4-((3,5-difluoro-4'-propyl-[1,1'-biphenyl]-4-yl)difluoromethoxy)-2,6-difluorophenol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-((3,5-difluoro-4'-propyl-[1,1'-biphenyl]-4-yl)difluoromethoxy)-2,6-difluorophenol
• 英文别名: 4-[[2,6-Difluoro-4-(4-propylphenyl)phenyl]-difluoromethoxy]-2,6-difluorophenol；4-[[2,6-difluoro-4-(4-propylphenyl)phenyl]-difluoromethoxy]-2,6-difluorophenol
• 化学式: C₂₂H₁₆F₆O₂
• 分子量: 426.358
• InChiKey: KPNJUEVBWKWBPP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  4-((3,5-difluoro-4'-propyl-[1,1'-biphenyl]-4-yl)difluoromethoxy)-2,6-difluorophenol 、 (E)-1-氯-3,3,3-三氟丙烯 在 sodium hydride 作用下， 以 N-甲基吡咯烷酮 、 mineral oil 为溶剂， 反应 24.5h， 以48%的产率得到(E)-4-((3,5-difluoro-4-((3,3,3-trifluoro-1-propene-lyl)oxy)phenoxy)difluoromethyl)-3,5-difluoro-4'-propyl-1,1'-biphenyl
  参考文献：
  名称：

  JP6299011

  摘要：

  公开号：

文献信息

• ポリフルオロ−２−ブテノキシ基を有する液晶性化合物、液晶組成物、および液晶表示素子
  申请人：ＪＮＣ株式会社

  公开号：JP2018016589A

  公开（公告）日：2018-02-01

  【課題】類似の化合物と比較して、大きな誘電率異方性や、優れた加熱信頼性を有する液晶性化合物、この化合物を含有する液晶組成物、この組成物を含む液晶表示素子を提供する。【解決手段】式（１）で表される化合物。式（１）において、例えば、Ｒ１は炭素数１〜１５のアルキルであり；環Ａ１は、１，４−シクロへキシレン、１，４−シクロヘキセニレン、１，４−フェニレン、少なくとも１つの水素がハロゲンで置き換えられた１，４−フェニレン、または１，３−ジオキサン−２，５−ジイルであり；Ｚ１は単結合または−ＣＦ２Ｏ−であり；Ｌ１およびＬ２は、水素またはハロゲンであり；Ｙ１およびＹ２は、水素またはハロゲンであり；ａは１〜４の整数である。【選択図】なし

  【问题】提供一种含有化合物的液晶组合物，该化合物具有与类似化合物相比较大的介电畸变率和出色的加热可靠性，并提供包含该组合物的液晶显示元件。 【解决方案】由式（1）表示的化合物。在式（1）中，例如，R1是1-15碳的烷基；环A1是1,4-环己烯基，1,4-环己烯基，1,4-苯基，至少有一个氢被卤素取代的1,4-苯基，或1,3-二氧杂环戊烷-2,5-二基；Z1是单键或-CF2O-；L1和L2是氢或卤素；Y1和Y2是氢或卤素；a是1-4的整数。【选项图】无
• Liquid crystal compound having polyfluoro-2-butenoxy group, liquid crystal composition and liquid crystal display device
  申请人：JNC CORPORATION

  公开号：US10358602B2

  公开（公告）日：2019-07-23

  Provided are a liquid crystal compound having larger dielectric anisotropy and superb heating reliability in comparison with a similar compound, a liquid crystal composition containing the compound and a liquid crystal display device including the composition. A compound is represented by formula (1). In formula (1), for example, R1 is alkyl having 1 to 15 carbons, ring A1 is 1,4-cyclohexylene, 1,4-cyclohexenylene, 1,4-phenylene, 1,4-phenylene in which at least one hydrogen is replaced by halogen or tetrahydropyran-2,5-diyl; Z1 is a single bond or —CF2O—; L1 and L2 are hydrogen or halogen; Y1 and Y2 are hydrogen or halogen; and a is an integer from 1 to 4.

  本发明提供了一种与同类化合物相比具有较大介电各向异性和极佳加热可靠性的液晶化合物、一种含有该化合物的液晶组合物以及一种包括该组合物的液晶显示设备。一种化合物用式（1）表示。 例如，在式 (1) 中，R1 是具有 1 至 15 个碳原子的烷基，环 A1 是 1,4-环己烯、1,4-环己烯、1,4-亚苯基、其中至少一个氢被卤素或四氢吡喃-2,5-二基取代的 1,4-亚苯基；Z1 是单键或-CF2O-；L1 和 L2 是氢或卤素；Y1 和 Y2 是氢或卤素；a 是 1 至 4 的整数。
• LIQUID CRYSTAL COMPOUND HAVING 1,1,3,3-TETRAFLUOROALLYLOXY GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT
  申请人：JNC Corporation

  公开号：EP3135659B1

  公开（公告）日：2018-12-19
• COMPOUND HAVING 3,3,3-TRIFLUORO-1-PROPENYLOXY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：JNC PETROCHEMICAL CORPORATION

  公开号：US20140203209A1

  公开（公告）日：2014-07-24

  An object is to provide a liquid crystal compound satisfying at least one of physical properties such as a high stability to heat, light and so forth, a high clearing point, a low minimum temperature of a liquid crystal phase, a small viscosity, a suitable optical anisotropy, a large dielectric anisotropy, a suitable elastic constant and an excellent compatibility with other liquid crystal compounds, a liquid crystal composition containing the compound, and a liquid crystal display device including the composition. A solution is the compound represented by formula (1): wherein, in formula (1), for example, R 1 is alkyl having 1 to 10 carbons; ring A 1 and ring A 2 are independently 1,4-cyclohexylene or 1,4-phenylene; Z 1 and Z 2 are independently a single bond or —CF 2 O—; L 1 and L 2 are halogen; and a is 1 or 2.
• LIQUID CRYSTAL COMPOUND HAVING 1,1,3,3-TETRAFLUOROALLYLOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：JNC CORPORATION

  公开号：US20160362605A1

  公开（公告）日：2016-12-15

  To show a liquid crystal compound satisfying at least one of physical properties such as a high stability to heat, light or the like, a high clearing point, a low minimum temperature of a liquid crystal phase, a small viscosity, a suitable optical anisotropy, a large dielectric anisotropy, a suitable elastic constant and an excellent compatibility with other liquid crystal compounds, a liquid crystal composition containing the compound and a liquid crystal display device including the composition. A compound represented by formula (1): wherein, in formula (1), for example, R 1 is alkyl having 1 to 15 carbons; ring A 1 and ring A 2 are 1,4-cyclohexylene, 1,4-cyclohexenylene, 1,4-phenylene, 1,4-phenylene in which at least one piece of hydrogen is replaced by halogen, tetrahydropyran-2,5-diyl or 1,3-dioxane-2,5-diyl; Z 1 and Z 2 are a single bond or —CF 2 O—; L 1 , L 2 and L 3 are halogen or hydrogen; and a is 0 to 3.