2-(2-(3,4-Dimethoxybenzylidene)hydrazineyl)pyridine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(2-(3,4-Dimethoxybenzylidene)hydrazineyl)pyridine
• 英文别名: N-[(E)-(3,4-dimethoxyphenyl)methylideneamino]pyridin-2-amine
• 化学式: C₁₄H₁₅N₃O₂
• 分子量: 257.29
• InChiKey: WEVXWRHMOLCJHK-MHWRWJLKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  55.7
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• COMPOUNDS FOR MODULATING T-CELLS
  申请人：Trede Nikolaus S.

  公开号：US20080293739A1

  公开（公告）日：2008-11-27

  Disclosed are compounds and compositions that modulate T-cells. Such compounds can be used to treat T-cell mediated disease like T-ALL, rheumatoid arthritis, multiple sclerosis, and graft-vs-host disease (GvHD), to name but a few. The compounds have a general structure as shown in Formula I. Ar 1 -L-Ar 2 I wherein Ar 1 and Ar 2 , are independent of one another, a substituted aryl, unsubstituted aryl, substituted heteroaryl, or unsubstituted heteroaryl; and L is a bond or a linker spanning two, three, four, or five atoms.
• US8039505B2
  申请人：——

  公开号：US8039505B2

  公开（公告）日：2011-10-18