(2S,6R)-2,6-dimethyl-1,4-bis[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]piperazine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: (2S,6R)-2,6-dimethyl-1,4-bis[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]piperazine
• 化学式: C₃₆H₄₄N₄O₆
• 分子量: 628.8
• InChiKey: MOLAYHOYEBVKFM-PSWAGMNNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  46
• 可旋转键数：
  12
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  87.6
• 氢给体数：
  0
• 氢受体数：
  10

文献信息

• AGENT FOR PREVENTION/THERAPY OF DISEASE CAUSED BY KERATINOCYTE GROWTH
  申请人：Edano Toshiyuki

  公开号：US20090042901A1

  公开（公告）日：2009-02-12

  The present invention relates to an agent for the prevention/therapy of a disease caused by keratinocyte growth, which comprises, as an active ingredient, a compound represented by General Formula (1): wherein A represents a group selected from groups of the following formulas: X represents CH or N; Y represents CH 2 or C═O; Z represents CH or N; R 1 represents an alkoxy group; R 2 and R 3 each independently represent an alkyl group; R 4 represents an alkyl group, and a group of the following formula: R 5 each independently represent an alkoxy group or an alkylthio group; m represents an integer from 1 to 3; n represents an integer of 1 or 2; and o represents an integer of 1 or 2, or a salt thereof, or a solvate of the compound or the salt.