potassium N,N-diallyl(trifluoroboratomethyl)amine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 硼酸衍生物
• 英文名称: potassium N,N-diallyl(trifluoroboratomethyl)amine
• 英文别名: Potassium;[bis(prop-2-enyl)amino]methyl-trifluoroboranuide
• 化学式: C₇H₁₂BF₃N*K
• 分子量: 217.083
• InChiKey: DGEVUWZJOVKZIX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.95
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  (溴甲基)三氟硼酸钾 、 二烯丙基胺 反应 0.5h， 以93%的产率得到potassium N,N-diallyl(trifluoroboratomethyl)amine
  参考文献：
  名称：

  Aminomethylations via Cross-Coupling of Potassium Organotrifluoroborates with Aryl Bromides

  摘要：

  [GRAPHICS]The Suzuki-Miyaura cross-coupling reaction of N,N-dialkylaminomethyltrifluoroborates with aryl halides allows the construction of an aminomethyl aryl linkage through a disconnection based on dissonant reactivity patterns. A variety of these aminomethyltrifluoroborate substrates were prepared in good to excellent yields and then shown to cross-couple with equal facility to both electron-rich and electron-poor aryl halides as well as to a variety of heteroaromatic bromides.

  DOI：

  10.1021/ol070543e

文献信息

• Aminomethylations via Cross-Coupling of Potassium Organotrifluoroborates with Aryl Bromides
  作者：Gary A. Molander、Deidre L. Sandrock

  DOI：10.1021/ol070543e

  日期：2007.4.1

  [GRAPHICS]The Suzuki-Miyaura cross-coupling reaction of N,N-dialkylaminomethyltrifluoroborates with aryl halides allows the construction of an aminomethyl aryl linkage through a disconnection based on dissonant reactivity patterns. A variety of these aminomethyltrifluoroborate substrates were prepared in good to excellent yields and then shown to cross-couple with equal facility to both electron-rich and electron-poor aryl halides as well as to a variety of heteroaromatic bromides.