4'-methyl-4-ethoxy-1,1'-biphenyl

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4'-methyl-4-ethoxy-1,1'-biphenyl
• 英文别名: 4-ethoxy-4'-methyl-1,1'-biphenyl；1-ethoxy-4-(4-methylphenyl)benzene
• 化学式: C₁₅H₁₆O
• 分子量: 212.291
• InChiKey: XRAVMHGIQUVWMN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  4-碘苯乙醚 、 4-甲苯硼酸 在 potassium carbonate 作用下， 以 乙醇 、 水 为溶剂， 反应 10.0h， 以99%的产率得到4'-methyl-4-ethoxy-1,1'-biphenyl
  参考文献：
  名称：

  Trace amount Cu^II (ppm) and mixture design of Cu^II/Pd^II catalyzed Suzuki cross-coupling reactions based on the cooperative interaction of metal with a conjugated pyridylspirobifluorene

  摘要：

  PEI-(Cu/psf)_n的多层结构可能能够逐渐释放高活性催化基团，促进C-C偶联反应，铜负载量极低，为1.4 × 10⁻⁵ mol%。

  DOI：

  10.1039/c5ta00222b

文献信息

• MELANIN PRODUCTION INHIBITOR
  申请人：Yokoyama Kouji

  公开号：US20110243865A1

  公开（公告）日：2011-10-06

  Disclosed is a melanin production inhibitor which has an excellent inhibitory activity on the production of melanin and is highly safe. The melanin production inhibitor comprises a compound represented by general formula (1) (excluding clotrimazole), and/or a pharmacologically acceptable salt thereof. In the formula, A1, A2 and A3 are independently selected from a hydrogen atom, an aryl group which may have a substituent, and an aromatic heterocyclic group which may have a substituent, wherein at least one of A1, A2 and A3 is selected from the aryl group and the aromatic heterocyclic group, the total number of carbon atoms contained in A1, A2 and A3 is 6 to 50 and, when at least two of A1, A2 and A3 represent the aryl groups or the aromatic heterocyclic groups, the adjacent two aryl or aromatic heterocyclic groups may be bound to each other via an alkyl chain or an alkenyl chain to form a ring; m represents an integer of 0 to 2; X represents a hetero atom, a hydrogen atom, or a carbon atom; R1 and R2 are independently selected from a hydrogen atom and an oxo group, wherein when one of R1 and R2 is an oxo group, the other is not present; and R3 is selected from a hydrogen atom, and a C 1-8 hydrocarbon group in which one or some of hydrogen atoms or carbon atoms may be substituted by a hetero atom or hetero atoms, wherein the number of R3's present in the compound corresponds to the number of X's and, when two or more R3's are present, the R3's are independently present and the adjacent two R3's may be bound to each other to form, together with X, a ring, and the terminal of R3 may be bound to a carbon atom to which A1, A2 and A3 are bound, thereby forming a ring.

  披露了一种黑色素生产抑制剂，它对黑色素的生产具有出色的抑制活性且高度安全。该黑色素生产抑制剂包括由通用公式（1）表示的化合物（不包括克霉唑）和/或其药理上可接受的盐。在公式中，A1、A2和A3独立地选自氢原子、可能带有取代基的芳基团和可能带有取代基的芳香杂环团，其中至少A1、A2和A3之一选自芳基团和芳香杂环团，A1、A2和A3中包含的碳原子总数为6至50，并且当至少两个A1、A2和A3表示芳基团或芳香杂环团时，相邻的两个芳基或芳香杂环团可以通过烷基链或烯基链相互连接形成环；m代表0至2的整数；X代表异原子、氢原子或碳原子；R1和R2独立地选自氢原子和氧代基，其中当R1和R2之一是氧代基时，另一个不出现；R3选自氢原子和C 1-8 碳氢化合物组，其中一些或所有的氢原子或碳原子可能被异原子或异原子取代，其中化合物中存在的R3的数量对应于X的数量，并且当存在两个或更多R3时，R3独立地存在，并且相邻的两个R3可以相互连接以与X一起形成环，并且R3的末端可以与A1、A2和A3连接的碳原子结合，从而形成环。
• N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY
  申请人：Jain Rakesh Kumar

  公开号：US20100022605A1

  公开（公告）日：2010-01-28

  Described herein are N-hydroxyamlde antibacterial compounds, methods for making the compounds, pharmaceutical compositions containing the compounds and methods of treating bacterial infections utilizing the compounds and pharmaceutical compositions compound of Formula (I): or a salt, solvate ti hydrate thereof, wherein A is (a) each indicates a point of attachment.

