(2,3,5,6-tetrafluoro-4-methylphenyl)methyl 3-[(E)-2-chloro-3,3,3-trifluoroprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2,3,5,6-tetrafluoro-4-methylphenyl)methyl 3-[(E)-2-chloro-3,3,3-trifluoroprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate
• 化学式: C₁₇H₁₄ClF₇O₂
• 分子量: 418.7
• InChiKey: ZFHGXWPMULPQSE-RUDMXATFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  9

文献信息

• Preparation of 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol
  申请人：——

  公开号：US20040063993A1

  公开（公告）日：2004-04-01

  A process for the preparation of 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol comprising hydrogenating 4-methyl-2,3,5,6-tetrafluorobenzonitrile to 4-methyl-2,3,5,6-tetrafluorobenzylamine and converting 4-methyl-2,3,5,6-tetrafluorobenzylamine to 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol. The process optionally also comprises the further step of reacting 4-Methyl-2,3,5,6-tetrafluobenzyl alcohol with cis-Z-3-(2-chloro-1,1,1-trifluoro-2-propenyl)-2,2-dimethylcyclopropanecarbonyl chloride to the form tefluthrin. 4-Methyl-2,3,5,6-tetrafluorobenzylamine and salts thereof are also claimed.

  一种制备4-甲基-2,3,5,6-四氟苯甲醇的方法，包括将4-甲基-2,3,5,6-四氟苯甲腈加氢制得4-甲基-2,3,5,6-四氟苯甲胺，然后将4-甲基-2,3,5,6-四氟苯甲胺转化为4-甲基-2,3,5,6-四氟苯甲醇。该方法还可以包括将4-甲基-2,3,5,6-四氟苯甲醇与顺式-Z-3-(2-氯-1,1,1-三氟-2-丙烯基)-2,2-二甲基环丙烷羧酰氯反应以形成特氟氰。同时还声明了4-甲基-2,3,5,6-四氟苯甲胺及其盐。
• Preparation of 4-methyl-2, 3, 5, 6-tetrafluorobenzyl alcohol
  申请人：Jones Heavon Raymond Vincent

  公开号：US20050054886A1

  公开（公告）日：2005-03-10

  A process for the preparation of 1,4-bis(hydroxymethyl)-2,3,5,6-tetrafluorobenzene comprising fluorinating 2,3,5,6-tetrachloroterephthalonitrile to obtain 2,3,5,6-tetrafluoroterephthalonitrile, hydrogenating 2,3,5,6-tetrafluoroterephthalonitrile to give 1,4-bis(aminomethyl)-2,3,5,6-tetrafluorobenzene and converting 1,4-bis(aminomethyl)-2,3,5,6-tetrafluorobenzene to 1,4-bis(hydroxymethyl)-2,3,5,6-tetrafluorobenzene.

  制备1,4-双(羟甲基)-2,3,5,6-四氟苯的过程包括氟化2,3,5,6-四氯对苯二腈以获得2,3,5,6-四氟对苯二腈，将2,3,5,6-四氟对苯二腈氢化以得到1,4-双(氨甲基)-2,3,5,6-四氟苯，并将1,4-双(氨甲基)-2,3,5,6-四氟苯转化为1,4-双(羟甲基)-2,3,5,6-四氟苯。
• PYRETHROID FORMULATIONS OF REDUCED PARESTHESIA
  申请人：ICI AMERICAS INC.

  公开号：EP0538246A1

  公开（公告）日：1993-04-28
• PREPARATION OF 4-METHYL-2,3,5,6-TETRAFLUOROBENZYL ALCOHOL
  申请人：Syngenta Limited

  公开号：EP1332125B1

  公开（公告）日：2004-09-29
• BIOLOGICAL EFFICACY OF AGROCHEMICAL COMPOSITIONS ON APPLICATION IN THE GROWTH SUBSTRATE SUITABLE FORMULATIONS AND USE THEREOF
  申请人：Marczok Peter

  公开号：US20090306147A1

  公开（公告）日：2009-12-10

  In soil applications, the action of crop protection compositions comprising active compounds from the classes of the neonicotinoids, the pyrethroids, the butenolides, the ketoenols, the phenylpyrazoles or the fungicides can be improved by adjuvants. The present invention describes corresponding methods and suitable compositions.