N-(2-butenyl)-N-(3-trifluoromethylphenyl)amine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(2-butenyl)-N-(3-trifluoromethylphenyl)amine
• 英文别名: N-crotyl-m-trifluoromethyl aniline；N-crotyl-3-aminobenzotriflouride；N-crotyl-m-aminobenzotrifluoride；N-[(E)-but-2-enyl]-3-(trifluoromethyl)aniline
• 化学式: C₁₁H₁₂F₃N
• 分子量: 215.218
• InChiKey: BAHGHSLXMNNFTC-NSCUHMNNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N-(2-butenyl)-N-(3-trifluoromethylphenyl)amine 生成 1-[(E)-but-2-enyl]-3-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]thiourea
  参考文献：
  名称：

  WOOLARD, FRANK X.

  摘要：

  DOI：
• 作为产物：
  描述：

  (E)-巴豆氯 、 间氨基三氟甲苯 在 sodium chloride 、 potassium carbonate 作用下， 以 N-甲基乙酰胺 为溶剂， 生成 N-(2-butenyl)-N-(3-trifluoromethylphenyl)amine
  参考文献：
  名称：

  3,4-trans-4-ethyl-1-(substituted phenyl)-3- (substituted phenyl)

  摘要：

  4-乙基-1-(取代苯基)-3-取代苯基)吡咯烷-2-酮的3,4-顺式异构体在与碱反应时，可以有效地转化为其3,4-反式异构体，具有高除草活性，可作为除草组合物的有效成分。此外，由下式所表示的3,4-反式-4-乙基-1-(取代苯基)-3-(取代苯基)吡咯烷-2-酮化合物（式中R.sup.2为异丙基基团，X为取代3位的氟原子、氯原子或溴原子，或取代3位和4位或3位和5位的氟原子）特别作为水稻田除草组合物的除草活性成分具有极其优异的活性。

  公开号：

  US05123954A1

文献信息

• Process for preparation of iminothiazolidines
  申请人：ICI Americas Inc.

  公开号：US04877880A1

  公开（公告）日：1989-10-31

  A process for the preparation of certain iminothiazolidines of the formula ##STR1## in which R is halo, nitro, cyano, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, pentahalomethyl, difluoromethyl, pentafluoroethyl, trifluoromethylthio, difluoromethoxy, trifluoromethoxy, tetrafluoroethoxy, methylsulfonyl, C.sub.1 -C.sub.4 alkyloxyiminomethyl, benzyloxyiminomethyl, 1-(C.sub.1 -C.sub.4)alkyl oxyiminoethyl or 1-benzyloxyiminoethyl; R.sub.1 is hydrogen or halo; R.sub.2 is hydrogen, C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 haloalkyl; and R.sub.3 and R.sub.4 are independently hydrogen, halo, nitro, cyano, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 fluoroalkoxy or C.sub.1 -C.sub.4 alkylthio, by reacting a thiourea with methanesulfonic acid or trifluoromethanesulfonic acid in an aprotic solvent for a period of time and at a temperature sufficient to achieve cyclization of the thiourea to form said iminothiazolidine. The thiourea may be prepared by reaction of an N-3-substituted allyl aniline with an arylisothiocyanate.

  一种制备特定亚硫代咪唑啉的方法，其化学式为##STR1##其中R为卤素、硝基、氰基、C.sub.1 -C.sub.4烷基、C.sub.1 -C.sub.4烷氧基、五卤代甲基、二氟甲基、五氟乙基、三氟甲硫基、二氟甲氧基、三氟甲氧基、四氟乙氧基、甲磺酰基、C.sub.1 -C.sub.4烷氧基亚胺甲基、苄氧基亚胺甲基、1-(C.sub.1 -C.sub.4)烷氧基亚氨基乙基或1-苄氧基亚氨基乙基；R.sub.1为氢或卤素；R.sub.2为氢、C.sub.1 -C.sub.4烷基或C.sub.1 -C.sub.4卤代烷基；R.sub.3和R.sub.4独立地为氢、卤素、硝基、氰基、C.sub.1 -C.sub.4烷基、C.sub.1 -C.sub.4卤代烷基、C.sub.1 -C.sub.4烷氧基、C.sub.1 -C.sub.4氟烷氧基或C.sub.1 -C.sub.4烷硫基。通过在无极性溶剂中，将硫脲与甲烷磺酸或三氟甲磺酸反应一段时间，并在足够温度下使硫脲发生环化反应形成所述亚硫代咪唑啉。硫脲可以通过N-3-取代烯丙基苯胺与芳基异硫氰酸酯反应制备。
• 4-ethyl-3-(substituted
  申请人：Mitsui Toatsu Chemicals Incorporated

  公开号：US05131947A1

  公开（公告）日：1992-07-21

  4-Ethyl-3-(phenyl)-1-(3-trifluoromethylphenyl)-2-pyrrolidinones and corresponding compounds bearing a p-substituent on the 1-position phenyl group and/or a substituent on the 3-position phenyl group exhibit selective herbicidal activities against various weeds which cause problems in rice or upland fields, even at extremely low application rates. They can be prepared by reductive dehalogenation of a corresponding .alpha.-haloethyl substituted pyrrolidinone or reductive cyclization of a corresponding N-2-butenyl-N-(substituted phenyl)-haloacetyl-3-trifluoromethylaniline.

