{3-[4-(3-cyclohexyl-1-phenethylureido)phenylsulphanyl]phenyl}acetic acid | 735273-77-5

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: {3-[4-(3-cyclohexyl-1-phenethylureido)phenylsulphanyl]phenyl}acetic acid
• 英文别名: {3-[4-(3-cyclohexyl-1-phenethylureido)phenyl-sulfanyl]phenyl}acetic acid；2-[3-[4-[Cyclohexylcarbamoyl(2-phenylethyl)amino]phenyl]sulfanylphenyl]acetic acid
• CAS: 735273-77-5
• 化学式: C₂₉H₃₂N₂O₃S
• 分子量: 488.651
• InChiKey: UGPZLKRITAGTCQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  35
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  94.9
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] COMPOUNDS WHICH ARE MODULATORS OF THE PPAR-TYPE RECEPTORS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS<br/>[FR] COMPOSES FONCTIONNANT COMME MODULATEURS DE RECEPTEURS DE TYPE PPAR ET LEUR UTILISATION DANS DES COMPOSITIONS COSMETIQUES OU PHARMACEUTIQUES
  申请人：GALDERMA RES & DEV

  公开号：WO2004072022A1

  公开（公告）日：2004-08-26

  The invention relates to novel compounds which correspond to the following general formula (I): their method of preparation, and their use in pharmaceutical compositions intended for use in human or veterinary medicine (in dermatology and in the field of cardiovascular diseases, immune diseases and/or diseases linked to lipid metabolism), or in cosmetic compositions.

  该发明涉及与以下一般式（I）相对应的新化合物，它们的制备方法，以及它们在用于人类或兽医药物组合物中的用途（在皮肤病学和心血管疾病、免疫疾病和/或与脂质代谢相关的疾病领域），或者在化妆品组合物中的用途。
• Novel modulators of the PPAR-type receptors and cosmetic/pharmaceutical compositions comprised thereof
  申请人：Diaz Philippe

  公开号：US20060035969A1

  公开（公告）日：2006-02-16

  Novel compounds which modulate PPAR-type receptors have the following general formula (I): and are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology and in the fields of cardiovascular diseases, immune diseases and/or diseases linked to lipid metabolism), or are formulated into cosmetic compositions.

  调节 PPAR 型受体的新型化合物具有以下通式 (I)： 并配制成适用于人类或兽医用药（皮肤病和心血管疾病、免疫疾病和/或与脂质代谢有关的疾病）的药物组合物，或配制成化妆品组合物。
• COMPOUNDS WHICH ARE MODULATORS OF THE PPAR-TYPE RECEPTORS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS
  申请人：Galderma Research & Development, S.N.C.

  公开号：EP1594837A1

  公开（公告）日：2005-11-16
• Cosmetic/dermatological applications of PPAR receptor activators
  申请人：Jomard Andre

  公开号：US20070065471A1

  公开（公告）日：2007-03-22

  Cosmetic/pharmaceutical compositions useful for regulating the size of sebaceous glands and, in particular, for inhibiting sebum production, or for treating pathologies entailing an overproduction of sebum, or for treating greasy skin and/or a scalp prone to dandruff, contain thus effective amounts of at least one activator of PPAR type receptors.