4-[2-(3-Chlorophenyl)ethylamino]-3-nitrobenzaldehyde

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-[2-(3-Chlorophenyl)ethylamino]-3-nitrobenzaldehyde
• 化学式: C15H13ClN2O3
• 分子量: 304.73
• InChiKey: WCZXOAMBOXKNNG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  74.9
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• USE OF ORGANIC COMPOUNDS FOR IMMUNOPOTENTIATION
  申请人：CHIRON CORPORATION

  公开号：EP1608369A2

  公开（公告）日：2005-12-28
• [EN] USE OF SMALL MOLECULE COMPOUNDS FOR IMMUNOPOTENTIATION<br/>[FR] UTILISATION DE PETITES MOLECULES DE COMPOSES POUR UNE IMMUNOPOTENTIALISATION
  申请人：CHIRON CORP

  公开号：WO2004087153A2

  公开（公告）日：2004-10-14

  The invention provides immunostimulatory compositions comprising a small molecule immuno-poteniator (SMIP) compound and methods of administration thereof. Also provided are methods of administering a SMIP compound in an effective amount to enhance the immune response of a subject to an antigen. Further provided are novel compositions and methods of administering SMIP compounds alone or in combination with another agent for the treatment of cancer, infectious diseases and/or allergies/asthma.