(25R)-26-O-[β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl]-5-ene-furost-1β,3β,22α,26-tetraol-3-O-α-L-rhamnopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→4)]-β-D-glucopyranoside

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (25R)-26-O-[β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl]-5-ene-furost-1β,3β,22α,26-tetraol-3-O-α-L-rhamnopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→4)]-β-D-glucopyranoside
• 英文别名: ophiopogonin Q；(2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-2-[[(1S,2S,4S,6R,7S,8R,9S,12S,13R,14R,16R)-6-[(3R)-4-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3-methylbutyl]-6,14-dihydroxy-7,9,13-trimethyl-5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-en-16-yl]oxy]-4-hydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol
• 化学式: C₅₆H₉₂O₂₈
• 分子量: 1213.33
• InChiKey: FZDWHXOKCCEOTM-VOHXEBEJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.8
• 重原子数：
  84
• 可旋转键数：
  17
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  445
• 氢给体数：
  17
• 氢受体数：
  28

反应信息

• 作为反应物：
  描述：

  (25R)-26-O-[β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl]-5-ene-furost-1β,3β,22α,26-tetraol-3-O-α-L-rhamnopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→4)]-β-D-glucopyranoside 在 三氟乙酸 作用下， 以 水 为溶剂， 反应 4.0h， 生成 D-木糖 、 L-鼠李糖 、 葡萄糖
  参考文献：
  名称：

  Two novel furostanol saponins from the tubers ofOphiopogon japonicus

  摘要：

  Phytochemical investigation of the fresh tubers of Ophiopogon japonicus led to the isolation of two new furostanol saponins (1 and 2) together with two known steroidal saponins (3 and 4). Comprehensive spectroscopic analysis allowed the chemical structures of two new compounds to be elucidated as (25R)-26-O-[-d-glucopyranosyl-(12)--d-glucopyranosyl]-5-ene-furost-1,3,22,26-tetraol-3-O--l-rhamnopyranosyl-(12)-[-d-xylopyranosyl-(14)]--d-glucopyranoside (1, ophiopogonin P) and (25R)-26-O-[-d-glucopyranosyl-(16)--d-glucopyranosyl]-5-ene-furost-1,3,22,26-tetraol-3-O--l-rhamnopyranosyl-(12)-[-d-xylopyranosyl-(14)]--d-glucopyranoside (2, ophiopogonin Q). Furostanol saponins with the disaccharide chain linked at C-26 hydroxy group of the aglycone have been rarely reported from natural sources.

  DOI：

  10.1080/10286020.2013.783024

文献信息

• Two novel furostanol saponins from the tubers of<i>Ophiopogon japonicus</i>
  作者：Yu Guo、Yi-Xun Liu、Li-Ping Kang、Tao Zhang、He-Shui Yu、Yang Zhao、Cheng-Qi Xiong、Bai-Ping Ma

  DOI：10.1080/10286020.2013.783024

  日期：2013.5

  Phytochemical investigation of the fresh tubers of Ophiopogon japonicus led to the isolation of two new furostanol saponins (1 and 2) together with two known steroidal saponins (3 and 4). Comprehensive spectroscopic analysis allowed the chemical structures of two new compounds to be elucidated as (25R)-26-O-[-d-glucopyranosyl-(12)--d-glucopyranosyl]-5-ene-furost-1,3,22,26-tetraol-3-O--l-rhamnopyranosyl-(12)-[-d-xylopyranosyl-(14)]--d-glucopyranoside (1, ophiopogonin P) and (25R)-26-O-[-d-glucopyranosyl-(16)--d-glucopyranosyl]-5-ene-furost-1,3,22,26-tetraol-3-O--l-rhamnopyranosyl-(12)-[-d-xylopyranosyl-(14)]--d-glucopyranoside (2, ophiopogonin Q). Furostanol saponins with the disaccharide chain linked at C-26 hydroxy group of the aglycone have been rarely reported from natural sources.