N¹-butyl-4-methyl-m-phenylenediamine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N¹-butyl-4-methyl-m-phenylenediamine
• 英文别名: 2-Amino-4-butylamino-toluol；N¹-Butyl-4-methyl-m-phenylendiamin；1-N-butyl-4-methylbenzene-1,3-diamine
• 化学式: C₁₁H₁₈N₂
• 分子量: 178.277
• InChiKey: QHZLHUNCGDBYTR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  38
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N-butyl-4-methyl-3-nitro-aniline 在 盐酸 、 锌 作用下， 生成 N¹-butyl-4-methyl-m-phenylenediamine
  参考文献：
  名称：

  Reilly; Hickinbottom, Journal of the Chemical Society, 1919, vol. 115, p. 178

  摘要：

  DOI：

文献信息

• Efficient nickel-catalysed<i>N</i>-alkylation of amines with alcohols
  作者：Anastasiia Afanasenko、Saravanakumar Elangovan、Marc C. A. Stuart、Giuseppe Bonura、Francesco Frusteri、Katalin Barta

  DOI：10.1039/c8cy01200h

  日期：——

  selective N-alkylation of amines with alcohols, that is in situ generated from Ni(COD)2 and KOH under ligand-free conditions. This novel method is very efficient for the functionalization of aniline and derivatives with a wide range of aromatic and aliphatic alcohols as well as diols and exhibits excellent functional group tolerance including halides, benzodioxane and heteroaromatic groups. Several TEM measurements

  通过借用氢策略使胺与醇选择性地进行N烷基化反应是一种突出的可持续催化方法，该方法产生水作为唯一的副产物，非常适合可广泛衍生自可再生能源的醇反应伙伴的催化转化资源。集中研究致力于开发主要基于昂贵的贵金属的新型催化剂。但是，用于这种转化的均相或非均相非贵金属催化剂的可用性非常有限。本文中，我们提出了一种高活性且非常易于制备的镍基催化剂体系，用于将胺与醇选择性地进行N-烷基化，该反应是就地进行的。在无配体条件下由Ni（COD）2和KOH生成。这种新方法对于苯胺及其衍生物与各种芳香族和脂肪族醇以及二醇的官能化非常有效，并且具有出色的官能团耐受性，包括卤化物，苯并二恶烷和杂芳族基团。为了结合活性催化剂的性质和影响反应活性的因素，进行了几种TEM测量和元素分析的结合。
• [EN] COMPOSITION FOR USE IN FLEXIBLE POLYURETHANE FOAMS<br/>[FR] COMPOSITION UTILISABLE DANS DES MOUSSES SOUPLES DE POLYURETHANE
  申请人：SOLUTIA INC

  公开号：WO2000073368A1

  公开（公告）日：2000-12-07

  A plasticizer with a crosslinking/chain extending agent is incorporated into a water-blown flexible polyurethane foam formulation to provide acceptable softness, openness, and tensile strength characteristics. The class of plastisizers is selected from the group consisting of alkyl benzyl phthalates, phosphate esters and benzoates. The aromatic pholyhydroxy compounds are a preferred class of crosslinking/chain extending agents, particularly dihydroxyaromatic compounds, more particularly resorcinol. Other classes of preferred crosslinking/extending agents are saccharides, alkyl glycosides, and alkylene oxide adducts of aliphatic triols. Other preferred crosslinker/extenders include epoxidized soybean oil, polymeric 1,3,5-trimethyl,2-hydroxy-benzene, selected phenolic resins, selected low molecular weight adducts of a polyfunctional aliphatic amines, and polyoxyalkylene polyols wherein the hydroxyl number is less than about 200 and the average number of hydroxyl groups range from about 3 to about 8.
• Reilly; Hickinbottom, Journal of the Chemical Society, 1919, vol. 115, p. 178
  作者：Reilly、Hickinbottom

  DOI：——

  日期：——