2,2-dichloro-N-[(R)-1-phenylethyl]acetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2-dichloro-N-[(R)-1-phenylethyl]acetamide
• 英文别名: (r)-2,2-dichloro-N-(1-phenylethyl)acetamide；2,2-dichloro-N-[(1R)-1-phenylethyl]acetamide
• 化学式: C₁₀H₁₁Cl₂NO
• 分子量: 232.109
• InChiKey: OKVKOBMHKRIIOW-SSDOTTSWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2,2-dichloro-N-[(R)-1-phenylethyl]acetamide 、 足球烯 在 sodium hydride 作用下， 以 邻二氯苯 为溶剂， 反应 0.17h， 以40%的产率得到3'-chloro-N-[(R)-1-phenylethyl]-3'H-cyclopropa-[1,9](C₆₀-I_h)[5,6]fullerene-3'-carboxamide
  参考文献：
  名称：

  Synthesis of a conjugate of (R)-2,2-dichloro- N-(1-phenylethyl)acetamide with fullerene C60

  摘要：

  The Bingel-Hirsch reaction of (R)-2.2-dichloro-N-(1-phenylethy)acetamide with fullerene C-60 gave the corresponding methanofullerene, and its electrochemical and physical properties were studied. The electron-acceptor characteristics of the new compound were found to be similar to those of the known methanofullerene [60]PCBM.

  DOI：

  10.1134/s1070428017100153
• 作为产物：
  描述：

  二氯乙酰氯 、 R(+)-alpha-甲基苄胺 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 5.0h， 以92%的产率得到2,2-dichloro-N-[(R)-1-phenylethyl]acetamide
  参考文献：
  名称：

  Synthesis of a conjugate of (R)-2,2-dichloro- N-(1-phenylethyl)acetamide with fullerene C60

  摘要：

  The Bingel-Hirsch reaction of (R)-2.2-dichloro-N-(1-phenylethy)acetamide with fullerene C-60 gave the corresponding methanofullerene, and its electrochemical and physical properties were studied. The electron-acceptor characteristics of the new compound were found to be similar to those of the known methanofullerene [60]PCBM.

  DOI：

  10.1134/s1070428017100153

文献信息

• Synthesis of a conjugate of (R)-2,2-dichloro- N-(1-phenylethyl)acetamide with fullerene C60
  作者：S. A. Torosyan、Yu. N. Biglova、Z. F. Nuriakhmetova、M. S. Miftakhov

  DOI：10.1134/s1070428017100153

  日期：2017.10

  The Bingel-Hirsch reaction of (R)-2.2-dichloro-N-(1-phenylethy)acetamide with fullerene C-60 gave the corresponding methanofullerene, and its electrochemical and physical properties were studied. The electron-acceptor characteristics of the new compound were found to be similar to those of the known methanofullerene [60]PCBM.