N,N-dimethylethanolammonium acetate

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-dimethylethanolammonium acetate
• 英文别名: 2-Hydroxyethyl(dimethyl)azanium;acetate
• 化学式: C₂H₄O₂*C₄H₁₁NO
• 分子量: 149.19
• InChiKey: VCCSTJCSIICGSB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.37
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  60.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  N,N-二甲基乙醇胺 、 溶剂黄146 反应 24.75h， 以96%的产率得到N,N-dimethylethanolammonium acetate
  参考文献：
  名称：

  在特定任务的 2-羟乙基离子液体中合成酞菁和金属酞菁的便捷有效方法

  摘要：

  摘要 在任务特定的 2-羟乙基基咪唑鎓和铵离子液体中，取代的邻苯二甲腈在 100 °C 下四聚化，以中等产率得到相应的酞菁。此外，在过渡金属盐的存在下，取代的邻苯二甲腈在离子液体中的反应得到相应的金属酞菁。2-羟乙基铵离子液体比2-羟乙基咪唑鎓和非羟基官能化离子液体产生更好的酞菁收率。不同酞菁的分离和分离采用硅胶柱色谱法完成，产物采用多种光谱技术进行表征。图形概要

  DOI：

  10.1080/00397911.2013.867505
• 作为试剂：
  描述：

  肉桂醛 、 氰乙酸乙酯 在 N,N-dimethylethanolammonium acetate 作用下， 反应 0.08h， 以98%的产率得到(2Z,4E)-2-氰基-5-苯基-戊-2,4-二烯酸乙酯
  参考文献：
  名称：

  Dual functions of N,N-dimethylethanolamnium-based ionic liquids for the Knoevenagel reactions at room temperature

  摘要：

  In this work, the hydrogen bond formation ability of cation and anion of the ILs was determined by using the solvatochromic method and was found to be responsible for their catalytic activity in the Knoevenagel reactions. The enhancement in the hydrogen bond donor ability of the cations and the hydrogen bond acceptor ability of the anions can both lead to the increase in the catalytic activity of the ILs. From the proposed reaction mechanism, it was deduced that the cations of the ILs can form hydrogen bond with aldehyde to activate the C=O bond as electrophile, and the anions of the ILs can promote active methylene compound to produce carboanion as nucleophile, showing dual function activation effect in the catalytic processes. In addition, the optimized N,N-dimethylethanolamnium acetate as dual function activator for the Koevenagel reactions benefits from wide substrates tolerance, ambient reaction temperature, easy work-up procedure, and easy reuse of the IL. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.cattod.2012.06.006

文献信息

• Ionic liquid assisted silver-catalyzed one-pot A3-coupling reactions for the synthesis of propargylamines
  作者：Anlian Zhu、Chunyan Du、Yue Zhang、Lingjun Li

  DOI：10.1016/j.molliq.2019.01.142

  日期：2019.4

  A series of ionic liquids with different cations and anions were synthesized and their performances for the silver catalyzed one-pot A3-coupling reactions were investigated. The selection showed that the combination of AgNO3 and ionic liquid [TMG][TFA] showed highest catalytic activity. This catalytic system was then utilized for the production a series of propargylamines with satisfactory isolated

  合成了一系列具有不同阳离子和阴离子的离子液体，研究了它们在银催化的一锅A 3偶联反应中的性能。选择表明，AgNO 3的组合离子液体[TMG] [TFA]表现出最高的催化活性。然后将该催化体系用于生产具有令人满意的分离产率的一系列炔丙基胺。该反应系统非常简单且易于进行，因为不需要惰性气体或任何其他附加溶剂，碱性添加剂。这也带来了以下后处理程序的便利以及催化系统的回收和再利用。认为离子液体通过与底物或作为助催化剂和配体的催化剂的相互作用而参与了催化过程。
• Biocompatible Ionic Liquid Promote One-Pot Synthesis of 2-Amino-4H-Chromenes Under Ambient Conditions
  作者：Anlian Zhu、Qixing Li、Wanlu Feng、Dongshuang Fan、Lingjun Li

  DOI：10.1007/s10562-020-03332-7

  日期：2021.3

  The synthesis of 2-amino-4H-chromenes through one-pot multicomponent reactions has received great attention due to the high atom efficiency and the broad bioactivities of the products. Here, the catalytic performances of a series of functional ionic liquids towards this type of reaction were investigated and the results showed that the ionic liquid, choline acetate ([Choline][Ac]), could efficiently

