; R12 and R13 independently of one another for example are hydrogen, phenyl, C1-C18-alkyl, C1-C18-alkyl which is interrupted by one or more O; n is 1-10; X is O, S or NR10; A and A1 are suitable linking groups; are suitable as photolatent bases.

  式(I)、(II)和(III)化合物 其中 Ar 例如为亚苯基、联苯基或萘基，它们均未被 C1-C4-烷基、C2-C4-烯基、CN、OR11、SR11、CH 2OR11、COOR12、CONR12R13 或卤素取代或取代；R1、R2、R7 和 R8 相互独立地为氢或 C1-C6-烷基；R3、R2、R7 和 R8 相互独立地为氢或 C1-C6-烷基；R3 和 R5 以及 R4 和 R6 共同形成 C2-C6- 烷基桥，该桥未被取代或被一个或多个 C1-C4- 烷基取代；R11 为氢或 C1-C6- 烷基；R12 和 R13 相互独立地为氢、苯基、C1-C18-烷基、被一个或多个 O 间断的 C1-C18- 烷基；n 为 1-10；X 为 O、S 或 NR10；A 和 A1 为合适的连接基团；适合用作光惰性碱。
• Novel 15-membered cyclic azalide, novel 16-membered cyclic diazalide derivative, and process for producing these
  申请人：Miura Tomoaki

  公开号：US20050209446A1

  公开（公告）日：2005-09-22

  A compound represented by the general formula (I) or a salt thereof which has excellent antibacterial activity (R 1 represents hydrogen atom or an alkylcarbonyl group, R 2 represents hydrogen atom, oxygen atom, hydroxyl group, or an alkylcarbonyloxy group, for example, when R 2 is hydrogen atom, R 3 represents group (a) (each of R 5 and R 6 represents hydrogen atom or an alkyl group), R 4 represents hydrogen atom or group (c) (each of R 8 and R 9 represents hydrogen atom or an alkylcarbonyl group), and Me represents methyl group).

  通式 (I) 所代表的化合物或其盐具有优异的抗菌活性（R 1 代表氢原子或烷基羰基，R 2 代表氢原子、氧原子、羟基或烷基羰氧基，例如，当 R 2 是氢原子时，R 3 代表基团 (a) （R 5 和 R 6 代表氢原子或烷基），R 4 代表氢原子或 (c) 基团（R 8 和 R 9 代表氢原子或烷基羰基），而 Me 代表甲基）。