2,3-dihydro-2-(1-methylethyl)-1H-perimidine

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2,3-dihydro-2-(1-methylethyl)-1H-perimidine
• 英文别名: 2-isopropyl-2,3-dihydro-1H-perimidine
• 化学式: C₁₄H₁₆N₂
• 分子量: 212.294
• InChiKey: VCZLBJGTFKYKNM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.66
• 重原子数：
  16.0
• 可旋转键数：
  1.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  24.06
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  2,3-dihydro-2-(1-methylethyl)-1H-perimidine 在 三(2,2'-联吡啶)钌II 作用下， 以 乙腈 为溶剂， 反应 24.0h， 以77%的产率得到2-isopropyl-6H-perimidin-6-one
  参考文献：
  名称：

  Visible light photoredox catalysis: aerobic oxidation of perimidines to perimidinones

  摘要：

  Aerobic oxidation of a series of 2,3-dihydro-1H-perimidines to the corresponding 4- and 6-perimidinones via visible light photoredox catalysis using Ru(bpy)(3)(2+) as a catalyst was reported. The scope and limitation of this oxidation were investigated and a possible photochemical mechanism was proposed. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2014.09.036
• 作为产物：
  描述：

  异丁醛 、 1,8-二氨基萘 在 ytterbium(III) triflate 作用下， 以 乙腈 为溶剂， 反应 24.0h， 以88%的产率得到2,3-dihydro-2-(1-methylethyl)-1H-perimidine
  参考文献：
  名称：

  Visible light photoredox catalysis: aerobic oxidation of perimidines to perimidinones

  摘要：

  Aerobic oxidation of a series of 2,3-dihydro-1H-perimidines to the corresponding 4- and 6-perimidinones via visible light photoredox catalysis using Ru(bpy)(3)(2+) as a catalyst was reported. The scope and limitation of this oxidation were investigated and a possible photochemical mechanism was proposed. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2014.09.036

文献信息

• US9738811B2
  申请人：——

  公开号：US9738811B2

  公开（公告）日：2017-08-22
• Visible light photoredox catalysis: aerobic oxidation of perimidines to perimidinones
  作者：Chun-Ku Wu、Teau-Jiuan Liou、Hao-Yi Wei、Pei-Shan Tsai、Ding-Yah Yang

  DOI：10.1016/j.tet.2014.09.036

  日期：2014.11

  Aerobic oxidation of a series of 2,3-dihydro-1H-perimidines to the corresponding 4- and 6-perimidinones via visible light photoredox catalysis using Ru(bpy)(3)(2+) as a catalyst was reported. The scope and limitation of this oxidation were investigated and a possible photochemical mechanism was proposed. (C) 2014 Elsevier Ltd. All rights reserved.