isosorbide bis-diphenylphosphinite

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃类
• 英文名称: isosorbide bis-diphenylphosphinite
• 英文别名: [(3S,3aS,6R,6aS)-3-diphenylphosphanyloxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl]oxy-diphenylphosphane
• 化学式: C₃₀H₂₈O₄P₂
• 分子量: 514.497
• InChiKey: BMPMGVAZFSQDQD-GOGZTAQTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  36
• 可旋转键数：
  8
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  36.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  isosorbide bis-diphenylphosphinite 在 sulfur 作用下， 以 苯 为溶剂， 反应 2.0h， 以85%的产率得到
  参考文献：
  名称：

  Phosphorylation of 1,4:3,6-Dianhydro-d-sorbitol

  摘要：

  Regioselective mono- and diphosphorylation of 1,4:3,6-dianhydro-d-sorbitol containing two hydroxyl groups differing in steric availability has been studied. The nature of the amine acting as activator and acceptor of hydrogen chloride have had significant impact on the direction of phosphorylation and the structure of the resulting products.

  DOI：

  10.1134/s107036321905013x
• 作为产物：
  描述：

  二苯基氯化膦 、 异山梨醇 在 三乙胺 作用下， 以 苯 为溶剂， 反应 2.0h， 以85%的产率得到isosorbide bis-diphenylphosphinite
  参考文献：
  名称：

  Phosphorylation of 1,4:3,6-Dianhydro-d-sorbitol

  摘要：

  Regioselective mono- and diphosphorylation of 1,4:3,6-dianhydro-d-sorbitol containing two hydroxyl groups differing in steric availability has been studied. The nature of the amine acting as activator and acceptor of hydrogen chloride have had significant impact on the direction of phosphorylation and the structure of the resulting products.

  DOI：

  10.1134/s107036321905013x

文献信息

• Phosphorylation of 1,4:3,6-Dianhydro-d-sorbitol
  作者：K. L. Anfilov、G. I. Kurochkina、G. S. Bratash、M. K. Grachev

  DOI：10.1134/s107036321905013x

  日期：2019.5

  Regioselective mono- and diphosphorylation of 1,4:3,6-dianhydro-d-sorbitol containing two hydroxyl groups differing in steric availability has been studied. The nature of the amine acting as activator and acceptor of hydrogen chloride have had significant impact on the direction of phosphorylation and the structure of the resulting products.