2-(3-bromophenoxy)-N-(3-methylphenyl)acetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(3-bromophenoxy)-N-(3-methylphenyl)acetamide
• 化学式: C₁₅H₁₄BrNO₂
• mdl: MFCD02172594
• 分子量: 320.18
• InChiKey: XZLFYOXWFNWHOM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.133
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES
  申请人：BASSLER Bonnie L.

  公开号：US20160368892A1

  公开（公告）日：2016-12-22

  Antivirulence strategies to combat Pseudomonas aeruginosa , are described. One strategy encompasses synthesis of a series of compounds that inhibit the production of pyocyanin, a redox-active virulence factor produced by this pathogen. A related strategy encompasses synthesis of compounds that inhibit the two P. aeruginosa quorum-sensing receptors, LasR and RhlR, inhibit production of pyocyanin, and inhibit biofilm formation.
• US9751851B2
  申请人：——

  公开号：US9751851B2

  公开（公告）日：2017-09-05