ethyl 2-[4-(quinolin-3-yloxy)phenoxy]propionate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: ethyl 2-[4-(quinolin-3-yloxy)phenoxy]propionate
• 英文别名: Ethyl 2-[4-(3-quinolinyloxy)phenoxy]propionate；ethyl 2-(4-quinolin-3-yloxyphenoxy)propanoate
• 化学式: C₂₀H₁₉NO₄
• 分子量: 337.375
• InChiKey: FFIQJNUVCUFBKT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  57.6
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  3-(4-hydroxyphenoxy)quinoline 、 2-溴丙酸乙酯 在 potassium carbonate 作用下， 以 N-甲基乙酰胺 为溶剂， 生成 ethyl 2-[4-(quinolin-3-yloxy)phenoxy]propionate
  参考文献：
  名称：

  Ethyl 2[4-(7-chloroquinolin-3-yloxy)phenoxy]propionate, the N-oxide, and

  摘要：

  这项发明涉及公式I的新化合物。这些化合物是除草剂，而且在进一步的实施中，该发明提供了含有公式I化合物作为活性成分的除草剂组合物，以及通过向植物或植物生长介质施加公式I化合物的有效量来严重损害或杀死不受欢迎的植物的方法。

  公开号：

  US04444584A1

文献信息

• Herbicidal alkane carboxylic acid derivatives
  申请人：ICI Australia Limited

  公开号：US04738710A1

  公开（公告）日：1988-04-19

  The invention concerns novel compounds of the formula I ##STR1## wherein: A, B, D, E, J.sup.1, J.sup.2, U and V are chosen from hydrogen, halogen, nitro, cyano, thiocyano, amino, substituted amino, alkyl, substituted alkyl, alkenyl, cycloalkyl, alkoxy, substituted alkoxy, alkylthio, alkylsulfinyl, substituted alkylsulfinyl, alkylsulfonyl, substituted alkylsulfonyl, sulfamoyl, substituted sulfamoyl, sulfo, carboxy, alkoxycarbonyl, carbamoyl, substituted carbamoyl and optionally substituted phenyl, phenoxy and phenylthio; R.sup.1 is chosen from hydrogen, alkyl, substituted alkyl, alkenyl, alkanoyl and alkoxycarbonyl; R.sup.2 is chosen from hydrogen, alkyl, substituted alkyl and alkenyl; or R.sup.1 and R.sup.2 together form an alkylidene group; W is chosen from cyano, thiocarbamoyl, the group --CH.sub.2 Z wherein Z is chosen from halogen, hydroxy, mercapto, alkoxy, haloalkoxy, alkylthio and optionally substituted amino, and the group ##STR2## which may be a carboxylic acid group or a derivative thereof such as an acid salt, acid ester, acid amide, acid sulfonamide or acid oxime ester; X is chosen from oxygen and sulfur; Y is chosen from oxygen sulfur and optionally substituted imino; .phi. is chosen from oxygen and RAn wherein R is alkyl or benzyl and An is an anion; k is 0 or 1; and n is 0, 1 or 2. The compounds are herbicides and in further embodiments the invention provides herbicidal compositions containing as active ingredient a compound of formula I and a process for severely damaging or killing unwanted plants by applying to the plants or to the growth medium of the plants an effective amount of a compound of formula I.

  本发明涉及一种新型化合物，其化学式为I ##STR3## 其中：A、B、D、E、J.sup.1、J.sup.2、U和V选择自氢、卤素、硝基、氰基、硫氰基、氨基、取代氨基、烷基、取代烷基、烯基、环烷基、烷氧基、取代烷氧基、烷硫基、烷基磺酰基、取代烷基磺酰基、烷基磺酰基、取代烷基磺酰基、磺酰胺基、取代磺酰胺基、磺酸基、取代磺酸基、磺酰氨基、取代磺酰氨基、磺酰基、取代磺酰基、羧基、烷氧羰基、氨基甲酰基、取代氨基甲酰基和可选取代的苯基、苯氧基和苯基硫醚；R.sup.1选择自氢、烷基、取代烷基、烯基、烷酰基和烷氧羰基；R.sup.2选择自氢、烷基、取代烷基和烯基；或R.sup.1和R.sup.2一起形成一个烷基亚甲基基团；W选择自氰基、硫代氨基、--CH.sub.2 Z基团，其中Z选择自卤素、羟基、巯基、烷氧基、卤代烷氧基、烷硫基和可选取代的氨基，以及##STR4##它可以是羧酸基或其衍生物，例如酸盐、酸酯、酰胺、磺酰胺或氧化酮酯；X选择自氧和硫；Y选择自氧、硫和可选取代的亚胺基；.phi.选择自氧和RAn，其中R为烷基或苄基，An为阴离子；k为0或1；n为0、1或2。这些化合物是除草剂，在进一步实施方案中，本发明提供了包含化合物I的除草剂组合物，并通过向植物或植物生长介质施加化合物I的有效量来严重损伤或杀死不需要的植物的方法。
• Quinolinyloxy(amino)phenoxyalkane carboxylic acid derivatives, process for their synthesis, herbicidal compositions containing them and their use as herbicides
  申请人：ICI AUSTRALIA LIMITED

  公开号：EP0029319A2

  公开（公告）日：1981-05-27

  The invention concerns novel compounds of the formula I The compounds are herbicides and in further embodiments the invention provides herbicidal compositions containing as active ingredient a compound of formula I and a process for severely damaging or killing unwanted plants by applying to the plants or to the growth medium of the plants an effective amount of a compound of formula I.

