(4-benzoyloxy-2,2,6,6-tetramethylpiperidin-1-yloxy)methane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4-benzoyloxy-2,2,6,6-tetramethylpiperidin-1-yloxy)methane
• 英文别名: 1-methoxy-4-benzoyloxy-2,2,6,6-tetramethylpiperidine；4-benzoyloxy-1-methoxy-2,2,6,6-tetramethylpiperidine；1-methoxy-2,2,6,6-tetramethylpiperidin-4-yl benzoate；(1-methoxy-2,2,6,6-tetramethylpiperidin-4-yl) benzoate
• 化学式: C₁₇H₂₅NO₃
• 分子量: 291.39
• InChiKey: XUEKSPYRNPPYNH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  38.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  4-(benzyloxycarbonyl)-2,2,6,6-tetramethylpiperidine-1-oxyl 在 (pyridine)Co(dimethylglyoxime)2CH3 作用下， 反应 1.5h， 以49%的产率得到(4-benzoyloxy-2,2,6,6-tetramethylpiperidin-1-yloxy)methane
  参考文献：
  名称：

  Tada, Masaru; Yoshihara, Takao; Sugano, Kiyohiko, Journal of the Chemical Society. Perkin transactions I, 1995, # 15, p. 1941 - 1944

  摘要：

  DOI：

文献信息

• Eclipsed ground-state conformations of the tert-butyl-X bond in N-tert-butoxy- and N-neopentyl-2,2,6,6-tetramethylpiperidine. X-ray crystal structure determinations and molecular mechanics calculations
  作者：J. Edgar Anderson、Derek A. Tocher、John E. T. Corrie、Lodovico Lunazzi

  DOI：10.1021/ja00062a012

  日期：1993.5

  X-ray crystallographic studies of derivatives of N-methoxy- and N-tert-butoxy-2,2,6,6-tetramethylpiperidine show that as expected the N-O bond is staggered with respect to the C-H bonds of the methoxy group in the former case, yet it eclipses a C-methyl bond of the tert-butyl group in the latter case. Molecular mechanics calculations confirm this and show that likewise the preferred conformation of

  N-甲氧基-和 N-叔丁氧基-2,2,6,6-四甲基哌啶衍生物的 X 射线晶体学研究表明，正如预期的那样，NO 键相对于前者中甲氧基的 CH 键是交错的在后一种情况下，它使叔丁基的 C-甲基键黯然失色。分子力学计算证实了这一点，并表明同样优选的 N-新戊基-2,2,6,6-四甲基哌啶构象的 CH 2 与叔丁基键重叠，而在相应的 N-乙基化合物中，CH 2 与甲基键是交错的。报告了所有这些分子的四甲基环己基类似物和轴向构象的计算
• Non-migrating 1-hydrocarbyloxy hindered amine derivatives as polymer
  申请人：Ciba-Geigy Corporation

  公开号：US05145893A1

  公开（公告）日：1992-09-08

  1-Hydrocarbyloxy substituted hindered amine compounds which also contain a reactive functional group such as hydroxy, amino, oxirane or carboxyl can be chemically attached to selected polymer substrates by condensation reactions to give polymers containing a chemically-bonded, non-migrating stabilizer having excellent stabilization efficacy for protecting said polymer substrate from the adverse effects of actinic light.

  含有反应性官能团（例如羟基、氨基、环氧或羧基）的1-烷氧基取代的受阻胺化合物可以通过缩合反应与选定的聚合物基质化学结合，从而得到含有化学键合的、不迁移的稳定剂的聚合物，其具有优异的稳定效果，可以保护该聚合物基质免受光化学反应的不利影响。
• N-hydrocarbyloxy hindered amine light stabilizers with phosphorus
  申请人：Ciba-Geigy Corporation

  公开号：US05021481A1

  公开（公告）日：1991-06-04

  N-Hydrocarbyloxy derivatives of phosphorus substituted 4-amino- and 4-hydroxy-2,2,6,6-tetramethylpiperidine are effective light stabilizers for polymer compositions. These phosphorus compounds include phosphites and cyclic phosphites such as 1,3,2-dioxaphospholanes, 1,3,2-dioxaphosphorinanes, 1,3,2-oxazaphospholidines, 1,3,2-diazaphospholidines, 1,3,2-dioxaphosphocins, 1,3,2-dioxaphosphepins and 2,4,8,10-tertraoxa-3,9-diphosphaspiro[5,5]-undecanes.

  磷取代的4-氨基和4-羟基-2,2,6,6-四甲基哌啶的N-烷氧基衍生物是聚合物组成中有效的光稳定剂。这些磷化合物包括亚磷酸酯和环磷酸酯，如1,3,2-二氧杂环磷酮，1,3,2-二氧杂磷杂环丙烷，1,3,2-噁唑磷杂环戊烷，1,3,2-二氮杂磷杂环戊烷，1,3,2-二氧杂磷杂环辛烷，1,3,2-二氧杂磷杂环戊烯和2,4,8,10-四氧杂-3,9-二磷杂螺[5,5]-十一烷。
• Polysubstituted n-hydrocarbyloxy hindered amine light stabilizers
  申请人：Ciba-Geigy Corporation

  公开号：US05021577A1

  公开（公告）日：1991-06-04

  Polysubstituted N-hydrocarbyloxy hindered amines are effective light stabilizers in protecting organic substrates against the deleterious effects of actinic light.

  多取代的N-羟基烷氧基受阻胺是有效的光稳定剂，可保护有机基质免受光化学光的有害影响。
• Process for preparing N-methoxy derivatives of
  申请人：Ciba-Geigy Corporation

  公开号：US05374729A1

  公开（公告）日：1994-12-20

  N-Methoxy derivatives of the sterically hindered amines 4-hydroxy-2,2,6,6-tetramethylpiperidine and 2,2,6,6-tetramethyl-4-piperidone are prepared from the corresponding N-oxyl hindered amine by combining hydrogen peroxide and a peroxide-decomposing transition metal salt in the presence of dimethyl sulfoxide.

  本文介绍了通过将过氧化氢和过氧化分解过渡金属盐与二甲基亚砜共同存在，从相应的N-氧代受阻胺制备出受体位阻胺4-羟基-2,2,6,6-四甲基哌啶和2,2,6,6-四甲基-4-哌啶酮的N-甲氧基衍生物的方法。