  4-乙基-3-(苯基)-1-(3-三氟甲基苯基)-2-吡咯烷酮及相应化合物，在1-位置苯基团上带有对位取代基和/或在3-位置苯基团上带有取代基，对稻田或旱地上引起问题的各种杂草表现出选择性除草活性，甚至在极低的施用率下也有效。它们可以通过对应的α-卤乙基取代的吡咯烷酮进行还原去卤化或对应的N-2-丁烯基-N-(取代苯基)-卤乙酰基-3-三氟甲基苯胺进行还原环化来制备。
• N,N'-diaryl-N-alkylureas and method of use
  申请人：ICI Americas Inc.

  公开号：US04855478A1

  公开（公告）日：1989-08-08

  An N,N-diaryl-N-alkylurea having the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are the same or different and are selected from the group consisting of hydrogen, halogen, cyano, trifluoromethyl, trifluoromethylthio, trifluoromethyl thionyl, trifluoromethane sulfonyl, sulfonamido, substituted phenoxy and substituted pyridyloxy groups wherein the substituent is any one of halogen, cyano, trifluoromethyl, trifluoromethylthio, trifluoromethyl thionyl, trifluoromethane sulfonyl, sulfonamido; and R.sub.5 is selected from the group consisting of alkyl, alkenyl, haloalkyl, haloalkenyl, hydroxyalkyl, hydroxylalkenyl, acetoxyalkyl, acetoxyalkenyl, mercaptoalkyl, and mercaptoalkenyl, wherein the alkyl or alkenyl group in each alkyl- or alkenyl-containing moiety has from 3 to 6 carbon atoms; X is oxygen or sulfur; and agriculturally acceptable salts thereof. Also disclosed is an herbicidal composition and method of treating weeds.

  一种具有以下式子的N，N-二芳基-N-烷基脲化合物##STR1## 其中R.sub.1，R.sub.2，R.sub.3和R.sub.4相同或不同，选自氢，卤素，氰基，三氟甲基，三氟甲基硫醚，三氟甲基硫酰基，三氟甲烷磺酰基，磺酰胺基，取代苯氧基和取代吡啶氧基，其中取代基是卤素，氰基，三氟甲基，三氟甲基硫醚，三氟甲基硫酰基，三氟甲烷磺酰基，磺酰胺基之一; R.sub.5选自烷基，烯基，卤代烷基，卤代烯基，羟基烷基，羟基烯基，乙酰氧基烷基，乙酰氧基烯基，巯基烷基和巯基烯基，其中每个含有烷基或烯基的基团中的烷基或烯基具有3至6个碳原子; X为氧或硫;以及其农业上可接受的盐。还公开了一种除草剂组合物和处理杂草的方法。
• Substituted 1,3-diphenyl pyrrolidones and their use as herbicides
  申请人：ICI Americas Inc.

  公开号：US04960457A1

  公开（公告）日：1990-10-02

  Substituted 1,3-diphenyl pyrrolidones of the formula ##STR1## in which R.sup.1 and R.sup.3 are halogen, trifluoromethyl, cyano, alkyl or alkoxy, R.sup.2 is H or halogen, and R.sup.4 is alkyl or haloalkyl, are useful as herbicidal agents.

  公式为 ##STR1## 的1,3-二苯基吡咯酮衍生物，其中R.sup.1和R.sup.3是卤素、三氟甲基、氰基、烷基或烷氧基，R.sup.2是氢或卤素，R.sup.4是烷基或卤代烷基，可用作除草剂。
• 3,4-trans-4-ethyl-1-(substituted phenyl)-3-(substituted phenyl)pyrrolidin-2-ones, method for preparing the same, and herbicidal compositions containing the same as herbicidally active ingredients
  申请人：MITSUI TOATSU CHEMICALS, Inc.

  公开号：EP0477626A1

  公开（公告）日：1992-04-01

  A 3,4-cis isomer of 4-ethyl-1-(substituted phenyl)-3-(substituted phenyl)pyrrolidin-2-one, when reacted with a base, can be effectively convered into a 3,4-trans isomer thereof which has a high herbicidal activity useful as an effective ingredient for a herbicidal composition. Furthermore, 3,4-trans-4-ethyl-1-(substituted phenyl)-3-(substituted phenyl)pyrrolidin-2-one compounds represented by the formula (III) (wherein R² is an isopropyl group, and X is a fluorine atom, chlorine atom or bromine atom substituted at the 3-position, or fluorine atoms substituted at the 3- and 4-positions or the 3- and 5-positions) have an extremely excellent activity particularly as a herbicidally active ingredient of the herbicidal composition for rice paddy fields.

  4-乙基-1-(取代苯基)-3-(取代苯基)吡咯烷-2-酮的 3,4-顺式异构体与碱反应后，可有效转化为 3,4-反式异构体，该异构体具有很高的除草活性，可作为除草组合物的有效成分。此外，3,4-反式-4-乙基-1-(取代苯基)-3-(取代苯基)吡咯烷-2-酮化合物由式(III)代表 (其中 R² 是异丙基，X 是在 3 位被取代的氟原子、氯原子或溴原子，或在 3 位和 4 位或 3 位和 5 位被取代的氟原子）。 特别是作为稻田除草组合物的除草活性成分，具有极佳的活性。