ethyl 2-{4-[N-methyl-N-(6-chloro-2-benzoxazolyl)amino]phenoxy}propionate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: ethyl 2-{4-[N-methyl-N-(6-chloro-2-benzoxazolyl)amino]phenoxy}propionate
• 英文别名: Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)-methylamino]phenoxy]propanoate
• 化学式: C₁₉H₁₉ClN₂O₄
• 分子量: 374.824
• InChiKey: HFFBGMVVBSQIHX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  26
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  64.8
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  对甲氨基酚 以 乙醇 为溶剂， 生成 ethyl 2-{4-[N-methyl-N-(6-chloro-2-benzoxazolyl)amino]phenoxy}propionate
  参考文献：
  名称：

  -Methyl as a bioisostere for the oxygen link between the aromatic rings of aryloxyphenoxypropionate herbicides

  摘要：

  The herbicidal activity of a set of (N) under bar,methyl arylaminophenoxypropionate esters 3 has been compared to the analogous aryloxyphenoxypropionates 1. The usefulness of (N) under bar-methyl as a novel bioisostere for ether links is shown by the surprisingly high herbicidal activity of the 6-chloroquinazolin-2-yl- and 7-chloro-1,2,4-benzotriazin-3-yl-N-methylamino-phenoxypropionate esters 3h and 3i. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0960-894x(97)00235-7

文献信息

• Herbicidal compounds, their preparation, compositions and process for the use thereof
  申请人：ICI AUSTRALIA LIMITED

  公开号：EP0018080A1

  公开（公告）日：1980-10-29

  Diarylamine derivatives of formula I wherein φ is chosen from in which Z is chosen from O. S, NH and N-C1-C6 alkyl. The compounds are herbicides and in further embodi ments the invention provides herbicidal compositions con taining as active ingredient a compound of formula I, process for severely damaging or killing unwanted plant by applying to the plants or to the growth medium of the plants an effective amount of a compound of formula processes for the preparation of compounds of formula and intermediates useful in the preparation of compound of formula 1.

  式 I 的二乙胺衍生物 其中φ选自 其中 Z 选自 O、S、NH 和 N-C1-C6 烷基。 本发明的化合物是除草剂，在进一步的实施方案中，本发明提供了含有作为活性成分的式 I 化合物的除草组合物，通过向植物或植物的生长介质施用有效量的式化合物来严重损害或杀死不需要的植物的工艺，以及制备式化合物和用于制备式 1 化合物的中间体的工艺。
• -Methyl as a bioisostere for the oxygen link between the aromatic rings of aryloxyphenoxypropionate herbicides
  作者：Graham J. Bird、Lindsay E. Cross、Graeme J. Farquharson、Wendy A. Jensen、Jack Lydiate、Alexander Serban、Richard B. Warner、Keith G. Watson、John E.D. Barton、Chris Coles、David J. Collins、John W. Slater

  DOI：10.1016/s0960-894x(97)00235-7

  日期：1997.6

  The herbicidal activity of a set of (N) under bar,methyl arylaminophenoxypropionate esters 3 has been compared to the analogous aryloxyphenoxypropionates 1. The usefulness of (N) under bar-methyl as a novel bioisostere for ether links is shown by the surprisingly high herbicidal activity of the 6-chloroquinazolin-2-yl- and 7-chloro-1,2,4-benzotriazin-3-yl-N-methylamino-phenoxypropionate esters 3h and 3i. (C) 1997 Elsevier Science Ltd.