单水合亚硫酸铵 | 7783-11-1

• 物质功能分类: 无机化工 - 无机盐 - 金属硫化物及硫酸盐
• 分子结构分类: 无机化合物 - 均质非金属化合物 - 非金属氧阴离子化合物
• 中文名称: 单水合亚硫酸铵
• 中文别名: 亚硫酸铵(一水)；亚硫酸铵；亚硫酸铵水合物
• 英文名称: Diammonium sulfite monohydrate
• 英文别名: diazanium;sulfite;hydrate
• CAS: 7783-11-1
• 化学式: H10N2O4S
• 分子量: 134.16
• InChiKey: ASPXBYAQZVXSNS-UHFFFAOYSA-N

物化性质

• 熔点：
  60-70°C
• 密度：
  1.41 g/mL at 25 °C(lit.)
• 溶解度：
  不溶于乙醇、丙酮
• 稳定性/保质期：
  1. 溶于水（0℃时32.4g/100ml水；100℃时60.4g/100ml水），其水溶液呈碱性。微溶于醇，不溶于丙酮和二硫化碳。在空气中易氧化，在60～70℃时分解。易溶于水，加热时会渐渐失水并被氧化为(NH4)2SO4。

计算性质

• 辛醇/水分配系数(LogP)：
  -1.08
• 重原子数：
  7
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  85.4
• 氢给体数：
  3
• 氢受体数：
  5

安全信息

• TSCA：
  Yes
• 危险品标志：
  Xi
• 安全说明：
  S26,S36
• 危险类别码：
  R31
• WGK Germany：
  3
• 危险品运输编号：
  UN3077 9/PG 3

SDS

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SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifiers
Product name : Ammonium sulfite monohydrate
REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not
require a registration or the registration is envisaged for a later
registration deadline.
CAS-No. : 7783-11-1
Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances

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SECTION 2: Hazards identification
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Skin irritation (Category 2), H315
Eye irritation (Category 2), H319
Specific target organ toxicity - single exposure (Category 3), H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Xi Irritant R31, R36/37/38
For the full text of the R-phrases mentioned in this Section, see Section 16.
Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram
Signal word Warning
Hazard statement(s)
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
Precautionary statement(s)
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
Supplemental Hazard information (EU)
EUH031 Contact with acids liberates toxic gas.
Safety data sheet available on request.
Other hazards - none

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SECTION 3: Composition/information on ingredients
Substances
Formula : H8N2O3S · H2O
Molecular Weight : 134,16 g/mol
CAS-No. : 7783-11-1
EC-No. : 233-484-9
Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Ammonium sulphite
Skin Irrit. 2; Eye Irrit. 2; STOT -
SE 3; H315, H319, H335,
EUH031
Hazardous ingredients according to Directive 1999/45/EC
Component Classification Concentration
Ammonium sulphite
Xi, R31 - R36/37/38 -
For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

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SECTION 4: First aid measures
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
Indication of any immediate medical attention and special treatment needed
no data available

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SECTION 5: Firefighting measures
Extinguishing media
Suitable extinguishing media
Dry powder
Special hazards arising from the substance or mixture
nitrogen oxides (NOx), Sulphur oxides
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
no data available

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SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure
adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Do not flush with water. Keep
in suitable, closed containers for disposal.
Reference to other sections
For disposal see section 13.

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SECTION 7: Handling and storage
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Never allow product to get in contact with water during storage. Do not store near acids.
Handle and store under inert gas. Air sensitive.
Specific end use(s)
A part from the uses mentioned in section 1.2 no other specific uses are stipulated

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SECTION 8: Exposure controls/personal protection
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested
and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Z677272, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone [phone], test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374,
contact the supplier of the CE approved gloves. This recommendation is advisory only and must
be evaluated by an industrial hygienist and safety officer familiar with the specific situation of
anticipated use by our customers. It should not be construed as offering an approval for any
specific use scenario.
Body Protection
impervious clothing, The type of protective equipment must be selected according to the
concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle
respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering
controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use
respirators and components tested and approved under appropriate government standards such
as NIOSH (US) or CEN (EU).
Control of environmental exposure
Do not let product enter drains.

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SECTION 9: Physical and chemical properties
Information on basic physical and chemical properties
a) Appearance Form: solid
b) Odour no data available
c) Odour Threshold no data available
d) pH no data available
e) Melting point/freezing no data available
point
f) Initial boiling point and no data available
boiling range
g) Flash point not applicable
h) Evapouration rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower no data available
flammability or
explosive limits
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density 1,41 g/cm3 at 25 °C
n) Water solubility no data available
o) Partition coefficient: n- no data available
octanol/water
p) Auto-ignition no data available
temperature
q) Decomposition no data available
temperature
r) Viscosity no data available
s) Explosive properties no data available
t) Oxidizing properties no data available
Other safety information
no data available

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SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
no data available
Conditions to avoid
Air
Incompatible materials
Strong oxidizing agents, Do not store near acids.
Hazardous decomposition products
Other decomposition products - no data available
In the event of fire: see section 5

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SECTION 11: Toxicological information
Information on toxicological effects
Acute toxicity
no data available
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitisation
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation.
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Additional Information
RTECS: Not available
Gastrointestinal tract, Diarrhoea, Central nervous system depression, To the best of our knowledge, the
chemical, physical, and toxicological properties have not been thoroughly investigated.

