dicholinium oxalate

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: dicholinium oxalate
• 英文别名: choline-oxalic acid；2-Hydroxyethyl(trimethyl)azanium;oxalate；2-hydroxyethyl(trimethyl)azanium;oxalate
• 化学式: C₂O₄*2C₅H₁₄NO
• 分子量: 296.364
• InChiKey: MOZDKJDZSVLARA-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -3.83
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  101
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  氯化胆碱 在 sodium hydroxide 作用下， 以 水 为溶剂， 反应 12.0h， 生成 dicholinium oxalate
  参考文献：
  名称：

  Design of environmentally friendly ionic liquid aqueous two-phase systems for the efficient and high activity extraction of proteins

  摘要：

  离子液体(ILs)作为常规挥发性有机溶剂的环保替代品，在工业过程中有着广泛的应用。然而，许多离子液体对生物体具有毒性且难以生物降解。在本工作中，设计和合成了一系列环境友好的胆碱类离子液体。研究发现，这些离子液体与热敏、无毒且可生物降解的聚丙二醇400(PPG400)可以形成水相双离子液体体系(ATPSs)。为了理解这些ATPSs的相形成过程及其在蛋白质提取/分离中的可能应用，在25 °C下测量了这些ATPSs的双结曲线和系线，并系统地研究了离子液体阴离子结构、蛋白质性质以及上相和下相浓度差异对一些典型蛋白质分配行为的影响。结果表明，牛血清白蛋白(BSA)、胰蛋白酶、木瓜蛋白酶和溶菌酶可以有效地富集到ATPSs的离子液体富集相中，在优化条件下单步提取效率可高达86.4-99.9%。此外，使用N-苯甲酰-L-精氨酸乙酯作为底物，测定了水和水合离子液体溶液中天然胰蛋白酶的酶活性，经过13个月的储存后活性增加到约127%。此外，PPG400通过简单加热即可回收并在下一次提取过程中重复使用。这避免了在应用聚乙二醇(PEG)+盐和离子液体+盐ATPSs时产生的高盐水量不可持续的问题。

  DOI：

  10.1039/c2gc35890e

文献信息

• High density phosphate brines and methods for making and using same
  申请人：Clearwater International LLC

  公开号：EP2264119A1

  公开（公告）日：2010-12-22

  New heavy phosphate brines are disclosed, where the water soluble phosphate brines include two or more metal phosphate. Methods for making and using the heavy phosphate brines in drilling, completion, and fracturing operations are also disclosed.

  公开了新型重磷酸盐盐水，其中水溶性磷酸盐盐水包括两种或两种以上的金属磷酸盐。还公开了在钻井、完井和压裂作业中制造和使用重磷酸盐盐水的方法。
• Shale Inhibition additive for oil/gas down hole fluids and methods for making and using same
  申请人：Kippie P. David

  公开号：US20060116296A1

  公开（公告）日：2006-06-01

  An under-balanced drilling fluid additive is disclosed which reduces reactive shale and/or clay swelling during under-balanced drilling operations, where the additive includes an effective amount of a choline salt. A method for under-balanced drilling is also disclosed including the step of circulating a drilling fluid including an effective amount of a choline salt to reduce reactive shale and/or clay swelling during under-balanced drilling operations.
• Corrosion inhibitor systems for low, moderate and high temperature fluids and methods for making and using same
  申请人：Gatlin W. Larry

  公开号：US20060194700A1

  公开（公告）日：2006-08-31

  A corrosion control system is disclosed including an anionic oxygen inhibitor, a cationic acid inhibitor or dispersant, and a noxious species inhibitor or scavenger for use in a fluid in contact with a metallic surface at low temperature, moderate temperature and especially at high temperature. A drilling fluid, a completion fluid, a production fluid and a geothermal fluid including an effective amount of the corrosion control system is also disclosed as well as methods for making and using same.
• Shale inhibition additive for oil/gas down hole fluids and methods for making and using same
  申请人：Kippie P. David

  公开号：US20080039345A1

  公开（公告）日：2008-02-14

  An under-balanced drilling fluid additive is disclosed which reduces reactive shale and/or clay swelling during under-balanced drilling operations, where the additive includes an effective amount of a choline salt. A method for under-balanced drilling is also disclosed including the step of circulating a drilling fluid including an effective amount of a choline salt to reduce reactive shale and/or clay swelling during under-balanced drilling operations.
• HIGH DENSITY PHOSPHATE BRINES AND METHODS FOR MAKING AND USING SAME
  申请人：Falana Olusegun M.

  公开号：US20100305010A1

  公开（公告）日：2010-12-02

  New heavy phosphate brines are disclosed, where the water soluble phosphate brines include two or more metal phosphate. Methods for making and using the heavy phosphate brines in drilling, completion, and fracturing operations are also disclosed.