4-bromo-N-[(2R)-2-phenylpropyl]benzenesulfonamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-bromo-N-[(2R)-2-phenylpropyl]benzenesulfonamide
• 化学式: C₁₅H₁₆BrNO₂S
• 分子量: 354.3
• InChiKey: HLOAQCJCEKXILX-LBPRGKRZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  54.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Substituted aminoalkylamide derivatives as antagonists of follicle stimulating hormone
  申请人：——

  公开号：US20040092505A1

  公开（公告）日：2004-05-13

  The present invention is directed to a series of novel substituted aminoalkylamide derivatives, pharmaceutical compositions containing them and their use in the treatment of reproductive disorders and affective conditions. Further, the compounds of the invention are antagonists of follicle stimulating hormone, a hormone associated with the human reproductive system.

  本发明涉及一系列新颖的取代氨基烷酰胺衍生物，包括它们的药物组合物以及它们在治疗生殖障碍和情感疾病中的应用。此外，本发明的化合物是卵泡刺激素拮抗剂，一种与人类生殖系统相关的激素。
• SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE
  申请人：Ortho-McNeil Pharmaceutical, Inc.

  公开号：EP1244617B1

  公开（公告）日：2005-02-16
• US6583179B2
  申请人：——

  公开号：US6583179B2

  公开（公告）日：2003-06-24
• [EN] SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE<br/>[FR] DERIVES D'AMINOALKYLAMIDE SUBSTITUES UTILISES EN TANT QU'ANTAGONISTES DE L'HORMONE FOLLICULOSTIMULANTE
  申请人：ORTHO MCNEIL PHARM INC

  公开号：WO2001047875A1

  公开（公告）日：2001-07-05

  The present invention is directed to a series of novel substituted aminoalkylamide derivatives, pharmaceutical compositions containing them and their use in the treatment of reproductive disorders and affective conditions. Further, the compounds of the invention are antagonists of follicle stimulating hormone, a hormone associated with the human reproductive system.