1-(4-bromobenzyl)-4-phenylpiperazine | 368879-18-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 1-(4-bromobenzyl)-4-phenylpiperazine
• 英文别名: 1-[(4-Bromophenyl)methyl]-4-phenylpiperazine
• CAS: 368879-18-9
• 化学式: C₁₇H₁₉BrN₂
• 分子量: 331.255
• InChiKey: WRAPDKOLIXFVMT-UHFFFAOYSA-N

物化性质

• 沸点：
  424.6±40.0 °C(Predicted)
• 密度：
  1.339±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-氨基苯并噻唑 、 1-(4-bromobenzyl)-4-phenylpiperazine 在 亚硝酸 、 溶剂黄146 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以92%的产率得到1-(4-bromobenzyl)-4-(4-(benzothiazolylazo)phenyl)piperazine
  参考文献：
  名称：

  Novel push–pull heterocyclic azo disperse dyes containing piperazine moiety: Synthesis, spectral properties, antioxidant activity and dyeing performance on polyester fibers

  摘要：

  Six novel push-pull azo disperse dyes were synthesized via classical azo coupling reaction using 2-amino-thiazolyl derivatives as the diazo components and 1-(4-bromobenzyl)-4-phenylpiperazine as a key coupling intermediate. The structures of the dyes and synthesized intermediate were confirmed by FT-IR, H-1 NMR, C-13 NMR and UV-vis analyses. The solvatochromic behavior of the dyes was studied in a set of 10 solvents of different polarity and considerable results were obtained. The prepared heterocyclic azo dyes were applied for dyeing polyester fibers and their dyeing properties were studied. The fastness properties of the dyed fabrics such as wash, light and rubbing fastness degrees were measured by standard methods. Investigation of antioxidant activity of compounds was carried out by ferric reducing antioxidant power (FRAP) method. The synthesized dyes exhibited significant antioxidant activities. (C) 2015 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2015.06.024
• 作为产物：
  描述：

  N-苯基哌嗪 、 对溴溴苄 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以96%的产率得到1-(4-bromobenzyl)-4-phenylpiperazine
  参考文献：
  名称：

  Novel push–pull heterocyclic azo disperse dyes containing piperazine moiety: Synthesis, spectral properties, antioxidant activity and dyeing performance on polyester fibers

  摘要：

  Six novel push-pull azo disperse dyes were synthesized via classical azo coupling reaction using 2-amino-thiazolyl derivatives as the diazo components and 1-(4-bromobenzyl)-4-phenylpiperazine as a key coupling intermediate. The structures of the dyes and synthesized intermediate were confirmed by FT-IR, H-1 NMR, C-13 NMR and UV-vis analyses. The solvatochromic behavior of the dyes was studied in a set of 10 solvents of different polarity and considerable results were obtained. The prepared heterocyclic azo dyes were applied for dyeing polyester fibers and their dyeing properties were studied. The fastness properties of the dyed fabrics such as wash, light and rubbing fastness degrees were measured by standard methods. Investigation of antioxidant activity of compounds was carried out by ferric reducing antioxidant power (FRAP) method. The synthesized dyes exhibited significant antioxidant activities. (C) 2015 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2015.06.024

文献信息

• Novel push–pull heterocyclic azo disperse dyes containing piperazine moiety: Synthesis, spectral properties, antioxidant activity and dyeing performance on polyester fibers
  作者：Asadollah Mohammadi、Behzad Khalili、Marzieh Tahavor

  DOI：10.1016/j.saa.2015.06.024

  日期：2015.11

  Six novel push-pull azo disperse dyes were synthesized via classical azo coupling reaction using 2-amino-thiazolyl derivatives as the diazo components and 1-(4-bromobenzyl)-4-phenylpiperazine as a key coupling intermediate. The structures of the dyes and synthesized intermediate were confirmed by FT-IR, H-1 NMR, C-13 NMR and UV-vis analyses. The solvatochromic behavior of the dyes was studied in a set of 10 solvents of different polarity and considerable results were obtained. The prepared heterocyclic azo dyes were applied for dyeing polyester fibers and their dyeing properties were studied. The fastness properties of the dyed fabrics such as wash, light and rubbing fastness degrees were measured by standard methods. Investigation of antioxidant activity of compounds was carried out by ferric reducing antioxidant power (FRAP) method. The synthesized dyes exhibited significant antioxidant activities. (C) 2015 Elsevier B.V. All rights reserved.