lithium 2,5-dihydroxybenzoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: lithium 2,5-dihydroxybenzoate
• 英文别名: Lithium;3-carboxy-4-hydroxyphenolate；lithium;3-carboxy-4-hydroxyphenolate
• 化学式: C₇H₅O₄*Li
• 分子量: 160.055
• InChiKey: JWJQXDRUZXWVQB-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -3.53
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  80.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2,5-二羟基苯甲酸 在 lithium carbonate 作用下， 以 水 为溶剂， 生成 lithium 2,5-dihydroxybenzoate
  参考文献：
  名称：

  New MALDI matrices based on lithium salts for the analysis of hydrocarbons and wax esters

  摘要：

  合成了有机芳香酸的锂盐（苯甲酸锂、水杨酸锂、香草酸锂、2,5-二甲氧基苯甲酸锂、2,5-二羟基对苯二甲酸锂、α-氰基-4-羟基肉桂酸锂和山奈酸锂），作为基质辅助激光解吸/电离（MALDI）的潜在基质进行了测试、合成了α-氰基-4-羟基肉桂酸锂和α-氰基-4-羟基肉桂酸锂），并将其作为基质辅助激光解吸/电离（MALDI）质谱分析碳氢化合物和蜡酯的潜在基质进行了测试。使用氮激光（337.1 nm）对分析物进行解吸，并通过锂阳离子的附着进行电离，生成 [M + Li]+ 加合物。使用硬脂基山嵛酸酯和正三烷基标准品对每种基质的样品制备和实验条件进行了优化。研究了新基质在信号强度和重现性、基质离子所占质量范围以及激光功率阈值等方面的性能，并将其与之前推荐的 2,5-二羟基苯甲酸锂基质（LiDHB）进行了比较（Cvačka 和 Svatoš，Rapid Commun. Mass Spectrom.）有几种新基质的性能优于 LiDHB。香草酸锂对蜡酯和碳氢化合物的信号分别高出 2-3 倍和 7-9 倍。同时，信号的重现性也大大提高，因此这种基质适合成像应用。此外，还对合成化合物的漫反射光谱和溶解性进行了研究，并讨论了化合物作为 MALDI 基质的能力。在蜡酯和碳氢化合物的天然样品上测试了所选基质的适用性。Copyright © 2014 John Wiley & Sons, Ltd. All Rights Reserved.

  DOI：

  10.1002/jms.3384

文献信息

• COMBINATION THERAPY
  申请人：Follica, Inc.

  公开号：EP2552323A1

  公开（公告）日：2013-02-06
• HAIR GROWTH TREATMENT
  申请人：LEDERMAN Seth M.

  公开号：US20110130711A1

  公开（公告）日：2011-06-02

  The present disclosure provides methods and systems for increasing hair growth in subjects in need thereof due to male- or female-pattern hair loss, pathological hair loss, or hair loss after injury. By any use of any appropriate mechanical, electromagnetic, or chemical means, the present disclosure pertains to the segmentation of hair follicles into two or more disunited subunits in order to form new follicles from the respective subunits. In contrast with known techniques for bisecting hair follicles and as described more fully herein, the present methods and systems permit the bisection of single follicles or populations of follicles with a high degree of efficiency, and thereby represent an effective treatment option for those in need of increased hair growth.
• SEQUENTIAL BODY SURFACE TREATMENT
  申请人：KELLOGG Scott C.

  公开号：US20110130706A1

  公开（公告）日：2011-06-02

  The present methods and systems provide treatment of a preselected body surface by injuring a portion of the body surface, optionally applying a composition such as a pharmaceutical agent to the injured portion of the body surface, and selection of a further portion on the body surface for the same or different injury and optional contacting with the same or different composition, wherein the further portion has a preselected geometry with respect to the first injured portion. The repetition of the selection, injury, and optional exposure to a composition with respect to successive portions of the body surface, optionally under partial or total computer control, provides efficient treatment of the body surface pursuant to the objective of regeneration, remodeling, resurfacing, restoration, follicular neogenesis, neocollagenesis, stem cell recruitment, activation, or differentiation, reepitheliazation, wound healing, or any other desired biological or physical modification.
• BODY SURFACE TREATMENT
  申请人：KELLOGG Scott C.

  公开号：US20110130748A1

  公开（公告）日：2011-06-02

  The present methods and systems provide the induction of preselected injury types to target areas of tissue in an iterative manner in order to provide beneficial treatment with respect to a desired body surface. The methods and systems disclosed herein may include the precise selection of target areas for treatment, which may itself involve identifying physical features that require treatment, distinguishing areas or features that are not suitable for treatment, or both. The present modalities are distinguishable from prior methodologies having lower rates of success because of the failure of the latter to match treatment or treatment type with specific physical features.
• COMPOSITION CONTAINING LANTHANIDE METAL COMPLEX
  申请人：RHODIA OPERATIONS

  公开号：US20210179975A1

  公开（公告）日：2021-06-17

  Provided is the use of a lanthanide metal complex as a bleaching catalyst. In particular, the lanthanide metal complex comprises a ligand which is an aromatic compound having at least one electron withdrawing substituent and at least one nucleophilic group. Provided is also a composition containing the lanthanide metal complex.