  通过一锅多组分反应合成2-氨基-4H-色烯由于其高原子效率和广泛的生物活性而备受关注。在这里，研究了一系列功能性离子液体对此类反应的催化性能，结果表明离子液体醋酸胆碱（[Choline][Ac]）可以在室温下有效地促进该反应，而无需有机溶剂。该反应易于进行，后续处理程序非常简单。通过萃取和洗涤程序即可获得纯品，无需柱分离程序。有趣的是，这个反应系统可以很容易地放大到几克，这表明它在工业应用中的前景。此外，离子液体 [Choline][Ac] 可以很容易地由廉价且具有生物相容性的材料制备，并且可以回收和再利用至少五个循环。在室温下，在乙酸胆碱的催化下，各种醛、丙二腈和活化酚可以转化为相应的 2-氨基-4H-色烯，分离产率从良好到极好。
• Ionothermal Synthesis of Metal Chalcogenides M₂Ag₃Sb₃S₇ (M = Rb, Cs) Displaying Nonlinear Optical Activity in the Infrared Region
  作者：Gang Yang、Long-Hua Li、Chao Wu、Mark G. Humphrey、Chi Zhang

  DOI：10.1021/acs.inorgchem.9b01262

  日期：2019.10.7

  that Rb2Ag3Sb3S7 affords a powder SHG performance of ∼0.5 × AgGaS2 with type-I phase matching, while Cs2Ag3Sb3S7 shows a slightly stronger SHG performance of ∼0.6 × AgGaS2 with type-I phase matching. Both compounds possess broad transparency ranges (∼0.6–20 μm), suggesting their potential as infrared (IR) nonlinear optical (NLO) materials. The laser damage thresholds (LDTs) of both Rb2Ag3Sb3S7 and Cs2Ag3Sb3S7

  通过电热方法合成了两种有趣的非中心对称金属硫属元素化物Rb 2 Ag 3 Sb 3 S 7和Cs 2 Ag 3 Sb 3 S 7。化合物Rb 2 Ag 3 Sb 3 S 7和Cs 2 Ag 3 Sb 3 S 7的晶体具有同构构型，由二维（2D）阴离子网络∞ [Ag 3 Sb 3 S 7 ] 2–组成。，被碱金属M +阳离子分裂。Rb 2 Ag 3 Sb 3 S 7和Cs 2 Ag 3 Sb 3 S 7的带隙分别为2.11和2.02 eV 。次谐波世代（SHG）研究表明，Rb 2 Ag 3 Sb 3 S 7具有约0.5×AgGaS 2的粉末SHG性能，且具有I型相匹配，而Cs 2 Ag 3 Sb 3 S 7的SHG性能稍强0.6×AgGaS 2的性能具有I型相位匹配。两种化合物都具有较宽的透明度范围（约0.6–20μm），表明它们具有作为红外（IR）非线性光学（NLO）材料的潜力。Rb 2 Ag
• Extraction process of sulfur compounds from fuels with protic ionic liquids
  作者：Zhuo Li、Jinggang Xu、Dan Li、Changping Li

  DOI：10.1039/c4ra16186f

  日期：——

  Sulfur compounds in fuels are hazardous to the environment and present a great challenge. In this study, a series of protic ionic liquids (PILs) was designed and their extraction desulfurization capability was evaluated.

  燃料中的硫化合物对环境有害，构成了一项巨大挑战。本研究设计了一系列质子离子液体（PILs），并评估了它们的萃取脱硫能力。
• Cleaner enzymatic production of biodiesel with easy separation procedures triggered by a biocompatible hydrophilic ionic liquid
  作者：Anlian Zhu、Wanlu Feng、Zhiyong Li、Shuang Cheng、Qianhan Chen、Dongshuang Fan、Yuanyang Guo、Lingjun Li、Jianji Wang

  DOI：10.1039/c9gc03796a

  日期：——

  A biocompatible and hydrophilic ionic liquid was found to efficiently promote the enzymatic production of biodiesel with excellent yields from different oil resources.

  一种生物相容性和亲水性离子液体被发现能够有效促进不同油资源的酶促生物柴油生产，产率优异。