Ammonium nicotinate | 36321-41-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: Ammonium nicotinate
• 英文别名: 3-Pyridinecarboxylic acid, ammonium salt；azane;pyridine-3-carboxylic acid
• CAS: 36321-41-2
• 化学式: C₆H₈N₂O₂
• 分子量: 140.142
• InChiKey: ONJIBHRZSUEBDS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.18
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  54
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  Ammonium nicotinate 以19%的产率得到3-氰基吡啶
  参考文献：
  名称：

  Gas-chromatographic analysis of pyridinecarboxylic acids on the basis of their pyrolysis products

  摘要：

  DOI：

  10.1007/bf00765394

文献信息

• Process for conversion of cyanopyridines to nicotinamides and catalyst therefor, process for preparing said catalyst
  申请人：——

  公开号：US20040186297A1

  公开（公告）日：2004-09-23

  The present invention relates to an improved process for conversion of cyanopyridines to nicotinamides More particularly the present invention relates to preparation of nicotinamides and isonicotinamides which finds its usage in the preparation of anti-TB drug i.e. isoniazid and as an intermediate of vitamin B 12 . The present invention also relates to a process for a catalyst useful for the preparation of nicotinamide and isonicotinamide.

  本发明涉及一种改进的过程，用于将氰基吡啶转化为烟酰胺。更具体地，本发明涉及烟酰胺和异烟酰胺的制备，用于制备抗结核药物异烟肼以及作为维生素B12的中间体的用途。本发明还涉及一种催化剂的制备过程，该催化剂对于烟酰胺和异烟酰胺的制备是有用的。
• [EN] PROCESS FOR CONVERSION OF CYANOPYRIDINES TO NICOTINAMIDES AND CATALYST THEREFOR, PROCESS FOR PREPARING SAID CATALYST<br/>[FR] PROCEDE DE CONVERSION DE CYANOPYRIDINES EN NICOTINAMIDES ET CATALYSEUR ASSOCIE, ET PROCEDE POUR LA PREPARATION DUDIT CATALYSEUR
  申请人：COUNCIL SCIENT IND RES

  公开号：WO2004056776A1

  公开（公告）日：2004-07-08

  The present invention relates to an improved process for conversion of cyanopyridines to nicotinamides. More particularly the present invention relates to preparation of nicotinamides and isonicotinamides which finds its usage in the preparation of anti-TB drug i.e. isoniazid and as an intermediate of vitamin B12. The present invention also relates to a process for a catalyst useful for the preparation of nicotinamide and isonicotinamide.

  本发明涉及一种改进的氰基吡啶转化为烟酰胺的方法。更具体地，本发明涉及制备烟酰胺和异烟酰胺，这在制备抗结核药物即异烟肼和作为维生素B12的中间体中有用。本发明还涉及一种催化剂的制备方法，可用于制备烟酰胺和异烟酰胺。
• Continuous Method For Producing Amides of Aromatic Carboxylic Acids
  申请人：Krull Matthias

  公开号：US20110089019A1

  公开（公告）日：2011-04-21

  The invention relates to a continuous method for producing amides of aromatic carboxylic acids, according to which at least one aromatic carboxylic acid of formula (I) Ar—COON   (I) wherein Ar is an optionally substituted aryl radical comprising between 5 and 50 atoms, is reacted with at least one amine of formula (II) HNR 1 R 2 (II) wherein R 1 and R 2 are independently hydrogen or a hydrocarbon radical comprising between 1 and 100 C atoms, to form an ammonium salt, and said ammonium salt is then reacted to form a carboxylic acid amide, under microwave irradiation in a reaction pipe, the longitudinal axis of the pipe being oriented in the direction of propagation of the microwaves of a monomode microwave applicator.

  该发明涉及一种连续生产芳香羧酸酰胺的方法，根据该方法，将式(I)Ar—COON中的至少一种芳香羧酸（其中Ar是一个可选择取代的含有5至50个原子的芳基基团）与式(II)HNR1R2中的至少一种胺（其中R1和R2独立地是氢或含有1至100个碳原子的烃基团）反应，形成铵盐，然后将所述铵盐反应形成羧酸酰胺，在一个反应管中通过微波辐射，管的纵轴沿着单模微波应用器的微波传播方向定向。
• METHOD OF PRODUCING A METAL PHTHALOCYANINE COMPOUND, AND METHOD OF PRODUCING A PHTHALOCYANINE COMPOUND AND AN ANALOGUE THEREOF
  申请人：Tateishi Keiichi

  公开号：US20090247742A1

  公开（公告）日：2009-10-01

  A method of producing a metal phthalocyanine compound, which contains: conducting a reaction between at least two compounds selected from among Compounds A to F of formula (I), and a metal compound, in a buffer solution of an organic base or an inorganic base and an acid, in the presence of a dehydrating agent: wherein R is a hydrogen atom or a substituent; l is an integer of 0 to 4; a plurality of Rs may be the same or different from each other when l is 2 to 4; and G is a group of atoms necessary for forming at least one of a 5- or 6-membered aromatic ring and a 5- or 6-membered hetero ring.

  生产金属酞菁化合物的方法，包括：在有机碱或无机碱和酸的缓冲溶液中，在脱水剂的存在下，将公式（I）中的至少两种化合物A至F和金属化合物反应，其中R是氢原子或取代基；l是0到4的整数；当l为2到4时，多个R可以相同或不同；G是必要的原子团，用于形成5或6元芳香环和5或6元杂环中的至少一个。
• Catalytic Process for Production of Pyridine Carboxylic Acid Amides
  申请人：Kumar Mahendra

  公开号：US20140081029A1

  公开（公告）日：2014-03-20

  An improved catalytic process for the production of pyridine carboxylic acid amides, by catalytic hydration reaction of pyridine nitriles with solid heterogeneous catalyst wherein the process involve effective utilization and recycling of the catalytic components, and reactants.

  一种改进的催化过程，用于生产吡啶羧酸酰胺，通过将吡啶腈与固体杂化催化剂进行催化水合反应，其中过程涉及催化组分和反应物的有效利用和循环利用。