lithium N-propanoate-N,N-bis(2-pyridylmethyl)amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: lithium N-propanoate-N,N-bis(2-pyridylmethyl)amine
• 英文别名: LiPBMPA；Lithium;3-[bis(pyridin-2-ylmethyl)amino]propanoate；lithium;3-[bis(pyridin-2-ylmethyl)amino]propanoate
• 化学式: C₁₅H₁₆N₃O₂*Li
• 分子量: 277.252
• InChiKey: WPVCKDWPJJEEEN-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -2.38
• 重原子数：
  21
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  69.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  lithium N-propanoate-N,N-bis(2-pyridylmethyl)amine 、 cobalt(II) chloride 以 甲醇 为溶剂， 反应 4.0h， 以81%的产率得到Co^II(PBMPA)Cl
  参考文献：
  名称：

  Transition metal complexes bearing flexible N3 or N3O donor ligands: Reactivity toward superoxide radical anion and hydrogen peroxide

  摘要：

  Mononuclear complexes of N-methylpropanoate-N,N-bis-(2-pyridylmethyl)amine (MPBMPA) and N-propanoate-N,N-bis-(2-pyridylmethyl)amine (HPBMPA) with first row transition metals from Mn to Cu were synthesized and characterized by spectroscopy (infrared, UV-visible), electrochemistry (cyclic voltammetry), microanalysis and in four cases X-ray crystallography. Structure of the complexes revealed high flexibility of these ligands that can adopt facial (Fe) and meridional (Cu) geometry. Activity in the degradation of reactive oxygen species (superoxide radical anion: superoxide dismutase (SOD)-like activity and hydrogen peroxide: catalase-like activity) was tested throughout the complex series in aqueous solutions. In connection with the catalytic dismutation of H2O2, bleaching tests with morin were also conducted in water. Comparison of the two ligands helped in elucidating the possible role of the carboxylate moiety in the different catalytic reactions. Although no general trends could be revealed between reactivity and constitution of the first coordination sphere, plausible explanations for differences are discussed individually for SOD like, catalase-like and bleaching activity. (C) 2012 Elsevier Inc. All rights reserved.

  DOI：

  10.1016/j.jinorgbio.2012.08.012
• 作为产物：
  描述：

  N-(methyl propanoate)-N,N-bis-(2-pyridylmethyl)amine 在 lithium hydroxide 作用下， 以 甲醇 为溶剂， 生成 lithium N-propanoate-N,N-bis(2-pyridylmethyl)amine
  参考文献：
  名称：

  Photocatalytic degradation of dyes by mononuclear copper(II) complexes from bis-(2-pyridylmethyl)amine NNN-derivative ligands

  摘要：

  Photocatalytic degradation of organic pollutant dyes under ultraviolet radiation has emerged as an efficient wastewater treatment. This work describes the application of four mononuclear copper(II) complexes co-ordinated to NNN ligands: bis-(2-pyridylmethyl)amine (BMPA), N-methylpropanoate-N,N-bis-(2-pyridylmethyl) amine (MPBMPA), N-propanoate-N,N-bis-(2-pyridylmethyl)amine (PBMPA) and N-propanamide-N,N-bis-(2-pyridylmethyl)amine (PABMPA); in the photocatalytic degradation of different dyes: methyl orange (MO), methylene blue (MB), crystal violet (CV), Congo red (CR) and Rhodamine B (RhB). The reactions were carried out under a UV lamp of 250 W, where 100% of degradation was achieved in 90 min for all complexes using hydrogen peroxide as oxidant. Kinetic experiments were carried out to investigate the photodegradation of the dyes under a UV lamp of 24 W. The reactions followed a zero-order model in relation to the dye, showing that its concentration did not play a significant role in the photocatalysis. The reaction order in relation to hydrogen peroxide varied from 0 to 0.8, from low to high concentrations of oxidant. The light intensity and the intrinsic catalytic activity of the complexes are the most important features for the dye photodegradation pathway.

  DOI：

  10.1016/j.ica.2020.119924

文献信息

• Synthesis, characterization, X-ray molecular structure and catalase-like activity of a non-heme iron complex: Dichloro[N-propanoate-N,N-bis-(2-pyridylmethyl)amine]iron(III)
  作者：Nakédia M.F. Carvalho、Adolfo Horn、Roberto B. Faria、Adailton J. Bortoluzzi、Valderes Drago、O.A.C. Antunes

  DOI：10.1016/j.ica.2006.06.021

  日期：2006.10

  Abstract In this work we present the synthesis and characterization of the complex dichloro[N-propanoate-N,N-bis-(2-pyridylmethyl)amine]iron(III) [FeIII(PBMPA)Cl2]. The ligand LiPBMPA was synthesized through the Michael reaction of BMPA with methylacrylate, followed by alkaline hydrolysis. The complex [FeIII(PBMPA)Cl2] has been synthesized by the reaction of the ligand with FeCl3 · H2O and was mainly

  摘要在这项工作中，我们介绍了二氯[N-丙酸酯-N，N-双-（2-吡啶基甲基）胺]铁（III）[FeIII（PBMPA）Cl2]的合成和表征。配体LiPBMPA是通过BMPA与丙烯酸甲酯的迈克尔反应，然后进行碱水解而合成的。通过配体与FeCl3·H2O的反应合成了[FeIII（PBMPA）Cl2]配合物，其主要特征在于循环伏安法，电导法，电子，红外和莫斯鲍尔分光光度法以及X射线结构分析，表明一个由一个羧酸单氧，一个叔胺，两个吡啶基和两个氯离子配位的铁中心。已经提出，在水中氯化物配体被溶剂分子移动，并且种类[FeIII（PBMPA）（ ）2] Cl2是主要的。在水中测试了该复合物的过氧化氢酶样活性，并证明其在过氧化氢歧化中具有活性。动力学研究是按照初始速率法进行的。该反应对于络合物和过氧化氢都是一级的。基于依赖于初始复合物浓度的滞后阶段的存在，我们建议显示原位过氧化氢酶样活性的活性物质是双核复合物。