Catechol 2-hydroxypropionate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: Catechol 2-hydroxypropionate
• 英文别名: (2-hydroxyphenyl) 2-hydroxypropanoate
• 化学式: C₉H₁₀O₄
• 分子量: 182.17
• InChiKey: ABVWGODLBSWPHE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Stretched film structure of the poly-1,3-phenylene terephthalate type
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0052927A2

  公开（公告）日：1982-06-02

  A monoaxially or biaxially stretched film structure, or a heat-set structure thereof, of an unstretched film of an aromatic polyester having an intrinsic viscosity, determined in p-chlorophenol at 50°C, of 0.4 to 2.0 and composed of [A] polybasic carboxylic acid component units consisting of terephthalic acid units (a1) and units (a2) of a polybasic carboxylic acid otherthan terephthalic acid, the proportion of the units (a2) being up to 25 mole% based on the units (a,) and units (a2) combined, and [B] polyol component units consisting of resorcinol units (b1) and units (b2) of a polyol other than resorcinol, the proportion of the units (b2) being up to 25 mole% based on the units (b1) and (b2) combined.

  一种单轴或双轴拉伸薄膜结构，或其热固结构，由芳香族聚酯的未拉伸薄膜组成，其固有粘度（在对氯苯酚中于 50℃测定）为 0.4 至 2.A] 由对苯二甲酸单元（a1）和对苯二甲酸以外的多基性羧酸单元（a2）组成的多基性羧酸组分单元，单元（a2）的比例为单元（a. ）和单元（a2）总和的 25 摩尔%、)和单元(a2)的总和，单元(a2)的比例不超过 25 摩尔%，以及 [B] 由间苯二酚单元(b1)和间苯二酚以外的多元醇单元(b2)组成的多元醇组分单 元，单元(b2)的比例不超过 25 摩尔%，单元(b1)和单元(b2)的总和。
• Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use
  申请人：Yu, Ruey J., Dr.

  公开号：EP0413528A1

  公开（公告）日：1991-02-20

  Preventive as well as therapeutic treatment to alleviate cosmetic conditions and symptoms of dermatologic disorders with amphoteric compositions containing alpha hydroxyacids, alpha ketoacids, related compounds or polymeric forms of hydroxyacids is disclosed. The cosmetic conditions and the dermatologic disorders in which the amphoteric compositions and the polymeric compounds may be useful include dry skin, dandruff, acne, keratoses, psoriasis, eczema, pruritus, age spots, lentigines, melasmas, wrinkles, warts, blemished skin, hyperpigmented skin, kyperkeratotic skin, inflammatory dermatoses, skin changes associated with aging, and skin requiring cleansers.

  本发明公开了含有α-羟基酸、α-酮酸、相关化合物或羟基酸聚合形式的两性组合物的预防和治疗方法，以缓解美容状况和皮肤病症状。两性组合物和聚合化合物可用于治疗的美容病症和皮肤病包括皮肤干燥、头皮屑、痤疮、角化病、牛皮癣、湿疹、瘙痒症、老年斑、色斑、黑斑、皱纹、疣、瑕疵皮肤、色素沉着皮肤、角化过度皮肤、炎症性皮肤病、与衰老有关的皮肤变化以及需要清洁剂的皮肤。
• Cosmetic composition containing acetylated oligoglucuronans
  申请人：Sederma, S.A.S.

  公开号：US10159636B2

  公开（公告）日：2018-12-25

  The present invention relates to the field of cosmetic and dermopharmaceutical compositions. It concerns oligomer compounds of D-glucuronic acid or D-glucuronate with a β (1-4) sequence (or oligoglucuronans) containing a degree of acetylation specifically between 8.7±0.5 and 9.2±0.5% by weight of O—CO—CH3 group compared to the weight of glucuronic acid and with a degree of polymerisation (DP) of 18-19±2. The oligomer compounds according to the present invention are intended to stimulate the elasticity of the dermis and epidermis although they also act to increase dermo-epidermal cohesion in order to combat skin ageing, lines, wrinkles, visible and/or tactile skin discontinuities, loss of firmness, elasticity and tone and to combat skin tissue deformability. The invention also concerns a cosmetic composition containing at least one compound as recited according to the present invention.

  本发明涉及化妆品和皮肤药物组合物领域。本发明涉及具有 β (1-4) 序列的 D-葡萄糖醛酸或 D-葡萄糖醛酸的低聚物化合物（或低聚葡萄糖醛酸），其乙酰化程度与葡萄糖醛酸的重量相比，O-CO-CH3 基团的重量占 8.7±0.5 至 9.2±0.5%，聚合度（DP）为 18-19±2。根据本发明的低聚物化合物旨在刺激真皮层和表皮层的弹性，但它们也能增加真皮层和表皮层的凝聚力，以对抗皮肤老化、细纹、皱纹、可见和/或触觉皮肤不连续性、紧致度、弹性和肤色的丧失，并对抗皮肤组织的变形性。本发明还涉及一种含有至少一种根据本发明所述化合物的化妆品组合物。
• Light-absorbing compositions and methods of use
  申请人：Allele Biotechnology & Pharmaceuticals, Inc.

  公开号：US10842728B2

  公开（公告）日：2020-11-24

  The present disclosure relates to methods and compositions comprising naturally occurring light absorbing molecules for preventing damages from light exposure. Specific embodiments of this disclosure include fluorescent proteins from Brachiostoma lanceolatum.

  本公开涉及包含天然光吸收分子的方法和组合物，用于防止光照射造成的损害。本公开的具体实施方案包括来自 Brachiostoma lanceolatum 的荧光蛋白。
• Treatment of dandruff
  申请人：Unilever Home & Personal Care USA, Division of Conopco, Inc.

  公开号：US20020168327A1

  公开（公告）日：2002-11-14

  Dandruff and symptoms of dandruff can be treated using lipophilic agents or lipid precursor and/or promoters to strengthen the scalp. The lipophilic agents or lipid precursor and/or promoters are preferably used in conjunction with an antifungal agent which has activity against Malassezia spp, particularly Malassezia furfur . Suitable antifungal agents include those conventionally used for the treatment of dandruff including, for example, zinc pyrithrone (ZnPTO), octopirox and azole antifungal agents such as climbazole and ketocanazole. The antifungal agents may be used singularly or as a mixture of one or more antifungal agents.

  头皮屑和头皮屑症状可使用亲脂剂或脂质前体和/或促进剂来治疗，以增强头皮的功效。亲脂剂或脂质前体和/或促进剂最好与具有抗马拉色菌活性的抗真菌剂一起使用，特别是 糠秕马拉色菌 .合适的抗真菌剂包括传统上用于治疗头皮屑的抗真菌剂，例如吡蚜酮锌 (ZnPTO)、辛吡罗和唑类抗真菌剂，如爬山唑和酮康唑。这些抗真菌剂可单独使用，也可作为一种或多种抗真菌剂的混合物使用。