亚德里亚霉素醇 | 141614-05-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 亚德里亚霉素醇
• 英文名称: 1-(2,4-Diamino-5-methylphenoxy)ethan-1-ol
• 英文别名: 1-(2,4-diamino-5-methylphenoxy)ethanol
• CAS: 141614-05-3
• 化学式: C₉H₁₄N₂O₂
• 分子量: 182.22
• InChiKey: FLLUGYZLYWNKPW-UHFFFAOYSA-N

物化性质

• 沸点：
  404.9±40.0 °C(Predicted)
• 密度：
  1.228±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  81.5
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Oxidative hair dye compositions
  申请人：Bristol-Myers Squibb Company

  公开号：EP0891765A2

  公开（公告）日：1999-01-20

  The invention provides compositions and methods for the oxidative coloring of human hair. The compositions of the invention contain as a primary dye intermediate a 1-(4-aminophenyl) pyrrolidine, or a cosmetically acceptable salt thereof. The compositions may also contain at least one other primary intermediate and conventional coupling compounds, in addition to an oxidizing agent and other components typically used in oxidative hair dye preparations. Preferred dye intermediates in the compositions of the invention include 1-(4-aminophenyl) pyrrolidine and 1-(4-amino-3-methylphenyl) pyrrolidine, or cosmetically acceptable salts thereof, which produce intense neutral colors when used in admixture with a suitable coupling agents, such as 3-aminophenol, in conventional hair dye base formulations.

  本发明提供了对人类头发进行氧化染色的组合物和方法。本发明的组合物含有 1-（4-氨基苯基）吡咯烷或其美容上可接受的盐作为初级染料中间体。除了氧化剂和氧化染发制剂中通常使用的其他成分外，组合物中还可能含有至少一种其他主中间体和常规偶联化合物。本发明组合物中优选的染料中间体包括 1-（4-氨基苯基）吡咯烷和 1-（4-氨基-3-甲基苯基）吡咯烷，或它们在化妆品上可接受的盐，当它们与合适的偶联剂（如 3-氨基苯酚）混合用于常规染发剂基料配方中时，可产生强烈的中性色。
• Novel Bis-(2,4-diaminophenoxy) benzenes and their use as coupling components in oxidative hair coloring compositions and methods
  申请人：Bristol-Myers Squibb Company

  公开号：EP0918051A1

  公开（公告）日：1999-05-26

  The invention provides compositions and methods containing novel bis-(2,4-diaminophenoxy) benzene coupling compounds, and cosmetically acceptable salts thereof, for use with conventional primary intermediate dye compounds and oxidizing agents for the oxidative coloring of human hair. The compositions of the invention may also contain other components typically used in oxidative hair dye preparations to impart intense and lasting coloration to hair.

  本发明提供了含有新型双-（2,4-二氨基苯氧基）苯偶联化合物及其美容上可接受的盐的组合物和方法，可与传统的初级中间染料化合物和氧化剂一起用于人类头发的氧化着色。本发明的组合物还可含有氧化染发制剂中通常使用的其他成分，以赋予头发浓烈持久的着色效果。
• Oxidative hair dye compositions and methods containing 1-(4-aminophenyl)-2-pyrrolidinemethanols
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：EP0962452A1

  公开（公告）日：1999-12-08

  The invention provides compositions and methods for the oxidative coloring of human hair. The compositions of the invention contain as a novel primary dye intermediate a 1-(4-aminophenyl)-2-pyrrolidinemethanol, or a cosmetically acceptable salt thereof. The compositions may also contain at least one other primary intermediate and conventional coupling compounds, in addition to an oxidizing agent and other components typically used in oxidative hair dye preparations. A preferred dye intermediate in the composition of the invention is 1-(4-aminophenyl)-2-pyrrolidinemethanol or cosmetically acceptable salts thereof, which produce intense black colors when used in admixture with a suitable coupling agents, such as 3-aminophenol, in conventional hair dye base formulations.

  本发明提供了对人类头发进行氧化着色的组合物和方法。本发明的组合物含有 1-（4-氨基苯基）-2-吡咯烷甲醇或其美容上可接受的盐作为新型初级染料中间体。除了氧化剂和氧化染发制剂中通常使用的其他成分外，本发明组合物还可能含有至少一种其他主中间体和常规偶联化合物。本发明组合物中优选的染料中间体是 1-（4-氨基苯基）-2-吡咯烷甲醇或其美容上可接受的盐，当与合适的偶联剂（如 3-氨基苯酚）混合用于传统的染发基料配方中时，可产生浓黑的颜色。
• Hair dyeing compositions containing 2-chloro- and 2,6-dichloro-4-aminophenol & phenylpyrazolones
  申请人：Bristol-Myers Squibb Company

  公开号：EP0951900A2

  公开（公告）日：1999-10-27

  The invention provides compositions and methods for the oxidative coloring of human hair. The compositions of the invention contain as a primary intermediate at least one aminophenol of the formulas: or a cosmetically acceptable salt thereof, and at least one pyrazolone coupler of the formulas: or a cosmetically acceptable salt thereof. The compositions may also contain one or more other primary intermediates and conventional coupling compounds, in addition to an oxidizing agent and other components typically used in oxidative hair dye preparations.

  本发明提供了对人类头发进行氧化着色的组合物和方法。本发明的组合物含有至少一种以下式子的氨基苯酚或其化妆品可接受的盐作为初级中间体，以及至少一种以下式子的吡唑酮偶联剂： 或其美容上可接受的盐，以及至少一种形式如下的吡唑酮偶联剂： 或其化妆品可接受的盐。除了氧化剂和氧化染发制剂中通常使用的其他成分外，组合物中还可能含有一种或多种其他初级中间体和常规偶联化合物。
• Oxidative hair dye compositions with conditioning and enhanced color deposition
  申请人：Bristol-Myers Squibb Company

  公开号：EP1048290A2

  公开（公告）日：2000-11-02

  This invention concerns oxidative, hair coloring compositions which color and condition hair, requiring lesser amounts of dye concentrations due to the presence of certain amphoteric, quaternized, conditioning polymers. The polymers contain repeating units from acrylic acid and methacrylamidopropyl trimethyl ammonium chloride, dimethyl diallyl ammonium chloride, or a mixture thereof.

  本发明涉及氧化型染发组合物，由于含有某些两性、季铵化、调理型聚合物，该组合物可对头发进行着色和调理，所需的染料浓度较低。这些聚合物含有丙烯酸和甲基丙烯酰胺丙基三甲基氯化铵、二甲基二烯丙基氯化铵或它们的混合物的重复单元。