(6R,7R)-3-[(1,4-diaminopyrimidin-1-ium-2-yl)sulfanylmethyl]-7-[[2-(2,5-dichlorophenyl)sulfanylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酰胺类
• 英文名称: (6R,7R)-3-[(1,4-diaminopyrimidin-1-ium-2-yl)sulfanylmethyl]-7-[[2-(2,5-dichlorophenyl)sulfanylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 化学式: C20H19Cl2N6O4S3+
• 分子量: 574.5
• InChiKey: DQSFNQFCMVPOAM-CRAIPNDOSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  35
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  231
• 氢给体数：
  4
• 氢受体数：
  10

文献信息

• Novel cephalosporin compounds and process for preparing the same
  申请人：——

  公开号：US20030162762A1

  公开（公告）日：2003-08-28

  The present invention relates to a novel cephalosporin compound, and pharmaceutically acceptable non-toxic salt, physiologically hydrolysable ester, hydrate, solvate or isomer thereof, to a pharmaceutical composition containing the compound and to a process for preparing the compound.

  本发明涉及一种新型头孢菌素化合物，以及其药学上可接受的无毒盐、生理可水解酯、水合物、溶剂合物或同分异构体，还涉及含有该化合物的药物组合物以及制备该化合物的方法。
• NOVEL CEPHALOSPORIN COMPOUNDS AND PROCESS FOR PREPARING THE SAME
  申请人：LG Life Sciences Ltd.

  公开号：EP1299397A1

  公开（公告）日：2003-04-09
• [EN] NOVEL CEPHALOSPORIN COMPOUNDS AND PROCESS FOR PREPARING THE SAME<br/>[FR] NOUVEAUX COMPOSES DE CEPHALOSPORINE ET PROCEDE DE PREPARATION
  申请人：LG CHEM INVESTMENT LTD

  公开号：WO2002004464A1

  公开（公告）日：2002-01-17

  The present invention relates to a novel cephalosporin compound, and pharmaceutically acceptable non-toxic salt, physiologically hydrolysable ester, hydrate, solvate or isomer thereof, to a pharmaceutical composition containing the compound and to a process for preparing the compound.