  本发明涉及式 I 的新型化合物。 这些化合物是除草剂，在进一步的实施方案中，本发明提供了含有作为活性成分的式 I 化合物的除草组合物，以及通过向植物或植物的生长介质施用有效量的式 I 化合物来严重损害或杀死不需要的植物的工艺。
• Quinolin-3-yloxy(amino)phenoxyalkane carboxylic acid derivatives, process for their synthesis, herbicidal compositions containing them, and their use as herbicides
  申请人：ICI AUSTRALIA LIMITED

  公开号：EP0063866A1

  公开（公告）日：1982-11-03

  The invention concerns novel compounds of the formula I wherein: A, B, D, E, J1, J2, U and V are chosen from hydrogen, halogen, nitro, cyano, thiocyano, amino, substituted amino, alkyl, substituted alkyl, alkenyl, cycloalkyl, alkoxy, substituted alkoxy, alkylthio, alkylsulfinyl, substituted alkylsulfinyl, alkylsulfonyl, substituted alkylsulfonyl. sulfamoyl. substituted sulfamoyl, sulfo, carboxy, alkoxycarbonyl, carbamoyl, substituted carbamoyl and optionally substituted phenyl, phenoxy and phenylthio; R1 is chosen from hydrogen, alkyl, substituted alkyl, alkenyl, alkanoyl and alkoxycarbonyl; R2 is chosen from hydrogen, alkyl, substituted alkyl and alkenyl; or R1 and R2 together form an alkylidene group; W is chosen from cyano, thiocarbamoyl, the group -CHzZ wherein Z is chosen from halogen, hydroxy, mercapto, alkoxy, haloalkoxy, alkylthio and optionally substituted amino, and the group which may be a carboxylic acid group or a derivative thereof such as an acid salt, acid ester, acid amide, acid sulfonamide or acid oxime ester; X is chosen from oxygen and sulfur; Y is chosen from oxygen sulfur and optionally substituted imino; Ø is chosen from oxygen and RAn wherein R is alkyl or benzyl and An is an anion; k is 0or 1; and n is 0, 1 or 2. The compounds are herbicides and in further embodiments the invention provides herbicidal compositions containing as active ingredient a compound of formula and a process for severely damaging or killing unwanted plants by applying to the plants or to the growth medium of the plants an effective amount of a compound of formula I.

  本发明涉及式 I 的新型化合物 其中 A、B、D、E、J1、J2、U 和 V 选自氢、卤素、硝基、氰基、硫氰基、氨基、取代氨基、烷基、取代烷基、烯基、环烷基、烷氧基、取代烷氧基、烷硫基、烷基亚磺酰基、取代烷基亚磺酰基、烷基磺酰基、取代烷基磺酰基、氨基磺酰基、取代氨基磺酰基、磺酰基、羧基、烷氧基羰基、氨基甲酰基、取代氨基甲酰基和任选取代的苯基、苯氧基羰基、氨基羰基和任选取代的苯基。R1选自氢、烷基、取代的烷基、烯基、烷酰基和烷氧羰基；R2选自氢、烷基、取代的烷基和烯基；或 R1 和 R2 共同形成亚烷基； W 选自氰基、硫代氨基甲酰基、基团 -CHzZ，其中 Z 选自卤素、羟基、巯基、烷氧基、卤代烷氧基、烷硫基和任选取代的氨基，以及基团 可为羧酸基团或其衍生物，如酸盐、酸酯、酸酰胺、酸磺酰胺或酸肟酯； X 选自氧和硫； Y 选自氧硫和任选取代的亚氨基； Ø 选自氧和 RAn，其中 R 是烷基或苄基，An 是阴离子； k 为 0 或 1；以及 n 为 0、1 或 2。 本发明的化合物是除草剂，在进一步的实施方案中，本发明提供了含有作为活性成分的式化合物的除草组合物，以及通过向植物或植物的生长介质施用有效量的式I化合物来严重损害或杀死不需要的植物的工艺。
• SERBAN, A.;WATSON, K. G.
  作者：SERBAN, A.、WATSON, K. G.

  DOI：——

  日期：——
• US4444584A
  申请人：——

  公开号：US4444584A

  公开（公告）日：1984-04-24