  本文描述了N-羟基酰胺抗菌化合物，制备这些化合物的方法，含有这些化合物的制药组合物，以及利用这些化合物和制药组合物治疗细菌感染的方法。化合物的化学式如下：或其盐、溶剂合物或水合物，其中A是（a）表示连接点。
• A highly active multi-usable palladium pyridylfluorene film-based catalyst for C-C cross-coupling reactions
  作者：Xiuhua Zhao、Yayun Zhao、Jie Zhang、Xing Li

  DOI：10.1002/aoc.3391

  日期：2015.12

  bilayers, more particulate aggregates are distributed on the surface. When released from the substrate, the Pd(II) complex nanostructure shows high catalytic activity for Suzuki–Miyaura and Mizoroki–Heck cross‐coupling reactions. The catalyst loading is as low as 9.1 × 10−3 mol% Pd, as measured using ICP‐AES, and high turnover numbers of up to 1.08 × 104 are obtained. Copyright © 2015 John Wiley & Sons

  2,7-双（4-吡啶基）芴的两个末端吡啶基氮原子（1）与Pd（II）离子配位，从而使用逐层（LbL）方法得到自组装的多层薄膜。通过将预先涂有聚乙烯亚胺层的基材交替浸入PdCl 2的水溶液和1的乙醇溶液中来制备薄膜。使用紫外可见吸收光谱，原子力显微镜（AFM），X射线光电子能谱，扫描电子显微镜（SEM）和电感耦合等离子体原子发射光谱（ICP-AES）对得到的膜进行表征。紫外可见光谱和SEM图像显示，薄膜以接近理想的LbL方式几乎均匀地生长。AFM图像显示Pd（II）配合物的纳米结构聚集体形成在表面上。随着Pd（II）/ 1双层数量的增加，更多的颗粒聚集体分布在表面上。当从底物中释放出来时，Pd（II）复杂的纳米结构显示出对Suzuki–Miyaura和Mizoroki–Heck交叉偶联反应的高催化活性。催化剂负载低至9.1×10 -3使用ICP‐AES测得的Pd为mol％，可获得高达1.08×10
• 一种芴酮吡啶镍纳米簇及其制备方法
  申请人：宁波大学

  公开号：CN105906670B

  公开（公告）日：2018-09-28

  本发明公开了一种芴酮吡啶镍纳米簇及其制备方法，本发明中将芴酮吡啶有机配体溶液滴加至金属盐溶液中，反应结束后超声分散，离心分离，洗涤，真空干燥制得相应的配体‑金属纳米簇，制备过程简单，成本低；通过改变溶剂，反应物的浓度、反应时间和温度，实现对纳米簇形貌的有效调控。本发明制备的芴酮吡啶镍纳米簇能够高效催化C‑C交叉偶联反应，产率可达70％以上。因此该芴酮吡啶镍纳米簇在催化领域具有广阔的应用。
• Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative
  申请人：Murata Hiroko

  公开号：US20070149784A1

  公开（公告）日：2007-06-28

  An oxadiazole derivative represented by the following general formula (G1) is synthesized and applied to the light emitting element, wherein A m is a substituent represented by a general formula (Am1), (Am2), or (Am3); each of α, β 1 , and β 2 represents an arylene group having 6 to 25 carbon atoms; each of A r 1 to A r 6 represents an aryl group having 6 to 25 carbon atoms; each of R 1 to R 3 represents hydrogen, an alkyl group having 1 to 4 carbon atoms, or an aryl group having 6 to 25 carbon atoms; and R 4 represents an alkyl group having 1 to 4 carbon atoms or an aryl group having 6 to 25 carbon atoms.

  由以下一般式（G1）表示的一种噁二唑衍生物被合成并应用于发光元件，其中Am是由一般式（Am1）、（Am2）或（Am3）表示的取代基；α、β1和β2分别表示具有6至25个碳原子的芳基基团；Ar1至Ar6分别表示具有6至25个碳原子的芳基基团；R1至R3分别表示氢、具有1至4个碳原子的烷基基团或具有6至25个碳原子的芳基基团；R4表示具有1至4个碳原子的烷基基团或具有6至25个碳原子的芳基基团。