2,5-dimethylsulphonic acid dihydrate | 273200-04-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,5-dimethylsulphonic acid dihydrate
• 英文别名: 2,5-Me2C6H3SO3H*2H2O；2,5-Dimethylbenzenesulfonic acid hydrate；2,5-dimethylbenzenesulfonic acid;hydrate
• CAS: 273200-04-7
• 化学式: C₈H₁₀O₃S*2H₂O
• 分子量: 222.262
• InChiKey: VXKQOMCABCHKAQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.73
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  63.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,5-dimethylsulphonic acid dihydrate 以 甲醇 为溶剂， 生成 (1-ethyl-3-methylimidazolium) 2,5-dimethylbenzenesulfonate
  参考文献：
  名称：

  Ionic liquids for selective sulfur dioxide absorption

  摘要：

  公开号：

  EP2692413B1

文献信息

• Direct Hydrolysis of Hydrated Organotin Cations:  Synthesis and Structural Characterization of {[<i>n</i>-Bu₂Sn(OH₂)(Phen)(O₃SC₆H₃-2,5-Me₂)]⁺[2,5-Me₂C₆H₃SO₃]^-} (Phen = 1,10-phenanthroline) and {[<i>n</i>-Bu₂Sn(μ-OH)(O₃SC₆H₃-2,5-Me₂)]₂}<i>_n</i>
  作者：Vadapalli Chandrasekhar、Puja Singh、Kandasamy Gopal

  DOI：10.1021/om0701625

  日期：2007.5.1

  5-Me2)]2}n (4). Formation of 4 also occurs in the reaction of 3 with pyridine as well as in a 1:1 reaction of [n-Bu2SnO]n with 2,5-Me2C6H3SO3H·2H2O. The molecular structure of 3 contains a six-coordinate tin with a coordination environment comprising the chelating phenanthroline ligands, two butyl substituents, one water molecule, and one sulfonate ligand. Extensive hydrogen-bonding interactions (O−H- - -O

  [反应Ñ -Bu 2的Sn（OH 2）4 ] 2+ [2,5-ME 2 ç 6 ħ 3 SO 3 - ] 2 }（2）与1,10-菲咯啉，得到[ Ñ -Bu 2 Sn（OH 2）（Phen）（O 3 SC 6 H 3 -2,5-Me 2）] + [2,5-Me 2 C 6 H 3 SO 3 ] - }（3）是通过螯合菲咯啉配体取代两个水分子，而磺酸盐配体取代一个水分子。相反，2经过吡啶处理后发生水解，从而形成[ n -Bu 2 Sn（μ-OH）（O 3 SC 6 H 3 -2,5-Me 2）] 2 } n（4） 。在3与吡啶的反应以及[ n -Bu 2 SnO] n与2,5-Me 2 C 6 H 3的1：1反应中也发生4的形成。SO 3 ·H·2H 2 O的分子结构3包含一个用包含螯合剂菲咯啉配，二丁基的取代基，一个水分子和一种磺酸酯配体的配位环境六配位锡。广泛氢键相互作用（O-H-
• Structural studies of diorganotin(IV) sulfonates: The synthesis of [(n-C4H9)2Sn{OSO2C6H3(CH3)2-2,5}2] and [(n-C4H9)2Sn{OSO2R)2·2(hexamethylphosphoric triamide)] [R=CH3, 4-C6H4CH3, 2,5-C6H3(CH3)2, 2,4,6-C6H2(CH3)3] and crystal structures of [(n-C4H9)2Sn(μ-OH)(OSO2C6H3(CH3)2-2,5)]2 and (n-C4H9)2Sn{OSO2R)2·2(hexamethylphosphoric triamide)] [R=4-C6H4CH3, 2,5-C6H3(CH3)2, 2,4,6-C6H2(CH3)3]
  作者：Ramesh Kapoor、Anand Gupta、Paloth Venugopalan、Ajay Pal Singh Pannu、Maninder Singh Hundal、Pratibha Kapoor

  DOI：10.1016/j.jorganchem.2008.11.031

  日期：2009.3

  [(n-C4H9)2SnOSO2C6H3(CH3)2-2,5}2] (1) and [(n-C4H9)2SnOSO2R)2 · 2HMPA] [R = CH3 (3), 4-C6H4CH3 (4), 2,5-C6H3(CH3)2 (5), 2,4,6-C6H2(CH3)3 (6)] have been carried out to study their structures and to delineate the coordination behavior of the weakly coordinating sulfonate anions. Compound 1 hydrolyzes slowly to [(n-C4H9)2Sn(μ-OH)(OSO2C6H3(CH3)2-2,5)]2 (2) when kept in CH2Cl2 for a few days. The crystal structure shows

