ethyl 2-{4-[N-(6-chloro-2-quinazolinyl)-N-methylamino]-phenoxy}propionate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: ethyl 2-{4-[N-(6-chloro-2-quinazolinyl)-N-methylamino]-phenoxy}propionate
• 英文别名: ethyl 2-{4-[N-(6-chloro-2-quinazolinyl)-N-methylamino]phenoxy}propionate；ethyl 2-[4-[(6-chloroquinazolin-2-yl)-methylamino]phenoxy]propanoate
• 化学式: C₂₀H₂₀ClN₃O₃
• 分子量: 385.85
• InChiKey: AQLGMZXCXUODSB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  27
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  64.6
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  对甲氨基酚 以 乙醇 为溶剂， 生成 ethyl 2-{4-[N-(6-chloro-2-quinazolinyl)-N-methylamino]-phenoxy}propionate
  参考文献：
  名称：

  -Methyl as a bioisostere for the oxygen link between the aromatic rings of aryloxyphenoxypropionate herbicides

  摘要：

  The herbicidal activity of a set of (N) under bar,methyl arylaminophenoxypropionate esters 3 has been compared to the analogous aryloxyphenoxypropionates 1. The usefulness of (N) under bar-methyl as a novel bioisostere for ether links is shown by the surprisingly high herbicidal activity of the 6-chloroquinazolin-2-yl- and 7-chloro-1,2,4-benzotriazin-3-yl-N-methylamino-phenoxypropionate esters 3h and 3i. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0960-894x(97)00235-7

文献信息

• Substituted phenylamine- and phenyloxy-quinazolines as herbicides
  申请人：——

  公开号：US04675047A1

  公开（公告）日：1987-06-23

  The invention concerns novel compounds of the formula I ##STR1## The compounds are herbicides and in further embodiments the invention provides: processes for the preparation of compounds of formula I; intermediates useful in the preparation of compounds of formula I; compositions containing as active ingredient compounds of formula I; and processes for severely damaging or killing unwanted plants by applying to the plants or to the growth medium of the plants an effective amount of a compound of formula I.

  这项发明涉及公式I的新化合物。这些化合物是除草剂，在进一步的实施方案中，该发明提供：制备公式I化合物的工艺；在制备公式I化合物中有用的中间体；含有公式I化合物作为活性成分的组合物；以及通过向植物或植物生长介质施加公式I化合物的有效量来严重损害或杀死不受欢迎的植物的工艺。
• Quinazolinyloxy(amino)phenoxyalkane carboxylic acid derivatives, process for their synthesis, herbicidal compositions containing them and their use as herbicides
  申请人：ICI AUSTRALIA LIMITED

  公开号：EP0044163A2

  公开（公告）日：1982-01-20

  The invention concerns novel compounds of the formula I The compounds are herbicides and in further embodiments the invention provides: processes for the preparation of compounds of formula I; intermediates useful in the preparation of compounds of formula I; compositions containing as active ingredient compounds of formula I; and processes for severely damaging or killing unwanted plants by applying to the plants or to the growth medium of the plants an effective amount of a compound of formula I.

  本发明涉及式 I 的新型化合物 这些化合物是除草剂，在进一步的实施方案中，本发明提供了：制备式 I 化合物的工艺；用于制备式 I 化合物的中间体；含有作为活性成分的式 I 化合物的组合物；以及通过向植物或植物的生长介质施用有效量的式 I 化合物来严重破坏或杀死不需要的植物的工艺。
• SERBAN, A.;JENSEN, W. A.
  作者：SERBAN, A.、JENSEN, W. A.

  DOI：——

  日期：——
• US4675047A
  申请人：——

  公开号：US4675047A

  公开（公告）日：1987-06-23