二硫酸酯 | 16057-15-1

• 分子结构分类: 无机化合物 - 均质非金属化合物 - 非金属氧阴离子化合物
• 中文名称: 二硫酸酯
• 英文名称: Disulfate ion
• 英文别名: sulfonato sulfate
• CAS: 16057-15-1
• 化学式: O7S2-2
• 分子量: 176.13
• InChiKey: VFNGKCDDZUSWLR-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -1.9
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  140
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  己烯雌酚 、 二硫酸酯 在 乙醚 、 水 、 氢氧化钾 、 mono-sulfate 、 吡啶 、 di-potassium 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以27 g of DES disulfate was obtained as the corresponding di-potassium salt的产率得到DES disulfate
  参考文献：
  名称：

  SULFESTROL FOR TREATING CANCER

  摘要：

  本发明涉及使用硫酸二乙基雌苯酚（Sulfestrol）治疗哺乳动物癌症的治疗或缓解方法。发明人意外地发现，Sulfestrol可以作为治疗哺乳动物癌症的有效药物。发明人还发现，即使以高剂量给予Sulfestrol，也不会引起严重的副作用。除了Sulfestrol的临床应用外，本发明还涉及包含Sulfestrol的口服剂量单位和含有Sulfestrol的静脉注射用无菌液体。

  公开号：

  US20150283108A1

文献信息

• 6-Aryl pyrido\x9b2,3-d! pyrimidines and naphthyridines for inhibiting
  申请人：——

  公开号：US05733913A1

  公开（公告）日：1998-03-31

  6-Aryl pyrido\x9b2,3-d!pyrimidines and naphthyridines are inhibitors of protein tyrosine kinase, and are thus useful in treating cellular proliferation mediated thereby. The compounds are especially useful in treating atherosclerosis, restenosis, psoriasis, as well as bacterial infections.

  6-Aryl pyrido\x9b2,3-d!pyrimidines和naphthyridines是蛋白酪氨酸激酶的抑制剂，因此对于通过其介导的细胞增殖的治疗非常有用。这些化合物在治疗动脉粥样硬化、再狭窄、牛皮癣以及细菌感染方面特别有用。
• PROCESS FOR PRODUCING AMMONIA AND SULFURIC ACID FROM A STREAM COMPRISING AMMONIUM SULFATE
  申请人：Curren Meredith

  公开号：US20080056983A1

  公开（公告）日：2008-03-06

  A process for producing ammonia and sulfuric acid from a stream comprising ammonium sulfate is provided. The process comprises the steps of heating the stream to produce ammonia and a decomposition product comprising one or more than one of a bisulfate salt, a pyrosulfate salt, or a combination thereof. The ammonia produced is recovered, and water is added to the decomposition product to produce a stream comprising the decomposition product. The stream comprising the decomposition product is processed by acid retardation to obtain a sulfuric acid stream and a stream comprising one or more than one sulfate salt.

  提供了一种从含硫酸铵的流中生产氨和硫酸的过程。该过程包括以下步骤：加热流以产生氨和分解产物，该分解产物包括一个或多个硫酸氢盐、焦硫酸盐或其组合物。回收所产生的氨，并向分解产物中加水以产生一个含有分解产物的流。通过酸滞后处理处理含有分解产物的流以获得硫酸流和一个或多个硫酸盐的流。
• 6-aryl naphthyridines for inhibiting protein tyrosine kinase mediated
  申请人：Warner-Lambert Company

  公开号：US05952342A1

  公开（公告）日：1999-09-14

  6-Aryl naphthyridines are inhibitors of protein tyrosine kinase, and are thus useful in treating cellular proliferation mediated thereby. The compounds are especially useful in treating atherosclerosis, restenosis, psoriasis, as well as bacterial infections.

  6-芳基萘啶是蛋白酪氨酸激酶的抑制剂，因此在治疗细胞增殖介导的疾病方面非常有用。这些化合物在治疗动脉粥样硬化、再狭窄、牛皮癣以及细菌感染方面尤其有用。
• Process for producing ammonia and sulfuric acid from a stream comprising ammonium sulfate
  申请人：Iogen Energy Corporation

  公开号：US07632479B2

  公开（公告）日：2009-12-15

  A process for producing ammonia and sulfuric acid from a stream comprising ammonium sulfate is provided. The process comprises the steps of heating the stream to produce ammonia and a decomposition product comprising one or more than one of a bisulfate salt, a pyrosulfate salt, or a combination thereof. The ammonia produced is recovered, and water is added to the decomposition product to produce a stream comprising the decomposition product. The stream comprising the decomposition product is processed by acid retardation to obtain a sulfuric acid stream and a stream comprising one or more than one sulfate salt.

  提供了一种从含硫酸铵流中生产氨和硫酸的工艺。该工艺包括以下步骤：加热该流以产生氨和分解产物，其中分解产物包括一种或多种硫酸氢盐、焦硫酸盐或其组合物。回收所产生的氨，向分解产物中加入水以产生含分解产物的流。通过酸滞后处理含分解产物的流，以获得硫酸流和含一种或多种硫酸盐的流。
• SULFESTROL FOR TREATING CANCER
  申请人：CHAMAELEO PHARMA BVBA

  公开号：US20150283108A1

  公开（公告）日：2015-10-08

  The invention relates to the use of Sulfestrol (diethylstilbestrol sulfate) in a method of curative or palliative treatment of cancer in a mammal. The inventors have unexpectedly found that Sulfestrol can suitably be employed as an effective drug in the treatment of cancer in mammals. The inventors have further discovered that Sulfestrol can be administered even in high dosages without giving rise to serious side effects. Besides the clinical use of Sulfestrol the present invention also relates to oral dosage units comprising Sulfestrol and to sterile liquids for intravenous administration that comprise Sulfestrol.

  本发明涉及使用硫酸二乙基雌苯酚（Sulfestrol）治疗哺乳动物癌症的治疗或缓解方法。发明人意外地发现，Sulfestrol可以作为治疗哺乳动物癌症的有效药物。发明人还发现，即使以高剂量给予Sulfestrol，也不会引起严重的副作用。除了Sulfestrol的临床应用外，本发明还涉及包含Sulfestrol的口服剂量单位和含有Sulfestrol的静脉注射用无菌液体。