  的[（的合成Ñ -C 4 ħ 9）2 Sn的OSO 2 C ^ 6 ħ 3（CH 3）2 - 2，5 } 2（] 1）和[（Ñ -C 4 ħ 9）2 Sn的OSO 2 R）2  ·2HMPA] [R = CH 3（3）， 4 -C 6 H 4 CH 3（4），2，5 -C 6 ħ 3（CH 3）2（5），2，4，6 -C 6 H ^ 2（CH 3）3（6）]已经进行了研究其结构和划定的协调行为弱配位的磺酸根阴离子。化合物1缓慢水解为[（n -C 4 H 9）2 Sn（μ-OH）（OSO 2 C 6 H 3（CH 3）2- 2，5）] 2（2保持在CH时）2氯2几天。晶体结构表明2具有二聚体结构，其中锡原子被两个羟基桥接，并且每个锡原子进一步键合至两个n- Bu基团和单配位的磺酸根阴离子，从而在锡原子处产生三角双锥体的几何形状。但是，如果还考虑到Sn与相邻磺酸根阴离子的O原子之间的2.6
• Unmasking endotoxins in solution
  申请人：Hyglos Invest GmbH

  公开号：EP2955518A1

  公开（公告）日：2015-12-16

  The invention relates to unmasking endotoxins in compositions so that previously present, but undetectable endotoxins are rendered detectable.

  本发明涉及揭开组合物中内毒素的面纱，使以前存在但无法检测到的内毒素变得可以检测到。
• METHOD OF SYNTHESIZING CONDUCTIVE POLYMER AND METHOD OF FABRICATING CONDUCTIVE POLYMER THIN FILM
  申请人：Pukyong National University Industry - University Cooperation Foundation

  公开号：EP4015560A1

  公开（公告）日：2022-06-22

  Proposed are a method of synthesizing a conductive polymer, a method of fabricating a conductive polymer thin film, and a functional film and an electronic device each including the conductive polymer thin film fabricated thereby. The method of synthesizing the conductive polymer includes the steps of: (a) preparing a PSS dispersion containing poly (styrene sulfonic acid) (PSS); and (b) preparing a conductive polymer containing poly(3,4-ethylenedioxythiophene):poly(styrenesulfonic acid) (PEDOT:PSS) by allowing a reaction of a mixture containing the PSS dispersion, a 3,4-ethylenedioxythiophene (EDOT) monomer, and an oxidizing agent. At least one of the PSS dispersion of step (a) and the mixture of step (b) further includes at least one selected from the group consisting of a metal nanomaterial and a metal nanomaterial precursor.

  本发明提出了一种合成导电聚合物的方法、一种制造导电聚合物薄膜的方法，以及一种功能薄膜和一种电子设备，每种功能薄膜和电子设备都包括由此制造的导电聚合物薄膜。合成导电聚合物的方法包括以下步骤(a) 制备含有聚（苯乙烯磺酸）（PSS）的 PSS 分散体；以及 (b) 通过使含有 PSS 分散体、3,4-亚乙二氧基噻吩（EDOT）单体和氧化剂的混合物发生反应，制备含有聚（3,4-亚乙二氧基噻吩）:聚（苯乙烯磺酸）（PEDOT:PSS）的导电聚合物。步骤(a)的 PSS 分散液和步骤(b)的混合物中的至少一种还包括选自金属纳米材料和金属纳米材料前体的至少一种。
• Avibactam free acid
  申请人：Sandoz AG

  公开号：US11124513B2

  公开（公告）日：2021-09-21

  The present invention relates to avibactam free acid, a method for preparing avibactam free acid and a method for preparing avibactam sodium by further reacting avibactam free acid. The invention further refers to a pharmaceutical composition comprising avibactam free acid, one or more alkaline sodium salt(s) and one or more beta-lactam antibiotic(s). The pharmaceutical composition of the present invention can be used as medicament, in particular for treatment and/or prevention of bacterial infections.

  本发明涉及阿维菌素游离酸、制备阿维菌素游离酸的方法和通过进一步反应阿维菌素游离酸制备阿维菌素钠的方法。本发明还涉及一种药物组合物，其中包括阿维菌素游离酸、一种或多种碱性钠盐和一种或多种β-内酰胺类抗生素。本发明的药物组合物可用作药物，特别是用于治疗和/或预防细菌感染。