(5R)-5-(aminomethyl)-3-[3-fluoro-4-(2-oxo-1,3-oxazolidin-3-yl)phenyl]-1,3-oxazolidin-2-one

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (5R)-5-(aminomethyl)-3-[3-fluoro-4-(2-oxo-1,3-oxazolidin-3-yl)phenyl]-1,3-oxazolidin-2-one
• 化学式: C₁₃H₁₄FN₃O₄
• 分子量: 295.27
• InChiKey: AYFFVFFQRBTRNJ-SECBINFHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  85.1
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• Novel heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them
  申请人：DR. REDDY'S RESEARCH FOUNDATION

  公开号：US20030065175A1

  公开（公告）日：2003-04-03

  The present invention relates to novel oxazolidinone compounds of the general formula (I) 1 where R 1 , R 2 , R 3 , Y 1 , Y 2 , Y 3 , and Z are as defined in the description; their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutical acceptable salts, their pharmaceutically acceptable solvates and pharmaceutical compositions containing them.

  本发明涉及一种新型噁唑啉化合物，其通式为（I）1，其中R1、R2、R3、Y1、Y2、Y3和Z如描述中所定义；它们的衍生物、类似物、互变异构体、立体异构体、多晶形态、药学上可接受的盐、药学上可接受的溶剂化合物以及含有它们的制药组合物。
• HETEROCYCLIC COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
  申请人：Dr. Reddy's Laboratories Ltd.

  公开号：EP1345913A2

  公开（公告）日：2003-09-24
• US7030148B2
  申请人：——

  公开号：US7030148B2

  公开（公告）日：2006-04-18
• US7183301B2
  申请人：——

  公开号：US7183301B2

  公开（公告）日：2007-02-27
• [EN] HETEROCYCLIC COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM<br/>[FR] COMPOSÉS HÉTÉROCYCLIQUES ANTIBACTÉRIENS, MODE D'ÉLABORATION ET COMPOSITIONS PHARMACEUTIQUES AINSI OBTENUES
  申请人：——

  公开号：WO2002051819A9

  公开（公告）日：2003-08-07

  [EN] The present invention relates to novel oxazolidinone compounds of the general formula (I) where R<1>, R<2>, R<3>, Y<1>, Y<1>, Y<2>, Y<3>, and Z are as defined in the description; their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutical compositions containing them.
  [FR] La présente invention concerne des composés oxazolidinone représentés par la formule générale (I) dans laquelle les R<1>, R<2>, R<3>, Y<1>, Y<1>, Y<2>, Y<3>, et Z sont conformes à la définition qui en est donnée dans la description. L'invention concerne également leurs dérivés, analogues, tautomères, stéréoisomères, polymorphes, sels et solvates pharmaceutiquement admis, et des compositions pharmaceutiques les contenant.