3-[benzyl-[(1R)-1-phenylethyl]amino]propanoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-[benzyl-[(1R)-1-phenylethyl]amino]propanoic acid
• 化学式: C₁₈H₂₁NO₂
• 分子量: 283.4
• InChiKey: WJUZRYXHNJPCSY-OAHLLOKOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  21
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] NONANOIC AND DECANOIC ACID DERIVATIVES AND USES THEREOF<br/>[FR] DÉRIVÉS D'ACIDE NONANOÏQUE ET DÉCANOÏQUE ET LEURS UTILISATIONS
  申请人：SCIFLUOR LIFE SCIENCES INC

  公开号：WO2017189828A1

  公开（公告）日：2017-11-02

  The present disclosure relates to fluorinated compounds of formula (I) and methods of synthesizing these compounds. The present disclosure also relates to pharmaceutical compositions containing the fluorinated compounds of the disclosure, and methods of treating fibrosis, macular degeneration, diabetic retinopathy (DR), macular edema, diabetic macular edema (DME), and macular edema following retinal vein occlusion (RVO), by administering these compounds and pharmaceutical compositions to subjects in need thereof.