(2,3,4-trimethoxy-phenyl)-(3,4,5-trimethoxy-phenyl)-methane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2,3,4-trimethoxy-phenyl)-(3,4,5-trimethoxy-phenyl)-methane
• 英文别名: (2,3,4-Trimethoxy-phenyl)-(3,4,5-trimethoxy-phenyl)-methan；1,2,3-Trimethoxy-4-[(3,4,5-trimethoxyphenyl)methyl]benzene
• 化学式: C₁₉H₂₄O₆
• 分子量: 348.396
• InChiKey: ONBQEBQAMYHMRX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  25
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  55.4
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  1,2,3-三甲氧基苯 、 3,4,5-三甲氧基甲苯 在 溴 作用下， 以 四氯化碳 为溶剂， 以40%的产率得到(2,3,4-trimethoxy-phenyl)-(3,4,5-trimethoxy-phenyl)-methane
  参考文献：
  名称：

  One‐Step Synthesis of Diphenylmethanes

  摘要：

  The coupling reaction of substituted toluenes themselves and the cross-coupling reaction of substituted toluene and aromatic in the presence of bromine in anhydrous CCl4 under irradiation lead to diphenylmethanes with moderate to good yields. The methylene moiety in diphenylmethanes comes from the toluene with fewer electron-donating groups, and regioselectivity was observed.

  DOI：

  10.1081/scc-200050959

文献信息

• Richtzenhain, Chemische Berichte, 1944, vol. 77/79, p. 409,416
  作者：Richtzenhain

  DOI：——

  日期：——
• One‐Step Synthesis of Diphenylmethanes
  作者：Qiyan Wei、Yinggang Luo、Min Zhou、Feiyan Tao、Guoling Zhang

  DOI：10.1081/scc-200050959

  日期：2005.3

  The coupling reaction of substituted toluenes themselves and the cross-coupling reaction of substituted toluene and aromatic in the presence of bromine in anhydrous CCl4 under irradiation lead to diphenylmethanes with moderate to good yields. The methylene moiety in diphenylmethanes comes from the toluene with fewer electron-donating groups, and regioselectivity was observed.