6-chloro-1-iodonaphthalene

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 6-chloro-1-iodonaphthalene
• 英文别名: 6-Chlor-1-jod-naphthalin；6-Chloro-1-iodonaphthalene
• 化学式: C₁₀H₆ClI
• 分子量: 288.515
• InChiKey: FHSSEUFOTRLKFH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  6-chloro-1-iodonaphthalene 在 tris-(dibenzylideneacetone)dipalladium(0) 、 N-氯代丁二酰亚胺 、 水 、 溶剂黄146 、 N,N-二异丙基乙胺 、 4,5-双二苯基膦-9,9-二甲基氧杂蒽 作用下， 以 1,4-二氧六环 为溶剂， 反应 4.0h， 生成 6-氯萘-1-磺酰氯
  参考文献：
  名称：

  [EN] NOVEL NAPHTHYL AND ISOQUINOLINE SULFONAMIDE DERIVATIVES
  [FR] NOUVEAUX DÉRIVÉS DE NAPHTYLE ET ISOQUINOLINE SULFONAMIDE

  摘要：

  The invention relates to novel compounds having the general formula (I) wherein R1, R2, X1, X2, X3and W are as described herein, composition including the compounds and methods of using the compounds.

  公开号：

  WO2024017858A1
• 作为产物：
  描述：

  6-氯-1-萘胺 在 对甲苯磺酸 、 potassium iodide 、 sodium nitrite 作用下， 以 乙腈 、 水 为溶剂， 以5 %的产率得到6-chloro-1-iodonaphthalene
  参考文献：
  名称：

  [EN] NOVEL NAPHTHYL AND ISOQUINOLINE SULFONAMIDE DERIVATIVES
  [FR] NOUVEAUX DÉRIVÉS DE NAPHTYLE ET ISOQUINOLINE SULFONAMIDE

  摘要：

  The invention relates to novel compounds having the general formula (I) wherein R1, R2, X1, X2, X3and W are as described herein, composition including the compounds and methods of using the compounds.

  公开号：

  WO2024017858A1

文献信息

• NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME
  申请人：LG Chem, Ltd.

  公开号：EP4063367A1

  公开（公告）日：2022-09-28

  The present disclosure provides a novel compound and an organic light emitting device including the same.

  本公开提供了一种新型化合物和包括其在内的有机发光器件。
• Synthesis, Reactivity, and Catalytic Applications of Isolable (NHC)Cu(CHF₂) Complexes
  作者：James R. Bour、Stavros K. Kariofillis、Melanie S. Sanford

  DOI：10.1021/acs.organomet.7b00025

  日期：2017.4.10

  Difluoromethyl copper complexes have been proposed as key intermediates in a variety of Cu-catalyzed difluoromethylation reactions. However, studies of these putative intermediates have been impeded by the low stability of these [Cu(CHF2)] species. This report describes the synthesis of isolable N-heterocyclic carbene ligated copper(I) difluoromethyl complexes. The stoichiometric reactions of these complexes with aryl electrophiles (i.e., diaryliodonium salts, aryl iodides, and aryl bromides) are described. In addition, N-heterocyclic carbene copper(I) species are demonstrated to serve as catalysts for the cross-coupling of aryl iodides with (difluoromethyl)trimethylsilane to afford difluoromethyl arene products.
• [EN] NOVEL NAPHTHYL AND ISOQUINOLINE SULFONAMIDE DERIVATIVES<br/>[FR] NOUVEAUX DÉRIVÉS DE NAPHTYLE ET ISOQUINOLINE SULFONAMIDE
  申请人：[en]F. HOFFMANN-LA ROCHE AG

  公开号：WO2024017858A1

  公开（公告）日：2024-01-25

  The invention relates to novel compounds having the general formula (I) wherein R1, R2, X1, X2, X3and W are as described herein, composition including the compounds and methods of using the compounds.