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SECTION 12: Ecological information
Toxicity
no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
Other adverse effects
no data available

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SECTION 13: Disposal considerations
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.

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SECTION 14: Transport information
UN number
ADR/RID: - IMDG: - IATA: -
UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
Packaging group
ADR/RID: - IMDG: - IATA: -
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
no data available

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SECTION 15 - REGULATORY INFORMATION
N/A

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SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

简介

单水合亚硫酸铵是一种无色单斜晶体，熔点为60～70℃（分解），沸点150℃（升华）。其相对密度为1.4125，折光率为1.515。该物质溶于水，微溶于乙醇，难溶于丙酮。

应用

单水合亚硫酸铵主要用于造纸工业，也可作为生产快速显影液硫代硫酸铵的原料，并用于有机合成中的还原剂和磺化剂，还可用作日用化学品卷发液的生产原料。

制备

单水合亚硫酸铵可由氨水与二氧化硫作用制得。具体方法包括将二氧化硫通入氨水中或（NH4）2CO3溶液中，在0℃左右进行反应。另一种方法是用水或母液吸收制硫酸尾气中的二氧化硫或焚硫烟气中的二氧化硫，再加入氨水或碳酸氢铵中和反应。

氨水法

将氨水配制成一定比重和碱度的溶液，循环吸收制硫酸尾气或焚硫烟气中的二氧化硫。当吸收液相对密度达到1.30～1.32时送入中和器，再加入氨水中和反应至终点，经离心分离、干燥，可制得亚硫酸铵成品。

碳酸氢铵法

用母液或氨水吸收溶液以制备硫酸尾气中的二氧化硫。当吸收液相对密度达到1.30～1.32时送入中和器，再加入碳酸氢铵中和反应至终点，经离心分离、干燥，可制得亚硫酸铵成品。

化学性质

单水合亚硫酸铵为白色或淡黄色溶液，在受热条件下分解。饱和溶液的相对密度在20℃时为1.1995，呈碱性，并对钢铁有较强的腐蚀性。

用途

主要用于造纸工业；其次用于生产快速显影液硫代硫酸铵的原料；还用作有机合成中的还原剂和磺化剂；同时也是日用化学品卷发液的重要原料之一。

反应信息

• 作为反应物：
  描述：

  2-溴-7-羟基萘 、 氨 、 单水合亚硫酸铵 、 盐酸 在 乙酸乙酯 、 sodium hydroxide 、 ice 、 Brine 、 7-溴-2-萘胺 作用下， 以 乙酸乙酯 为溶剂， 反应 27.0h， 以to obtain the title compound (Intermediate 26, 1.00 g)的产率得到7-溴-2-萘胺
  参考文献：
  名称：

  Substituted phenylalkanoic acid derivatives and use thereof

  摘要：

  化合物的化学式为（I）或其盐：1其中n表示1至3的整数，R表示具有3至8个碳原子的烷基基团，以及由以下式表示的基团：R1(CH2)k-（其中k表示0或1至3的整数；R1表示具有3至7个碳原子的饱和环烷基团或具有6至8个碳原子的饱和缩合环烷基团，基团R1可以被具有1至4个碳原子的低级烷基团取代）等，Ar表示类似萘-1-基团的缩合双环基团，具有抑制前列腺素和白三烯产生的作用，对于预防和/或治疗由这些脂质介质引起的各种炎症性疾病等非常有用。

  公开号：

  US20040044258A1

文献信息

• Substituted phenylalkanoic acid derivatives and use thereof
  申请人：——

  公开号：US20040044258A1

  公开（公告）日：2004-03-04

  A compound represented by the formula (I) or a salt thereof: 1 wherein n represents an integer of 1 to 3, R represents an alkyl group having 3 to 8 carbon atoms, a group represented by the following formula: R 1 (CH 2 ) k — (wherein k represents 0 or an integer of 1 to 3; R 1 represents a saturated cyclic alkyl group having 3 to 7 carbon atoms or a saturated condensed cyclic alkyl group having 6 to 8 carbon atoms, and the group R 1 may be substituted with a lower alkyl group having 1 to 4 carbon atoms) and the like, and Ar represents a condensed bicyclic group such as naphthalen-1-yl group, which has suppressing action on prostaglandin and leukotriene production and is useful for prophylactic and/or therapeutic treatment of various inflammatory diseases and the like caused by these lipid mediators.

  化合物的化学式为（I）或其盐：1其中n表示1至3的整数，R表示具有3至8个碳原子的烷基基团，以及由以下式表示的基团：R1(CH2)k-（其中k表示0或1至3的整数；R1表示具有3至7个碳原子的饱和环烷基团或具有6至8个碳原子的饱和缩合环烷基团，基团R1可以被具有1至4个碳原子的低级烷基团取代）等，Ar表示类似萘-1-基团的缩合双环基团，具有抑制前列腺素和白三烯产生的作用，对于预防和/或治疗由这些脂质介质引起的各种炎症性疾病等非常有用。

表征谱图