4-(morpholin-4-yl)-6-{(2E)-2-[(6-nitro-1,3-benzodioxol-5-yl)methylidene]hydrazinyl}-N-phenyl-1,3,5-triazin-2-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并间二氧杂环戊烯类
• 英文名称: 4-(morpholin-4-yl)-6-{(2E)-2-[(6-nitro-1,3-benzodioxol-5-yl)methylidene]hydrazinyl}-N-phenyl-1,3,5-triazin-2-amine
• 英文别名: 6-morpholin-4-yl-2-N-[(E)-(6-nitro-1,3-benzodioxol-5-yl)methylideneamino]-4-N-phenyl-1,3,5-triazine-2,4-diamine
• 化学式: C21H20N8O5
• 分子量: 464.4
• InChiKey: LVVDRXIPMDROJG-WSDLNYQXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  34
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  152
• 氢给体数：
  2
• 氢受体数：
  12

文献信息

• COMPOSITIONS AND METHODS FOR APOPTOSIS MODULATORS
  申请人：Wu Jay Jie-Qiang

  公开号：US20100267671A1

  公开（公告）日：2010-10-21

  The present invention includes and relates generally to compounds which modulate apoptosis in cells. The present invention also provides pharmaceutical compositions containing these compounds, methods of making these compounds, and methods of using these compounds and pharmaceutical compositions for treatment of diseases associated with irregular apoptosis in cells.
• [EN] COMPOSITIONS AND METHODS FOR APOPTOSIS MODULATORS<br/>[FR] COMPOSITIONS ET PROCÉDÉS POUR MODULATEURS D'APOPTOSE
  申请人：VM DISCOVERY INC

  公开号：WO2009023558A1

  公开（公告）日：2009-02-19

  The present invention includes relates generally to compounds which modulate apoptosis in cells. The present invention also provides pharmaceutical compositions containing these compounds, methods of making these compounds, and methods of using these compounds and pharmaceutical compositions for treatment of diseases associated with irregular apoptosis in cells.